N-acetyl-β-D-glucosaminidase,alanine aminopeptidase and protein: Creatinine ratio as early indicators of diabetic microangiopathy

The urinary excretion patterns of N-acetyl-β-D-glucosaminidase (NAG), alanine aminopeptidase (AAP) and protein/creatinine ratio (UP/UCR) were studied in 133 diabetic subjects under treatment, 7 patients with established diabetic nephropathy (DN) and 79 carefully selected (age-matched) healthy subjects. NAG, AAP and UP/UCR were highly elevated in DN, while in diabetics urinary NAG levels correlated well with the degree of long-term metabolic control indicated by glycosylated hemoglobin (GHB or Hba1). Both AAP and UP/UCR were found to be more sensitive than NAG, but less specific. Urinary NAG and AAP assays thus offer simple, sensitive and non-invasive techniques for prognostic indication of the onset of microangiopathic changes in long-term diabetic subjects.     

基于SSM分折的科研评价系统探讨

科技评价体系是一个复杂的,多目标评价体系。当今科技评价已逐渐从强调科研产出,转向同时关注资源的使用效率,注重科技创新能力的提升和对国民经济发展的贡献。如何建立一个客观、公正、健全、规范的,且具备可操作性的科学评价体系引起了政府和科技界的广泛关注。本文以SSM系统分析为基础,从3E出发探讨了评价指标体系的构建和评价系统的设计。基于系统分析基础上形成的指标体系,既考虑了直接的产出,又分析了内部运行机制,形成的指标体系相对更全面、完整,在此基础上针对具体评价内容选择适宜的评价方法,可定量或定性,软硬结合,具有透明性和延展性,同时易与决策管理部门交流。     

Editorial

Knowledge Management Research & Practice -     

Editorial

Knowledge Management Research & Practice -     

Left-handed materials in magnetized metallic magnetic thin films

INTRODUCTION Veselago (1968) showed that if both the permit- tivity ε and the magnetic permeability μ of a material are negative, the propagation direction of an elec- tromagnetic (EM) wave will be opposite to its energy flow direction. Such media are called left-handed materials (LHMs) since the electric field E, magnetic field H, and wave vector k in these media form a left-hand triplet of vectors, instead of a right-hand triplet observed in conventional materials. For a long time, …     

The assessment and prevention of answer copying on undergraduate multiple-choice examinations

Multiple-choice examination answer copying was indexed by a comparison of the numbers of items answered incorrectly, and in the same way, as adjacent and distant classmates. In Experiment I, which involved a regular university examination, significant copying did occur, did not differ from front to rear of the lecture hall, and appeared primarily among individuals seated next to one another. Copying was not related to the order in which the examinations were returned. Number correct was related to turn-in order in a U-shaped fashion. No significant copying appeared in a second experiment, where test performance did not contribute to course grade.     

University Choice: What Influences the Decisions of Academically Successful Post‐16 Students?

The questionnaire survey reported in this paper is part of an ongoing evaluation of the effect of a bursary scheme on recruitment to Cambridge University. It sought to identify factors that encouraged or discouraged highly successful A Level students from applying to Cambridge. Findings reveal three main dimensions associated with the decision to apply to Cambridge, the nature of the courses, the prestige of the university and anxiety about the application process combined with fear of failure. Further analyses showed that there were complex interactions between these three dimensions which governed the decision to apply to Cambridge. These findings are relevant to other prestigious universities. The availability of a bursary did appear to influence the decisions of those who were eligible, but its influence was not as great as some of the other factors.