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711.
Four questions are presented: What are the historical roots of motor development; How can motor development be characterized; How should motor development be conceptualized; and How should motor development be organized? A brief history presents the psychological roots of motor development and emphasizes the individual researchers who have created the area of motor development since the 1960s. Motor development is characterized as a composite of the researchers, knowledge, application of knowledge, systems for delivering knowledge, and graduate programs in motor development. Motor development should be a perspective rather than a structure or subdiscipline. All courses in human movement should be taught from a developmental perspective, research should be done within the appropriate subdiscipline, and some of that research should be developmental. Motor development will be best served if researchers align with scientists within the subdisciplines and share developmental information in cross-disciplinary groups.  相似文献   
712.
Religious education has changed considerably over the 100 years of the Religious Education Association (REA); urgency has increased for human communities to honor diversity. The focus of this article is realities, visions, and promises of cultural diversity. The article includes an overview of REA's recent history, exemplifying its efforts and limitations in diversity. It then turns to five commentaries on a multicultural future, drawing on autobiographical analysis, religious and educational literature, and empirical study. Authors explicate and argue for: engaging in post-colonial analysis, de-centering assumptions, searching for a story to claim, taking time, and entering deep waters.  相似文献   
713.
Background:?Twenty-first-century undergraduates often find eighteenth-century culture difficult to access and, influenced by popular assumptions about the period in current media theory, characterise the century as individualist, underestimating the cultural significance of social networking in literary and political history.

Purpose:?This study set out to teach the history of social networking as culturally significant in the production of literary texts during the eighteenth century as well as to demonstrate the intellectual and compositional potential of today's social networking technologies. A virtual reconstruction of eighteenth-century London in Second Life and a semester project requiring the student recreation of 3D social spaces like coffee houses and gardens tested the uses of social networking tools to teach research methods and build disciplinary knowledge.

Sources of evidence:?Evidence of student learning outcomes is provided by three undergraduate courses in eighteenth-century culture, with 68 students total, that participated in Second Life re-enactment assignments on Island 18 during the autumn of 2008 and spring of 2009. The results of the student projects as well as student-completed evaluations and self-reflective essays about their experiences using virtual reality to learn history are consulted. Theoretical evidence by scholars of new media, eighteenth-century history and education provides a background for the study's impetus and goals.

Main argument:?Virtual reality provides an opportunity for educators of eighteenth-century culture to teach students, through the reflective and critical use of the social networking tools Second Life makes available, the significance of social networking in the history of ideas of that period. We dismantle the generalisations of scholars working outside of the period who characterise the eighteenth century as a solely individualist era, during which singular genius defined the enlightenment and propose a more culturally viable model of social collaboration, supported by communication technologies not so different from twenty-first-century instant messaging, blogging, twittering and emailing.

Conclusions:?Contrary to the recent findings of humanities educators who claim that digital social networking tools are distracting undergraduates from more valuable academic writing, we find that a task-oriented semester project requiring the construction of 3D historical social spaces teaches investigative research skills, deterritorialises disciplinary knowledge and promotes revision as an ongoing process.  相似文献   
714.
This paper argues that contemporary understandings of cosmopolitan literature are significantly limited by their dependence on sympathetic attachments as constitutive of cosmopolitan practice. I trace a genealogy of the connection between sympathy, cosmopolitanism, and the novel that extends from Adam Smith and Immanuel Kant to Martha Nussbaum and Kwame Anthony Appiah, in order to contend that contemporary models of cosmopolitan reading rely on problematically normative definitions of the ‘human’. J.M. Coetzee's Boyhood, I propose, suggests an alternative model of cosmopolitan reading that neither equates sympathy with humanity, nor precludes those who ‘feel apart’ from participation in cosmopolitan community.  相似文献   
715.
Circulating tumor cells (CTCs) are prognostic markers for the recurrence of cancer and may carry molecular information relevant to cancer diagnosis. Dielectrophoresis (DEP) has been proposed as a molecular marker-independent approach for isolating CTCs from blood and has been shown to be broadly applicable to different types of cancers. However, existing batch-mode microfluidic DEP methods have been unable to process 10 ml clinical blood specimens rapidly enough. To achieve the required processing rates of 106 nucleated cells/min, we describe a continuous flow microfluidic processing chamber into which the peripheral blood mononuclear cell fraction of a clinical specimen is slowly injected, deionized by diffusion, and then subjected to a balance of DEP, sedimentation and hydrodynamic lift forces. These forces cause tumor cells to be transported close to the floor of the chamber, while blood cells are carried about three cell diameters above them. The tumor cells are isolated by skimming them from the bottom of the chamber while the blood cells flow to waste. The principles, design, and modeling of the continuous-flow system are presented. To illustrate operation of the technology, we demonstrate the isolation of circulating colon tumor cells from clinical specimens and verify the tumor origin of these cells by molecular analysis.  相似文献   
716.
Abstract

Ingesting carbohydrate plus protein following prolonged exercise may restore exercise capacity more effectively than ingestion of carbohydrate alone. The objective of the present study was to determine whether this potential benefit is a consequence of the protein fraction per se or simply due to the additional energy it provides. Six active males participated in three trials, each involving a 90-min treadmill run at 70% maximal oxygen uptake (run 1) followed by a 4-h recovery. At 30-min intervals during recovery, participants ingested solutions containing: (1) 0.8 g carbohydrate · kg body mass (BM)?1 · h?1 plus 0.3 g · kg?1 · h?1 of whey protein isolate (CHO-PRO); (2) 0.8 g carbohydrate · kg BM?1 · h?1 (CHO); or (3) 1.1 g carbohydrate · kg BM?1 · h?1 (CHO-CHO). The latter two solutions matched the CHO-PRO solution for carbohydrate and for energy, respectively. Following recovery, participants ran to exhaustion at 70% maximal oxygen uptake (run 2). Exercise capacity during run 2 was greater following ingestion of CHO-PRO and CHO-CHO than following ingestion of CHO (P ≤ 0.05) with no significant difference between the CHO-PRO and CHO-CHO treatments. In conclusion, increasing the energy content of these recovery solutions extended run time to exhaustion, irrespective of whether the additional energy originated from sucrose or whey protein isolate.  相似文献   
717.

Reduced feedback during practice has been shown to be detrimental to movement accuracy in children but not in young adults. We hypothesized that the reduced accuracy is attributable to reduced movement parameter learning, but not pattern learning, in children. A rapid arm movement task that required the acquisition of a motor pattern scaled to specific spatial and temporal parameters was used to investigate the effects of feedback (FB) frequency (100% vs. 62% faded) on motor learning differences between 19 school-age children and 19 young adults. Adults and children practiced the task for 200 trials under the 100% or faded FB condition on Day 1 and returned on Day 2 for a no-FB retention test. On the retention test, children who practiced with reduced feedback performed with greater temporal parameter errors, but not pattern error, than children who received frequent feedback. Motor skill learning in children is influenced by feedback frequency during practice that affects parameter learning but not pattern learning.  相似文献   
718.
719.
Regression mixture models are a new approach for finding differential effects which have only recently begun to be used in applied research. This approach comes at the cost of the assumption that error terms are normally distributed within classes. The current study uses Monte Carlo simulations to explore the effects of relatively minor violations of this assumption, the use of an ordered polytomous outcome is then examined as an alternative which makes somewhat weaker assumptions, and finally both approaches are demonstrated with an applied example looking at differences in the effects of family management on the highly skewed outcome of drug use. Results show that violating the assumption of normal errors results in systematic bias in both latent class enumeration and parameter estimates. Additional classes which reflect violations of distributional assumptions are found. Under some conditions it is possible to come to conclusions that are consistent with the effects in the population, but when errors are skewed in both classes the results typically no longer reflect even the pattern of effects in the population. The polytomous regression model performs better under all scenarios examined and comes to reasonable results with the highly skewed outcome in the applied example. We recommend that careful evaluation of model sensitivity to distributional assumptions be the norm when conducting regression mixture models.  相似文献   
720.
The purpose of this study was to explore patronage and usage of the children’s section of a public library. Patrons of the children’s section of a public library in a small Northern Arizona city were observed for a total of 24 h over 12 sessions. Analytic induction was used to formulate categories based on field notes made during these observations. An observation of a story time session was also conducted. Data from an interview with a librarian was triangulated with observational data. In terms of patronage, the clear majority of parents/adult caregivers accompanying a child or children to the children’s section were observed to be female and speaking English. In terms of usage, the following three categories of early learning were identified from the data: early literacy learning; learning how to use a library; and other developmentally appropriate learning. Study results offer insight into both the role of females in the intergenerational transmission of literacy and the rich learning young children experience at the library. At a time of library cutbacks and closures across the United States, this study speaks to the continued relevance of the children’s section of the public library in providing free early learning experiences during the pivotal birth to five age range.  相似文献   
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