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Alpha-1-antitrypsin deficiency is a hereditary disease leading to hepatitis and cirrhosis. It is the most common genetic cause of liver disease in children which must inherit the tendency from both parents to develop. It acquires the highest priority in the differential diagnosis in a child with chronic liver disease. In this case report we substantiate the role of serum protein electrophoresis, in diagnosing alpha-1-antitrypsin deficiency.  相似文献   
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This review presents a conceptual framework and supporting evidence that links impaired motor control after sport-related concussion(SRC)to increased risk for musculoskeletal injury.Multiple studies have found that athletes who are post-SRC have higher risk for musculoskeletal injury compared to their counterparts.A small body of research suggests that impairments in motor control are associated with musculoskeletal injury risk.Motor control involves the perception and processing of sensory information and subsequent coordination of motor output within the central nervous system to perform a motor task.Motor control is inclusive of motor planning and motor learning.If sensory information is not accurately perceived or there is interference with sensory information processing and cognition,motor function will be altered,and an athlete may become vulnerable to injury during sport participation.Athletes with SRC show neuroanatomic and neurophysiological changes relevant to motor control even after meeting return to sport criteria,including a normal neurological examination,resolution of symptoms,and return to baseline function on traditional concussion testing.In conjunction,altered motor function is demonstrated after SRC in muscle activation and force production,movement patterns,balance/postural stability,and motor task performance,especially performance of a motor task paired with a cognitive task(i.e.,dual-task condition).The clinical implications of this conceptual framework include a need to intentionally address motor control impairments after SRC to mitigate musculoskeletal injury risk and to monitor motor control as the athlete progresses through the return to sport continuum.  相似文献   
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The Sterkfontein Caves UNESCO World Heritage site represents one of South Africa’s most valuable cultural heritage resources and is one of the world’s most prolific palaeoanthropological sites with its fossiliferous deposits spanning the last 3.5 million years. One of the most famous fossil-bearing deposits at Sterkfontein is the 2.5 million-year-old Member 4. This is the world’s richest Australopithecus-bearing deposit and has yielded iconic fossils like StS 5 – Mrs Ples, StW 53, two partial skeletons, and two species of Australopithecus. After 80 years of research, Member 4 continues to provide crucial evidence for human origins research. Over the last 35 years, since excavation of the Member 4 started exposing the walls of the deposit, their deterioration has been accelerating. The implications of this deterioration and impending collapse are severe, not only from a palaeoanthropological perspective but also a heritage management point of view. This article focuses on our efforts to conserve the deteriorating areas of the Member 4 excavation site. The project required the development of a comprehensive set of strategies that had to be adapted to the specific requirements of the national and local heritage management agencies and remain sensitive to ongoing research programmes. The strategy developed included: multiscale integrative documentation of the exposed deposits; comprehensive, independent but cohesive stabilization of the different components of the deposit while maintaining visibility for ongoing and future research; and installation of stabilization infrastructure that could be adapted to the long-term conservation excavation plan while maintaining deposit integrity and site safety.  相似文献   
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This study examines year-by-year correlations between Freedom House and Reporters Sans Frontières' (RSF) press freedom scores for countries over a 13-year period (2002–2014). The goal of the study is to test the hypothesis that, further into the age of digital disclosure, as press abuses and harassment of journalists are more widely reported, press freedom ranking systems are gradually becoming more precise and, therefore, correlations between the two indices will strengthen over time. To further assess concurrent validity of the indices, correlations between both indices and scores on the United Nations Human Development Index are also provided. The study also examines changes in the indices' rankings of countries over time within six world regions: the Middle East and North Africa, the Americas, Western Europe, Eastern Europe/Central Asia, Sub-Saharan Africa, and Asia. In so doing, this study adds a degree of understanding to the validity of two press freedom indices that are routinely cited in journalistic reportage and trade journals, as well as many scholarly publications. Results suggest that the two organizations' scoring of press freedom has become significantly more correlated in the years 2002–2014, and the primary cause of the increased agreement is that RSF's ratings became substantially more aligned with Freedom House's scores during this period. Both indices' ratings are significantly correlated with countries' United Nations Human Development Index scores.  相似文献   
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Courses: Interpersonal Communication, Health Communication, Intercultural Communication

Objectives: After completing this semester-long activity students, should be able to (1) apply course concepts (i.e., stereotypes, identity, listening, language, and conflict) to diverse real-world scenarios; (2) explain the utility of intergroup contact theory in relationship to communication and social diversity; (3) critically reflect on social diversity explored through communication behaviors; and (4) develop communication competence toward diverse others, specifically persons with disabilities (PWDs).  相似文献   
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ABSTRACT

Service blueprinting is a method for designing, assessing, and improving services. This article provides a practical overview of the service blueprinting process for library technology services. We begin by outlining the recent conversation around library technologies, service design, and service blueprinting. We then detail an iterative case study for the creation process of a service blueprint, followed by a discussion of the service insights and improvements that resulted from this activity. We conclude by offering a set of recommendations for creating and analyzing service blueprints. Ultimately, the service blueprint is a useful tool for understanding the operation of a service, and for situating that service within a broader and interconnected library ecosystem.  相似文献   
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