A Virtual Notebook for biomedical work groups

During the past several years, Baylor College of Medicine has made a substantial commitment to the use of information technology in support of its corporate and academic programs. The concept of an Integrated Academic Information Management System (IAIMS) has proved central in our planning, and the IAIMS activities that we have undertaken with funding from the National Library of Medicine have proved to be important extensions of our technology development. Here we describe our Virtual Notebook system, a conceptual and technologic framework for task coordination and information management in biomedical work groups. When fully developed and deployed, the Virtual Notebook will improve the functioning of basic and clinical research groups in the college, and it currently serves as a model for the longer-term development of our entire information management environment.     

Dynamic optimal control model for profit maximization of software product under the influence of promotional effort

In this paper, a decision model is presented for the sales of software product to determine the profit and marketing policy under the influence of promotional efforts. The paper focuses on dependence of the optimal profit on the promotional efforts when there is diffusion effect of demand on the sales function. An elaborate optimization policy considering the dynamic nature of production cost function is proposed and numerical example is illustrated. The paper also studies the behavior of the future profit and its impact on profit maximization model by considering the constant price during the entire planning horizon. The experimental results greatly help us to identify the contributions of each selected parameter and its weight. Some conclusions, limitations of this study and future direction are also discussed.     

Inter-organizational knowledge integration in Collaborative NPD projects: evidence from the aerospace industry

This paper aims to analyse the practice of knowledge integration (KI) in Collaborative New Product Development (Co-NPD) projects involving multiple partners in an aerospace network. On the basis of a pragmatic approach, a multiple-case study is developed focusing on two Italian aerospace companies involved in a research project aimed to define methodologies and technologies for knowledge collaboration in NPD. Data are gathered with a triangulation technique merging official documents and open-ended and closed-ended interviews administered in the companies’ sites and involving managers, engineers and employees. The paper proposes a systematic treatment of the KI practice describing the types of knowledge, strategies, barriers and intellectual property policies for KI at inter-organizational level. The findings provide insights to address NPD models for aerospace networks where the complexity and value of codified knowledge coming from external sources requires adequate treatments and security standards.     

Investigation on CO(2) laser irradiation inducing glass strip peeling for microchannel formation

The study investigates the use of CO₂ laser to induce glass strip peeling off to form microchannels on soda lime gass substrate. The strip peeling exhibits a strong dependence on the energy deposition rate on the glass surface. In spite of the vast difference in the combination of laser power and scanning speed, when the ratio of the two makes the energy deposition rate in the range 3.0-6.0 J/(cm² s), the temperature rising inside glass will be above the strain point and reach the softening region of the glass. As a result, glass strip peeling is able to occur and form microchannels with dimensions of 20-40 μm in depth and 200-280 μm in width on the glass surface. Beyond this range, higher energy depsotion rate would lead to surface melting associated with solidification cracks and lower energy deposition rate causes the generation of fragment cracks.     

Incidence and risk for traumatic and overuse injuries in top-level road cyclists

All traumatic and overuse injuries occurring during an average period of 4 years (2002/09) in a group of 51 currently active road top-level cyclists were retrospectively registered through clinical interviews. Average age was 25.8 years. Average training and competition period was 28.3 ± 2.4 h a week. Only 8 cyclists (15.6%) were completely free from lesions during the period of study. The remaining 43 cyclists suffered a total of 112 lesions; however, 9 out of these were unrelated to their cycling practice. These 103 cycling-related injuries include 50 (48.5%) traumatic and 53 (51.5%) overuse injuries. Twenty-eight fractures were reported, the clavicle being the most frequently affected bone (11 cases). The 68.5% of overuse injuries were located in the lower limbs. Most overuse injuries (89.6%) occurred during the training period. According to the injury abbreviated scale (AIS), severe lesions were only found in 4 cases (8% of traumatic injuries). Overall injury rates were 0.50 per racer/year, 2.02 per studied racer, and 0.007 per 1000 km of training and competition. Active professional top-level cyclists are exposed to a high injury risk. According to the scarce previously published data the current study provides relevant information on the injury occurrence of still active top-level road cycling.