高校党务信息管理系统的设计与实现

对党务信息管理系统进行需求分析,提出了系统开发的三层体系结构,并对该系统的功能模块进行详细设计.高校党务工作要引进先进的信息化科学技术和现代化管理方法,开发党务信息管理系统至关重要.     

A multiple-dose pharmacokinetics of polyethylene glycol recombinant human interleukin-6 (PEG-rhIL-6) in rats

Radiation therapy has been widely applied in cancer treatment. However, it often causes thrombocytopenia (deficiency of white blood cells) as an adverse effect. Recombinant human interleukin-6 (rhIL-6) has been found to be a very effective way against this thrombocytopenia, but IL-6 has low stability in blood, which reduces its efficacy. To increases the stability and half-life of rhIL-6, it was modified by polyethylene glycol (PEG). The pharmacokinetics and the tissue distribution of PEG-rhIL-6 labeled with ¹²⁵I were examined after subcutaneous injection in rats. The pharmacokinetic pattern of PEG-rhIL-6 was defined with linear-kinetics, and we fitted a one-compartment model with half-lives of 10.44–11.37 h (absorption, t _{1/2K a}) and 19.77–21.53 h (elimination, t _1/2Ke), and peak concentrations at 20.51–21.96 h (t _peak) in rats. Half-lives and t _peak of PEG-rhIL-6 were longer than those of rhIL-6 previously reported. In the present study, for deposition of PEG-rhIL-6 in rats, the tissue distribution examination showed that blood was the major organ involved, rather than liver. However, as to the elimination of PEG-rhIL-6, the major organ was the kidney. The excretion fraction of the injection dose recovered from urine was 23.32% at 192 h after subcutaneous administration. Less than 6% of PEG-rhIL-6 was eliminated via the feces at 192 h. These results indicate that PEG-rhIL-6 is a good candidate drug formulation for patients with cancer.     

Lumped parameter model for resonant frequency estimation of a thermoacoustic engine with gas-liquid coupling oscillation

Gas-liquid coupling oscillation is a novel approach to reducing the resonant frequency and to elevating the pressure amplitude of a thermoacoustic engine. If a thermoacoustic engine is used to drive low-frequency pulse tube refrigerators, the frequency matching between the thermoacoustic engine and the refrigerator plays an important role. Based on an acoustic-electric analogy, a lumped parameter model is proposed to estimate the resonant frequency of a standing-wave thermoacoustic engine with gas-liquid coupling oscillation. Furthermore, a simplified lumped parameter model is also developed to reduce the computation complexity. The resonant frequency dependence on the mean pressure, the gas space volume, and the water column length is computed and analyzed. The impact of different working gases on the resonant frequency is also discussed. The effectiveness of the models is validated by comparing the computed results with the experimental data of the gas-liquid coupling oscillation system. An increase in the mean working pressure can lead to a rise in the resonant frequency, and a lower resonant frequency can be achieved by elongating the liquid column. In comparison with nitrogen and argon, carbon dioxide can realize a lower frequency due to a smaller specific heat ratio.     

A new principle and device for large aircraft components gaining accurate support by ball joint

How to obtain an accurate support for large components by ball joint is a key process in aircraft digital assembly. A novel principle and device is developed to solve the problem. Firstly, the working principle of the device is introduced. When three or four displacement sensors installed in the localizer are touched by the ball-head, the spatial relation is calculated between the large aircraft component’s ball-head and the localizer’s ball-socket. The localizer is driven to achieve a new position by compensation. Relatively, a support revising algorithm is proposed. The localizer’s ball-socket approaches the ball-head based on the displacement sensors. According to the points selected from its spherical surface, the coordinates of ball-head spherical center are computed by geometry. Finally, as a typical application, the device is used to conduct a test-fuselage’s ball-head into a localizer’s ball-socket. Positional deviations of the spherical centers between the ball-head and the ball-socket in the x, y, and z directions are all controlled within ±0.05 mm under various working conditions. The results of the experiments show that the device has the characteristics of high precision, excellent stability, strong operability, and great potential to be applied widely in the modern aircraft industry.     

民间风俗与谐音现象

民间风俗是中国传统文化的一种显现,这种文化与语言的应用有密切的关系,其中谐音就是一种智慧的民族语言应用形式。文章旨在探讨民间风俗中谐音的种类,以及产生谐音语言的原因。     

新型三向管路动力吸振器设计方法研究

文章针对管路的低频线谱和三向振动传递的特点,设计了一种新型悬臂梁式动力吸振器结构。基于梁的波动理论和结构阻抗分析法,推导了吸振器插入损失计算公式。通过参数分析获得了吸振器质量、弹簧片尺寸与其减振效果之间的定量关系。试验结果表明,该文提出的吸振器设计方法和吸振器结构能够达到预期的减振效果。     

“总体国家安全观”视域下普通高校国防教育模式的创新路径

普通高校开展国防教育已有近30年的历史。近30年来,国防教育在高校人才培养方面虽取得了显著成绩,但新形势下仍面临着严峻的生存与发展困境。唯有坚持以"总体国家安全观"为指导,重新定位高等院校国防教育的目标和发展导向,增设"非传统安全"和"内部安全"的教学内容,开展研究性教学模式,实施"军事院校与地方高校相配合、技能训练与思想浸润相结合、传统科目与特色项目相融合"的军训模式,高校国防教育方能走出困境、破解难题,迎来崭新的明天。     

30年来我国高校国防教育的发展历程、历史经验与未来前瞻

自1985年开展学生军训试点以来,我国高校国防教育已走过30年的历程.经过初步探索期、全面发展期两个阶段,高校国防教育工作取得了一定成绩,积累了宝贵的经验.对其发展历程、主要成就、历史经验、当前困境等问题进行总结与分析,有助于进一步推进高校国防教育工作的科学发展.     

基于绿色旅游视角下的河南省旅游业转型升级研究

通过研究绿色旅游的概念,分析河南省绿色旅游的发展现状,提出河南省发展绿色旅游的对策,从而为河南省实施旅游业转型升级,实现美丽河南提供智力支持.     

品质农业：湖州现代农业发展的着力点

品质农业是湖州市现代农业发展的方向,是现阶段湖州农业发展的目标定位。本文对品质农业发展的背景及理论基础进行梳理提炼,在此基础上分析湖州市发展品质农业的优势及有利条件,并对湖州市品质农业的概念及特征进行定义,最后列举了湖州品质农业发展的典型实践。