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In this paper, factors affecting achievement in the University of Cambridge GCE A‐level geography examination, for a sample of 470 students, are analysed in terms of 17 variables grouped into the four factors of family background, cognitive ability, study orientation and school influence. Path analysis established a composite factor of study orientation to have the major causal association with achievement; this effect was direct, and there were no significant indirect effects from the family background or cognitive factors. Family background was generally not found to be associated with achievement, but an important association between ‘disembedding’ spatial ability and practical geography was suggested. A teacher's profile and amount of fieldwork undertaken were also found to correlate significantly with achievement. The main association with attainment was, however, achievement at O‐level, both in terms of O‐level achievement generally and in geography specifically. Five predictor variables were presented which accounted for a greater percentage of variation than has previously been explained. The consequences of the research for teachers and students are briefly addressed in a number of concluding remarks.  相似文献   
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This article presents a review of research studies examining instructional methods reported in the social work education literature published between 1998 and 2008. From a sample of 91 studies, 31 were identified as having used either a single group pre/post test design or a comparison of two or more groups and inclusion of a learning outcome measure. Most of the studies were deficient in either the employment of comparison groups, pre/post designs, utilization of multiple learning outcome measures, or a clear delineation of the connection between teaching methods and learning outcomes. Very few studies were based on previous work. A challenge is made to the field to conduct better designed studies and several suggestions for doing so are offered.  相似文献   
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Hiring employees with advanced education, training, and experience has been a prevalent human resource practice in dynamic science-based industries, and a growing body of literature has demonstrated the importance of scientists in such fields. Little research has attempted to distinguish the functional from the symbolic roles of scientists, however. We develop an integrative theoretical framework to separate the productive and legitimating effects of scientists on strategic alliance formation of firms. Results from a longitudinal analysis of more than 300 U.S. biotechnology firms between 1988 and 1999 suggest a positive relationship between ratio of scientists and R&D alliance partners as well as a positive relationship with finance alliance partners. Scientists influence partner attraction more strongly for firms that are less-well-connected, and they become less prominent in fostering finance ties as the industry practice of partnership becomes more institutionalized. We conclude that scientists serve more than just a research function in knowledge-intensive industries. Implications for building interorganizational networks and managing human resources in such industries are discussed.  相似文献   
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The exceptional performance of Dell Computer in recent years illustrates an innovative response to a fundamental competitive factor in the personal computer industry - the value of time. This article shows how Dell's strategies of direct sales and build-to-order production have proven successful in minimizing inventory and bringing new products to market quickly, enabling it to increase market share and achieve high returns on investment. The Dell case illustrates how one business model may have inherent advantages under particular market conditions, but it also shows the importance of execution in exploiting those advantages. In particular, Dell's use of information technology (IT) has been vital to executing both elements of its business model - direct sales and build-to-order - and provides valuable insights into how IT can be applied to achieve speed and flexibility in an industry in which time is critical. Many of the insights gained from this case can be applied more generally to other time-dependent industries, suggesting that the findings from the Dell case will have implications for a growing number of companies and industries in the future.  相似文献   
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Liposomes, especially cationic liposomes, are the most common and well-investigated nanocarriers for biomedical applications, such as drug and gene delivery. Like other types of nanomaterials, once liposomes are incubated in a biological milieu, their surface can be immediately cloaked by biological components to form a protein corona, which confers a new ‘biological identity’ and modulates downstream interactions with cells. However, it remains unclear how the protein corona affects the transportation mechanism after liposomes interact with cells. Here, we employed home-made aggregation-induced-emission-visualized nanoliposomes TR4@Lipo as a model to investigate transportation with or without the protein corona by optical imaging techniques. The results show that the protein corona can change the cellular transportation mechanism of TR4@Lipo from energy-independent membrane fusion to energy-dependent endocytosis. The protein corona also modulates the intracellular distribution of loaded cargoes. This knowledge furthers our understanding of bio-nano interactions and is important for the efficient use of cationic liposomes.  相似文献   
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