A comparative study on oxidative stress and antioxidant status in ischemic stroke patients with and without diabetes

The study was conducted to find out the extent of lipid peroxidation and antioxidant status in ischemic stroke patients (ISPs) with and without diabetes. Malondialdehyde (MDA) was studied as a marker of lipid peroxidation. Glutathione (GSH), uric acid and ceruloplasmin were estimated to study the antioxidant potential of ISPs. Significantly higher levels of MDA were found in both the groups of ISPs and the increase in MDA was more in ISPs without diabetes. GSH levels were decreased significantly in both the groups of ISPs and maximum decline was found in ISPs with diabetes. Uric acid levels were significantly increased in both the groups of ISPs. Ceruloplasmin levels were increased significantly in ISPs without diabetes, whereas its levels were slightly decreased in ISPs with diabetes. A negative correlation was found between MDA and the antioxidants GSH, uric acid and ceruloplasmin in ISPs with diabetes. This study suggests that there is an association between ischemic stroke and increased oxidative stress and the antioxidant potential is impaired in both the groups of ISPs with and without diabetes.     

Opposite Sides of the Same Coin? Exploring the Connections between School Absenteeism and Student Mobility

ABSTRACT

Mobile students and absent students are important subsets of at-risk students in schools and districts nationwide. As such, student mobility and school absenteeism are two challenges in K-12 education with significant policy and equity implications. Although both issues are at the nexus of schooling and society and there is an apparent overlap in the attributes of these student subgroups, school absenteeism and student mobility are often discussed in separate conversations. This article connects the two disparate literatures in hopes of forging stronger ties that may benefit policymakers, researchers, educators, and students. The limited empirical evidence is mixed but suggests that school absenteeism and student mobility are correlated and absenteeism plays a small mediating role in the relationship between student mobility and student outcomes. The reasons underlying student mobility and student absenteeism are interrelated but not all reasons are common. The overlapping causes of student mobility and chronic absenteeism indicate that economic and social circumstances are important underlying factors. In particular, poverty is a key shared reason for missing or switching schools. Although both phenomena contribute to disparities in educational opportunities, experiences, and outcomes, this study posits that changing schools and missing school provide instructive examples of how inequality in society may be reproduced in districts and schools. Recommendations to address both phenomena and directions for future research are discussed.     

The privatisation of public schooling in New Zealand

This paper examines recent privatisation practices in New Zealand public schooling. The standard political rhetoric is that free publicly provided schooling is guaranteed by statute. This position may be challenged by reference to two apparently insignificant practical examples of the way in which policy gives effect to privatisation in public schooling: (1) the commissioning of national assessment strategy policy advice, and (2) the award of contestable funding for the provision of support services to schools. It is argued that such practices advance neoliberal theories of schooling at the expense of the previous social democratic liberal settlement. The paper considers some possible consequences of increased privatisation of policy advice and service provision for understandings of and commitments to public schooling.     

Improving the learning of Boolean queries by means of a multiobjective IQBE evolutionary algorithm

The Inductive Query By Example (IQBE) paradigm allows a system to automatically derive queries for a specific Information Retrieval System (IRS). Classic IRSs based on this paradigm [Smith, M., & Smith, M. (1997). The use of genetic programming to build Boolean queries for text retrieval through relevance feedback. Journal of Information Science, 23(6), 423–431] generate a single solution (Boolean query) in each run, that with the best fitness value, which is usually based on a weighted combination of the basic performance criteria, precision and recall.     

Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report

Tumor lysis syndrome has been observed in patients with malignancies with high cellular burden and high cell turnover, tumor sensitive to therapy, especially after initiating medical treatment. It very rarely occurs spontaneously. The case described here is of 6 months male infant who presented with fever since 1 month and loose stools associated with blood since 15 days. The laboratory investigations showed lactate dehydrogenase (LDH) of 6,192 IU/L and serum uric acid 18.2 mg/dl along with pancytopenia. The infant presented with electrolyte abnormalities and renal failure.