Governments as partners: The role of alliances in U.S. cleantech startup innovation

Accelerating innovation in clean energy technologies is a policy priority for governments around the world aiming to mitigate climate change and to provide affordable energy. Most research has focused on the role of governments financing R&D and steering market demand, but there is a more limited understanding of the role of direct government interactions with startups across all sectors. We propose and evaluate the value-creation mechanisms of network resources from different types of partners for startups, highlighting the unique resources of government partners for cleantech startups. We develop and analyze a novel dataset of 657 U.S. cleantech startups and 2,015 alliances with governments, firms, research organizations, and not-for-profit organizations from 2008 to 2012 and analyze short-term firm outcomes from the different alliances. Our findings highlight the importance of governmental partners in technology development alliances to catalyze cleantech startup innovation (the patenting activity of cleantech startups increases by 73.7 percent with every additional governmental technology alliance when compared to those startups that did not engage in such alliances) and as quality signals to private sector investors for licensing alliances (private financing deals increase by 155 percent for every additional license from a government organization). Overall, these findings extend the alliance perspectives on innovation, contribute to the emerging research on entrepreneurial ecosystems, and underline the need to develop empirical evidence in different sectors.     

Seasonal variations in markers of stress and oxidative stress in rats

High ambient temperature has been reported to increase oxidative stress by increasing lipid peroxidation and decreasing antioxidant defence in transition dairy cows. It is also known to cause an increase in plasma cortisol levels in goats, European hedgehog and human volunteers. High levels of glucocorticoids have been reported to decrease blood glutathione and erythrocyte superoxide dismutase activity in rats. Although institutional animal houses in research laboratories of developed countries maintain animals in air-conditioned rooms at constant temperature, the same is not true of animal houses in the developing countries especially those belonging to smaller institutions and this could affect the results of the experiments being conducted on these animals. The present research study was done to assess the effects of seasonal variations on the status of erythrocyte oxidative damage, antioxidant defence and plasma cortisol levels in adult female Wistar rats. Rats were kept in their home cages and were left in non-air-conditioned procedure rooms in two different seasons, Hot season (March-May) and Cool season (June to September). Erythrocyte Thiobarbituric acid reactive substances and plasma cortisol levels were significantly increased in rats exposed to high ambient temperature and humidity of the hot season as compared to the rats of the cool season. Erythrocyte reduced glutathione levels, erythrocyte glutathione peroxidase and superoxide dismutase activities were significantly decreased in the hot season group of rats. The results of our experiments showed that exposure of adult female Wistar rats to high ambient temperature and humidity of the hot season increases neuroendocrine stress, oxidative stress and decreases antioxidant defence in them.     

Doubly-terminated two-variable lossless ladder networks

In this paper necessary and sufficient conditions are derived for a two-variable positive real function to be the driving-point impedance of certain classes of doubly-terminated lossless ladder networks. Specifically, two classes of networks are studied: (a) the class of networks in which the lossless structure is a cascade of p₁- and p₂-variable two-ports, each two-port having its transmission zeros at the origin and/or at infinity; (b) the class of networks in which the lossless structure is a lowpass or highpass ladder network with series arms having p₁- and p₂-type elements in series and shunt arms having the p₁- and p₂-type elements in parallel. It is indicated that via suitable transformations of the variables, conditions for many other types of ladder structures can be derived.     

Cerebrospinal fluid free sialic acid and aspartate transaminase levels in meningitis

Background  Sialic acid (SA) is a nine carbon sugar derived from mannosamine and pyruvate. High levels of sialic acid and aspartate transaminase (AST) levels in cerebrospinal fluid have been described in pyogenic meningitis (PM) compared to tubercular meningitis (TBM). Objectives  To evaluate the levels of CSF free SA in PM and TBM and to assess the correlation between CSF free SA and CSF glucose or total protein levels. Patients and Methods  A total of 122 subjects were studied and divided into children and adults. Further, these have been subdivided into controls, PM and TBM. CSF free SA was estimated by thiobarbituric acid assay of Warren and AST by Reitmann and Frankel method. Results  CSF free SA and AST levels in children and adults were significantly high in PM (p<0.001) as compared to TBM and controls. Conclusion  A very high CSF free SA and AST were found to be characteristic of PM, making them useful parameters to differentiate PM from TBM.