彰显独特十法则

你认为自己是独一无二的吗？世上每一个人都是独特的,都拥有区别于别人的特点。让我们把自己的独特完全释放,给别人一个完全不同的自己。     

A simple microscopy assay to teach the processes of phagocytosis and exocytosis

Phagocytosis and exocytosis are two cellular processes involving membrane dynamics. While it is easy to understand the purpose of these processes, it can be extremely difficult for students to comprehend the actual mechanisms. As membrane dynamics play a significant role in many cellular processes ranging from cell signaling to cell division to organelle renewal and maintenance, we felt that we needed to do a better job of teaching these types of processes. Thus, we developed a classroom-based protocol to simultaneously study phagocytosis and exocytosis in Tetrahymena pyriformis. In this paper, we present our results demonstrating that our undergraduate classroom experiment delivers results comparable with those acquired in a professional research laboratory. In addition, students performing the experiment do learn the mechanisms of phagocytosis and exocytosis. Finally, we demonstrate a mathematical exercise to help the students apply their data to the cell. Ultimately, this assay sets the stage for future inquiry-based experiments, in which the students develop their own experimental questions and delve deeper into the mechanisms of phagocytosis and exocytosis.     

‘We're Going to Make You Popular': Popular Collections in the Modern Academic Law Library

One way to promote the relevancy of an academic law library is to create a special collection that generates interest in the patron base; a popular collection is a viable way of reinventing a law library's image in the hearts and minds of the law school community. Popular collections have been championed by general academic librarians because they promote reading and literacy, the use of the library as a place, and such collections represent the shift toward a user focused library model. Using data collected from interviews and analysis of collection development policies this article presents models of popular collections currently in use at academic law libraries, as well as considerations for the creation of such collections.     

Teaching thinking: the case for principles

Abstract

This paper reviews the situation with regard to the teaching of thinking skills as part of the taught curriculum. The case is made for direct teaching of cognitive skills both to meet the particular learning difficulties of children with special educational needs and also to enhance the learning and thinking of all children. The dangers of ‘recipe’ approaches to teaching this aspect of the curriculum are discussed and a ‘principles’ approach is advocated. Some principles are then described which may be used to underpin the designing of problem‐solving activities, through which thinking skills can be taught across the curriculum.     

Nothing about us without us! Youth-led solutions to improve high school completion rates

This Youth Participatory Action Research (YPAR) study represents a collaboration with six students from alternative education to inquire about the experiences of vulnerable youth – students in alternative education and youth who have dropped out of school. Utilizing the Enhanced Critical Incident Technique, youth researchers asked their peers what helped and hindered their retention and success in mainstream and alternative education. Youth researchers engaged in authentic participation and took part in the iterative phases of YPAR – critical reflection and social action. Their involvement empowered them to advocate for their peers by disseminating the results and recommendations to key stakeholders within the community. Youth researchers conducted semi-structured interviews with 18 participants. Overall, the findings show that relationships with staff and peers, flexibility, psychosocial and academic supports, and personal circumstances are vital in helping vulnerable students succeed in school. Engagement in YPAR provided insight into working with vulnerable youth in a manner that promotes agency and social change within educational institutions.     

Early years curriculum: funds of knowledge as a conceptual framework for children’s interests

Children’s interests are frequently cited as a source of early‐years curricula. Yet, research has rarely considered the nature of these interests beyond the play‐based environment of early‐childhood education. This paper reports findings from a qualitative, interpretivist study in two early childhood settings in Aotearoa/New Zealand. Using participant observation, interviews, and documentation, the study examined children’s interests and teachers’ engagement with these in curriculum interactions. Evidence suggested children’s interests were stimulated by their ‘intent participation’ in family and community experiences and encapsulated in the notion of ‘funds of knowledge’. The concept of funds of knowledge provides a coherent analytic framework for teachers to recognize children’s interests and extend teachers’ curriculum planning focus beyond that of a child‐centred play‐based learning environment.     

Molecular biology and immunology of fungal allergens

Fungi are non-chlorophyllus microorganisms, which constitutes the main source of outdoor and indoor allergens. The antigens present in the spores and fragments of hyphae induce allergic responses in sensitized patients. The frequently recognized fungi associated with asthma include Alternaria, Cladosporium, Aspergillus, and Penicillium. With the advent of molecular biology techniques a number of fungal genes encoding relevant allergens have been cloned and the expressed allergens purified and characterized. In this review, we have presented the recent developments, where recombinant allergens have been used in the precise diagnosis of fungal allergy. We have also discussed the role played by these allergens and the T- and B-cell epitopes in the immune mechanism in fungal allergy.