Extending the hand of knowledge: promoting mobile technologies

The widespread use of handheld computers and other mobile devices in the healthcare environment and their potential for providing access to information has prompted health sciences librarians everywhere to learn more about this technology. Early in 2001, the Health Sciences Library (HSL) at the University of North Carolina at Chapel Hill began exploring ways to support mobile computing. This paper describes the four basic approaches taken by the librarians that helped establish the HSL as a leader in the area of mobile technologies.     

Toward multimodal inquiry: opportunities,challenges and implications of multimodality for research and scholarship

In this article, we suggest that we are witnessing a challenge to the hegemony of text-based knowledge in academic scholarship, brought about by newly available modes of expression, and a cultural shift in our notions of reading and writing, authorship, and networked knowledge production. The central question we address here concerns the implications of widening our ideas of acceptable forms of inquiry, analysis and representation in academic scholarship. As a collective of scholar-practitioners exploring new modes of expression and working both within and outside the formal structures of academia, we argue for the increasing significance of multimodal research in the contemporary context of academic inquiry. By more equitably valuing different ways of thinking, knowing and communicating, multimodal research can facilitate wider and more diverse participation in the production of knowledge, offer a more nuanced and ethical mode of inquiry, emphasize different ways of knowing and connecting, and make scholarship more broadly accessible beyond academic contexts. Here, we analyze the key opportunities facilitated by multimodal inquiry, as well as the obstacles that stand in the way of a wider adoption of this type of research in higher education.     

Language and reading impairments are associated with increased prevalence of non-right-handedness

Handedness has been studied for association with language-related disorders because of its link with language hemispheric dominance. No clear pattern has emerged, possibly because of small samples, publication bias, and heterogeneous criteria across studies. Non-right-handedness (NRH) frequency was assessed in N = 2503 cases with reading and/or language impairment and N = 4316 sex-matched controls identified from 10 distinct cohorts (age range 6–19 years old; European ethnicity) using a priori set criteria. A meta-analysis (N_cases = 1994) showed elevated NRH % in individuals with language/reading impairment compared with controls (OR = 1.21, CI = 1.06–1.39, p = .01). The association between reading/language impairments and NRH could result from shared pathways underlying brain lateralization, handedness, and cognitive functions.     

Growth in biomedical publications and scientific institutions in the Emirates (1998–2004): an Arabian renaissance?

OBJECTIVES: The United Arab Emirates is witnessing a rapid development in population and infrastructure, leading to an expansion in the educational field and the health care system, including universities, hospitals and research institutes. One potential outcome of this development is an increase in biomedical research publications. This was examined in this study. METHOD: Searches were made of three databases; PubMed, Current Contents and embase. All records from these databases related to the Emirates were downloaded and cross-referenced. Duplications were removed as well as erroneous records. A total of 1369 publications during 1998-2004 were obtained. RESULTS: Analysis of these records revealed that the Faculty of Medicine and Health Sciences, located at the federal University, was responsible for 48% of all biomedical publications. All hospitals together accounted for 24%, while other universities and other research institutes accounted for 13 and 14% respectively. Further analysis revealed that there had been no further growth in the number of publications since 1998. This is in contrast to the increasing number of institutions that have been set up in the 1998-2004 period; from 29 to 112. CONCLUSION: The Emirates are witnessing a rapid development in universities, colleges, hospitals and research centres. The ratio of publications, as yet, has not kept up with this development. The enormous growth in institutes, however, may, in time, herald an Arabian renaissance in scientific activity and related publications.     

Developing participation opportunities for young people with disabilities? Policy enactment and social inclusion in Australian junior sport

Abstract

Interventions aimed at increasing the participation of young people with disabilities in recreational sport have had mixed success. The authors draw on in-depth interviews with representatives from State Sporting Associations, local government officers and volunteers within community sports clubs in Victoria, Australia, to examine why some sports clubs are unable or unwilling to translate policy ambitions into practice. The findings indicate how by framing disability provision as ‘too difficult’, ‘not core business’ and antithetical to competitive success, community sports clubs are able to resist policy ambitions to modify existing structures and develop more inclusive practice. Greater priority needs to be given to transformational inclusion objectives and challenging ableism if clubs are to structurally progress the development of participation opportunities for young people with disabilities.     

Denying Genetic Causality

This edited volume of essays presents a countermainstream view against genetic underpinnings for cancer, behavior, and psychiatric conditions.This edited volume is a project from the Council of Responsible Genetics, a private organization based in Cambridge, Massachusetts, whose mission, as stated on its website, includes as one of several goals to “expose oversimplified and distorted scientific claims regarding the role of genetics in human disease, development and behavior.” This book represents such an effort. Editors Krimsky and Gruber are chair and president/executive director, respectively, of the organization and appear to have solicited contributions to the book from affiliates and other colleagues. Fewer than half of the 16 chapters are written by active laboratory scientists, however, and as a result, the book suffers from arguments clouded by imprecise use of terminology and preconceptions about genes and their functions. One might consider this book, or parts thereof, for an advanced undergraduate genetics class in which positions counter to the mainstream scientific view are presented and evaluated, and in which students are challenged to critically assess the quality of support for all arguments.The general theme of this book is to question the role of genes (and reproducible molecular mechanisms, more broadly) in cancer, behavior, psychiatric disorders, evolution, and other phenomena. One chapter promotes the tissue organization field theory (TOFT) against the somatic mutation theory of cancer. TOFT was proposed by the chapter authors in 2011 (Soto and Sonnenschein, 2011 ) but has not found traction and has garnered little attention beyond an initial refutation (Vaux, 2011 ). The authors assert that cancer is a disease of development and tissue repair primarily from environmental exposures and independent of genetic changes. Most cancer researchers agree that environmental factors can trigger cell growth but that ensuing mutations complete the picture in the genesis of malignancies. This chapter would be a good starting point from which one could assign students to explore papers cited in the Cancer Genome Atlas database, a growing resource compiling cancer genome data and subsequent validation in other systems of the effects of mutations found. In another chapter, a nonscientist author asserts that “in only a small percentage of cases are genes notable contributors to breast cancer,” implying imprecisely that only rare inherited cancer predisposition is genetic, when in fact cancer stemming from somatic mutations is also gene based. To assert that cancer stems only from environmental effects, to the exclusion of genes, overlooks the intertwining of the two arenas—radiation induces somatic mutations, for example, and estrogen mimics trigger cell division, which sets the stage for additional new mutations during DNA replication. Open in a separate windowOther sections of the book argue a lack of evidence for genetic influence on behaviors and psychiatric conditions. One chapter centers on several refuted ideas of biology and behavior (for example XYY and monoamine oxidase genotypes associated with aggression), with the intended implication that all other biological connections to behavior must be suspect. A chapter on autism accepts but downplays a partial role of genetics in the disorder, while emphasizing environmental exposures. Students exploring this topic could examine the growing literature on de novo mutations found in autism patients (Huguet et al., 2013 ), among other autism studies, to see how interlocking causes of the disorder might best explained by the available data. In the context of disorders such as schizophrenia, the book does not acknowledge or address the literature reporting genetic associations with psychiatric predispositions. In a troubling instance, a cited reference is misrepresented as refuting a genetic connection to schizophrenia; the reference in question (Collins et al., 2012 ) actually reports genome-wide association studies showing linkage of schizophrenia to particular loci (just not to the genes originally suspected). The same research group the previous month reported copy number variations associated with schizophrenia (Kirov et al., 2012 ), but this finding was not cited. Psychiatric genetics is a rich area for students to explore, and the contrarian viewpoint of the book can provide a starting point to trigger students’ delving into the literature.Genetic Explanations: Sense and Nonsense includes two chapters with assertions counter to the neo-Darwinian synthesis of evolution. One claims, fairly misleadingly, that “a growing number of evolutionary biologists … believe that macroevolution was the result of mechanisms other than natural selection.” Another states that “not genomic DNA but epigenetic environmental influences … overwhelmingly affect our health and well being.” The idea that gene regulation via environmental and epigenetic effects is somehow not reducible to genes (and that genes are therefore not central to evolution) would be an interesting subject for students to explore in the literature to see what the data actually support.This book is recommended only for use in advanced classes centered on weighing evidence and dissecting arguments in scientific controversies. The book''s countermainstream assertion of a lack of significant genetic connection to cancer, autism, schizophrenia, and other phenomena provides multiple opportunities for students to explore the scientific literature surrounding such genetic connections.     

A Theoretical Model for Preparing Incarcerated Youth for Careers in an Increasingly Technological World: Computational Logic as a Vehicle for Improving Human Decision-making Skills

Most youth in juvenile delinquent systems end up incarcerated due in part to poor decision-making skills. This study describes a theoretical framework undergirding the relationships across delinquency, learning climate, decision-making, and computational logic. This framework will inform a team of educators, criminologists, and psychologists, and their peers in computer science and mathematics, instructional software design, and content experts as they build and test an innovative instructional model for youth in secure care settings. The goal of the system is to improve human decision-making skills, while preparing youth for further education potentially leading to careers in STEM fields.     

The influence of grandparents’ social class on children’s aspirations

Social class mobility from grandparent to grandchild is a relatively neglected topic. Grandparents today are often healthier and more active, and have longer relationships with their grandchildren than in previous generations. We used data from the UK’s Millennium Cohort Study (n = 8570) to investigate the influence of maternal and paternal grandparents’ social class on the aspirations of children at age seven. Using path analysis and controlling for family income, mother’s and father’s education, lone motherhood, and child’s ethnicity and gender, we found very small direct effects from the paternal grandmother’s social class to the grandchild’s classed aspirations, and small, indirect effects, via parents’ class, of grandparents’ class on child’s classed aspirations. Multi-group analyses found few differences by ethnicity and gender. There was no evidence that, at this age, mixed-class parentage raises the aspirations of working-class children (the ‘sunken middle-class’ hypothesis).