New Frontiers in Visual Search: An Exploratory Study in Live Tennis Situations

This study compares the motor skills and physical fitness of school-age children (6-12 years) with visual impairments (VI; n = 60) and sighted children (n = 60). The relationships between the performance parameters and the children's body composition are investigated as well as the role of the severity of the impairment. The degree of VI did not differentially affect the outcomes. Compared to their sighted peers, the children with VI scored lower on the locomotor and object control skills as assessed with the Test of Gross Motor Development-2, and the physical fitness (Eurofit) parameters of plate tapping, the standing broad jump, the modified 5 × 10-m shuttle run, and 20-m multistage shuttle run (20-MST). Their body mass and body fat indexes were inversely correlated with the standing broad jump and the 20-MST, but positively correlated with handgrip strength. Moreover, significant inverse correlations were found between their locomotor and object control skills on the one hand and plate tapping and the 5 × 10-m shuttle run on the other hand. Given the relatively high proportion (25%) of overweight/obese children within the VI sample, educators are recommended to promote health-related activities and help enhance motor skills in this population.     

Do the effects of early severe deprivation on cognition persist into early adolescence? Findings from the English and Romanian adoptees study

Cognitive outcomes at age 11 of 131 Romanian adoptees from institutions were compared with 50 U.K. adopted children. Key findings were of both continuity and change: (1) marked adverse effects persisted at age 11 for many of the children who were over 6 months on arrival; (2) there was some catch-up between ages 6 and 11 for the bottom 15%; (3) there was a decrease of 15 points for those over 6 months on arrival, but no differentiation within the 6-42-month range; (4) there was marked heterogeneity of outcome but this was not associated with the educational background of the adoptive families. The findings draw attention to the psychological as well as physical risks of institutional deprivation.     

Fault-tolerant sensorless control of wind turbines achieving efficiency maximization in the presence of electrical faults

This paper proposes a sensorless fault-tolerant control strategy solving the tracking problem of the maximum delivered power characteristic for a wind energy conversion system equipped with a permanent magnet synchronous generator. A previously published control scheme ensuring the maximum power efficiency of the wind turbine, not requiring feedback information about rotor speed and position, and about wind velocity, is here extended to make the control scheme fault-tolerant with respect to possible electrical faults affecting the equations of the permanent magnet synchronous generator (PMSG) in the original (α, β) frame. The control law is based on a number of interconnected nonlinear observers. Closed loop asymptotic vanishing of the observation errors is proved. The proposed control solution has been validated on the National Renewable Energy Laboratory (NREL) 5-MW three-blade wind turbine model.     

Muscle force characteristics of male and female collegiate cross-country runners during overground running

ABSTRACT

Males and females demonstrate unique running mechanics that may contribute to sex-related differences in common running related injuries. Understanding differences in muscle forces during running may inform intervention approaches, such as gait retraining addressing muscle force distribution. The purpose of this study was to compare muscle force characteristics and inter-trial variability between males and females during running. Twenty female and 14 male collegiate cross-country runners were examined. Three-dimensional kinetic and kinematic data were collected during overground running and used to estimate muscle forces via musculoskeletal modelling. Principle components analysis was used to capture the primary sources of variance from the muscle force waveforms. The magnitude of the forces for the hamstrings, gastrocnemius, and soleus muscles were higher across the majority of stance in male runners regardless of footstrike pattern. Males also demonstrated greater inter-trial variability in the timing of the peak gluteus maximus force and the magnitude of local peaks in the gastrocnemius force waveform. Male and female collegiate cross-country runners appear to employ unique lower extremity muscle force characteristics during overground running.     

“P53 Codon 72 Single Base Substitution in Viral Hepatitis C and Hepatocarcinoma Incidences”

Viral infection with hepatitis C virus (HCV) has a high propensity in becoming chronic and it is the major cause of hepatocellular carcinoma (HCC) worldwide. This review was basically established to illustrate the putative role of the P53 gene Arg72Pro polymorphism on various cancer models and viral infections, focusing on HCV and HCC incidences. Authors studied the 72 G/C single base substitution of P53 gene at codon 72 using various polymorphic techniques. Intriguingly, authors investigated that the P53 codon 72 plays a crucial role as risk factor in several cancer models. Others found that there is no association between codon 72 genotypes and HCV disease severity or liver cancer. Moreover, the lack of a significant relationship between this polymorphism and risk of HCC shows that it does not predispose towards hepatocarcinogenesis and the frequent loss of the proline allele in HCV-associated carcinogenesis of the liver plays some critical role in hepatocarcinogenesis. Amazingly, there is a significant correlation between male homozygotes for P53 72Pro with HCV type 1b infection. However, there was no significant difference between the P53 polymorphism and HCV genotypes 2a and 2b. It was concluded that the P53 gene polymorphism at codon 72 has been investigated as potential risk factor in several cancer models and HCV infections.     

The effect of exercise interventions on resting metabolic rate: A systematic review and meta-analysis

ABSTRACT

The systematic review and meta-analysis evaluated the effect of aerobic, resistance and combined exercise on RMR (kCal·day^-1) and performed a methodological assessment of indirect calorimetry protocols within the included studies. Subgroup analyses included energy/diet restriction and body composition changes. Randomized control trials (RCTs), quasi – RCTs and cohort trials featuring a physical activity intervention of any form and duration excluding single exercise bouts were included. Participant exclusions included medical conditions impacting upon RMR, the elderly (≥65 years of age) or pregnant, lactating or post-menopausal women. The review was registered in the International Prospective Register of Systematic Reviews (CRD 42,017,058,503). 1669 articles were identified; 22 were included in the qualitative analysis and 18 were meta-analysed. Exercise interventions (aerobic and resistance exercise combined) did not increase resting metabolic rate (mean difference (MD): 74.6 kCal·day^-1[95% CI: ?13.01, 161.33], P = 0.10). While there was no effect of aerobic exercise on RMR (MD: 81.65 kCal·day^-1[95% CI: ?57.81, 221.10], P = 0.25), resistance exercise increased RMR compared to controls (MD: 96.17 kCal·day^-1[95% CI: 45.17, 147.16], P = 0.0002). This systematic review effectively synthesises the effect of exercise interventions on RMR in comparison to controls; despite heterogenous methodologies and high risk of bias within included studies.     

Career Academies: Effective Structures to Promote College and Career Readiness

Career academies promote smaller learning communities within high schools, creating personalized learning environments while promoting students’ readiness for college and careers. After describing the career academy structure, we present four research-based aspects that can assist school leaders and teachers in developing and implementing academies. We include practical examples from the Metro Nashville Public Schools, noting how educators have collaborated with civic agencies, businesses, and postsecondary partners to increase the graduation rate and improve student learning outcomes. Career academies can be effective in preparing students for college and careers, while also providing economic benefits to the community.