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741.
742.
Katherine Hallemeier 《Culture, Theory & Critique》2013,54(1):88-101
This paper argues that contemporary understandings of cosmopolitan literature are significantly limited by their dependence on sympathetic attachments as constitutive of cosmopolitan practice. I trace a genealogy of the connection between sympathy, cosmopolitanism, and the novel that extends from Adam Smith and Immanuel Kant to Martha Nussbaum and Kwame Anthony Appiah, in order to contend that contemporary models of cosmopolitan reading rely on problematically normative definitions of the ‘human’. J.M. Coetzee's Boyhood, I propose, suggests an alternative model of cosmopolitan reading that neither equates sympathy with humanity, nor precludes those who ‘feel apart’ from participation in cosmopolitan community. 相似文献
743.
This paper examines the existing literature on new technology-based firms in an attempt to understand how such companies contribute to the vitality of an economy and to see which variables are critical in enabling them to do so. From recent research efforts, we have drawn together a set of hypotheses and organized them around four central questions: (1) What do new firms contribute to the economy? (2) What factors contribute to the success of such enterprises? (3) In what cultural contexts do new businesses succeed? and (4) Which government policies are effective in stimulating and supporting new companies? We found that existing studies suggest (1) that new technology-based firms contribute significantly to an economy in terms of exports, employment, taxes paid, research and development, and innovations; (2) that the founders of these new businesses tend to have a strong entrepreneurial heritage, a development- rather research-oriented background, and a high need to achieve and are young and highly educated; (3) that sector differences may be a more important influence on company location than are regional policies; and (4) that no one government program has proven itself to be more than marginally successful in stimulating industrial innovation. 相似文献
744.
The Urban Review - This testimonio examines how a 3rd grade bilingual teacher unpacks the learning process as it relates to her agency in implementing culturally relevant (Ladson-Billings, Am Educ... 相似文献
745.
746.
Sarah J. Reiser Katherine A. McMillanKristi D. Wright Gordon J.G. Asmundson 《Child abuse & neglect》2014
Childhood experiences are thought to predispose a person to the development of health anxiety later in life. However, there is a lack of research investigating the influence of specific adverse experiences (e.g., childhood abuse, household dysfunction) on this condition. The current study examined the cumulative influence of multiple types of childhood adversities on health anxiety in adulthood. Adults 18–59 years of age (N = 264) completed a battery of measures to assess adverse childhood experiences, health anxiety, and associated constructs (i.e., negative affect and trait anxiety). Significant associations were observed between adverse childhood experiences, health anxiety, and associated constructs. Hierarchical multiple regression analysis indicted that adverse childhood experiences were predictive of health anxiety in adulthood; however, the unique contribution of these experience were no longer significant following the inclusion of the other variables of interest. Subsequently, mediation analyses indicated that both negative affect and trait anxiety independently mediated the relationship between adverse childhood experiences and health anxiety in adulthood. Increased exposure to adverse childhood experiences is associated with higher levels of health anxiety in adulthood; this relationship is mediated through negative affect and trait anxiety. Findings support the long-term negative impact of cumulative adverse childhood experiences and emphasize the importance of addressing negative affect and trait anxiety in efforts to prevent and treat health anxiety. 相似文献
747.
Doug Kirby transformed the field of sex education by conducting rigorous research that led to new, critical insights about ways to strengthen programmes, evaluation and policies related to sexual health throughout the world. Throughout his career, Kirby was meticulous in compiling evidence and translating findings into actionable recommendations for interventions, research and policy. He published more than 150 scientific articles, book chapters and monographs that have been widely cited and more than 900,000 copies of his publications have been distributed. Kirby's impact has been recognised with awards from numerous professional organisations and his unique and powerful scientific voice is greatly missed by his colleagues and friends. 相似文献
748.
Sangjo Shim Katherine Stemke-Hale Apostolia M. Tsimberidou Jamileh Noshari Thomas E. Anderson Peter R. C. Gascoyne 《Biomicrofluidics》2013,7(1)
Circulating tumor cells (CTCs) are prognostic markers for the recurrence of cancer and may carry molecular information relevant to cancer diagnosis. Dielectrophoresis (DEP) has been proposed as a molecular marker-independent approach for isolating CTCs from blood and has been shown to be broadly applicable to different types of cancers. However, existing batch-mode microfluidic DEP methods have been unable to process 10 ml clinical blood specimens rapidly enough. To achieve the required processing rates of 106 nucleated cells/min, we describe a continuous flow microfluidic processing chamber into which the peripheral blood mononuclear cell fraction of a clinical specimen is slowly injected, deionized by diffusion, and then subjected to a balance of DEP, sedimentation and hydrodynamic lift forces. These forces cause tumor cells to be transported close to the floor of the chamber, while blood cells are carried about three cell diameters above them. The tumor cells are isolated by skimming them from the bottom of the chamber while the blood cells flow to waste. The principles, design, and modeling of the continuous-flow system are presented. To illustrate operation of the technology, we demonstrate the isolation of circulating colon tumor cells from clinical specimens and verify the tumor origin of these cells by molecular analysis. 相似文献
749.
James Betts Clyde Williams Katherine Duffy Frances Gunner 《Journal of sports sciences》2013,31(13):1449-1460
Abstract Ingesting carbohydrate plus protein following prolonged exercise may restore exercise capacity more effectively than ingestion of carbohydrate alone. The objective of the present study was to determine whether this potential benefit is a consequence of the protein fraction per se or simply due to the additional energy it provides. Six active males participated in three trials, each involving a 90-min treadmill run at 70% maximal oxygen uptake (run 1) followed by a 4-h recovery. At 30-min intervals during recovery, participants ingested solutions containing: (1) 0.8 g carbohydrate · kg body mass (BM)?1 · h?1 plus 0.3 g · kg?1 · h?1 of whey protein isolate (CHO-PRO); (2) 0.8 g carbohydrate · kg BM?1 · h?1 (CHO); or (3) 1.1 g carbohydrate · kg BM?1 · h?1 (CHO-CHO). The latter two solutions matched the CHO-PRO solution for carbohydrate and for energy, respectively. Following recovery, participants ran to exhaustion at 70% maximal oxygen uptake (run 2). Exercise capacity during run 2 was greater following ingestion of CHO-PRO and CHO-CHO than following ingestion of CHO (P ≤ 0.05) with no significant difference between the CHO-PRO and CHO-CHO treatments. In conclusion, increasing the energy content of these recovery solutions extended run time to exhaustion, irrespective of whether the additional energy originated from sucrose or whey protein isolate. 相似文献
750.
Hui-Ting Goh Shailesh S. Kantak Katherine J. Sullivan 《Research quarterly for exercise and sport》2013,84(2):346-352
Reduced feedback during practice has been shown to be detrimental to movement accuracy in children but not in young adults. We hypothesized that the reduced accuracy is attributable to reduced movement parameter learning, but not pattern learning, in children. A rapid arm movement task that required the acquisition of a motor pattern scaled to specific spatial and temporal parameters was used to investigate the effects of feedback (FB) frequency (100% vs. 62% faded) on motor learning differences between 19 school-age children and 19 young adults. Adults and children practiced the task for 200 trials under the 100% or faded FB condition on Day 1 and returned on Day 2 for a no-FB retention test. On the retention test, children who practiced with reduced feedback performed with greater temporal parameter errors, but not pattern error, than children who received frequent feedback. Motor skill learning in children is influenced by feedback frequency during practice that affects parameter learning but not pattern learning. 相似文献