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31.
Zhuoqi Li Weiran Liu Tian Qiu Lan Xie Weixing Chen Ran Liu Ying Lu Keith Mitchelson Jundong Wang Jie Qiao Jing Cheng 《Biomicrofluidics》2014,8(2)
Thermotaxis has been demonstrated to be an important criterion for sperm evaluation, yet clinical assessment of thermotaxis capacity is currently lacking. In this article, the on-chip thermotaxis evaluation of human sperm is presented for the first time using an interfacial valve-facilitated microfluidic device. The temperature gradient was established and accurately controlled by an external temperature gradient control system. The temperature gradient responsive sperm population was enriched into one of the branch channels with higher temperature setting and the non-responsive ones were evenly distributed into the two branch channels. We employed air-liquid interfacial valves to ensure stable isolation of the two branches, facilitating convenient manipulation of the entrapped sperm. With this device, thermotactic responses were observed in 5.7%-10.6% of the motile sperm moving through four temperature ranges (34.0-35.3 °C, 35.0-36.3 °C, 36.0-37.3 °C, and 37.0-38.3 °C, respectively). In conclusion, we have developed a new method for high throughput clinical evaluation of sperm thermotaxis and this method may allow other researchers to derive better IVF procedure. 相似文献
32.
Keith J. Topping 《Learning and Instruction》2010,20(4):339-343
Peer assessment is very various in its implementation. Six studies of peer assessment are reviewed, four of them in higher education. A literature review is followed by five empirical studies. Strengths and weaknesses of each study are considered and issues are raised. Variables in peer assessment needing further exploration are extricated – in sample definition, specification of type of peer assessment, organisational nature of the intervention, and the measures which are used to evaluate change. It is suggested that further experimental and quasi-experimental studies are necessary to contrast one or two of these variables at a time. 相似文献
33.
The importance of effector visual feedback has previously been indicated using an opaque screen to prevent sight of the catching hand for the final 150–200 ms of a flight path of 850 ms in total. Attention was drawn to the finding that the ability to position the arm correctly in the line of flight of the ball deteriorated as a consequence of the number of trials without visual feedback. However, the use of only 20 test trials allows a possibility that the proprioceptive system may be able to re‐establish predominant control under conditions of prolonged visual decrement. In order to verify this notion, the number of experimental trials was quadrupled for 24 subjects of mixed sex in a replication of the initial paradigm. The results provided preliminary support for the view that the positioning of the catching arm is more seriously affected by visual occlusion than the timing of the grasp phase. However, increments in accuracy of limb orientation were evidenced in all screen conditions, as the number of trials increased. The grasp component of one‐handed catching appeared to remain unaffected by the increase in experimental trials. The relative influence of skill level on catching errors was next addressed by comparing the performance of the six best and worst catchers in the group. The results did not support previous research which found a relation between skill level and error type. The number of position, but not grasp, errors decreased as a function of task practice for both subgroups. Future investigations should, perhaps, focus on the developmental nature of movement control in one‐handed catching to obtain a clearer picture of this relation. 相似文献
34.
顺应全球化:发展中国家高等教育的变迁与改革 总被引:8,自引:0,他引:8
随着全球化经济就业模式的变化及对技能的需求 ,高等教育的内涵出现了变化。旨在满足国家优先发展战略的自上而下的高等教育投资政策已难以满足大众的迫切需求 ,基于个人和社会需求的自下而上的决策观更能满足人才、职业全球流动性日益增加的社会现实。根植于学术研究的知识生产模式难以在新形势下发挥作用 ,而与自下而上的政策建构相适应的知识生产模式 ,将有利于发展中国家在国际高等教育市场中保持竞争力 相似文献
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36.
Elissa Burton Kaela Farrier Keith D. Hill Jim Codde Phil Airey Anne-Marie Hill 《Journal of sports sciences》2018,36(6):666-678
The objective of this systematic review and meta-analysis was to evaluate the effectiveness of peers to deliver programs or encourage older people to be physically active and improve physical outcomes. Peer reviewed articles published in English between January 1976 and June 2016, retrieved from six databases according to the predefined inclusion criteria were included. Where possible results were pooled and meta-analyses conducted. Eighteen articles were included in the review, a total of 3,492 intervention participants, average age 66.5 years and 67.1% were female. Overall, study quality was medium to high. Interventions mainly included resistance, flexibility and cardiovascular training, however there was one aquatic exercise group. Eight studies were delivered by peers and five utilised peer support, which included advice and being positive but was not directly linked to an exercise intervention. While 16 of the 18 studies reported improvement in levels of physical activity and/or noted physical benefits by peer involvement, the meta-analyses findings supported the control groups for the six-minute-walk-test and the timed-up-and-go test. Findings from this review suggest exercise programs involving peers can promote and maintain adherence to exercise programs. However, results were inconclusive as to whether peers have a positive effect on improving older people’s physical function. 相似文献
37.
Intellectual Disability and Developmental Risk: Promoting Intervention to Improve Child and Family Well‐Being 下载免费PDF全文
Keith A. Crnic Cameron L. Neece Laura Lee McIntyre Jan Blacher Bruce L. Baker 《Child development》2017,88(2):436-445
Initial intervention processes for children with intellectual disabilities (IDs) largely focused on direct efforts to impact core cognitive and academic deficits associated with the diagnosis. Recent research on risk processes in families of children with ID, however, has influenced new developmental system approaches to early intervention. Recent risk and resilience processes are reviewed that connect stress, family process, and the high rates of behavioral problems in children with ID that have substantial influence on child and family outcomes. These models are linked to emerging evidence‐based intervention processes that focus on strategic parent skill training and mindfulness interventions that reduce parental stress and create indirect benefits for children's behavioral competencies. A family‐focused developmental systems approach (M. J. Guralnick, 2011) is emphasized. 相似文献
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39.
Educational Studies in Mathematics - In mathematics education research, proofs are often conceptualized as sequences of mathematical assertions. We argue that this ignores proofs that contain... 相似文献
40.