体力活动与癌症生存研究的10大问题

摘要：今天的美国有1 400万的癌症存活者,其中的很多存活者中都接受了多种治疗,包括手术、放疗、化疗、靶向治疗等。这些治疗能够延长生存时间,但同时也会带来很多急慢性的副作用,危害健康,影响生活质量。体力活动（PA）与癌症生存这一领域发展迅速,主要研究PA对癌症患者的影响。基于该领域的研究进展,提出了以下10大研究问题：1）PA能够降低癌症复发风险、和/或提高存活吗？2）PA能够影响癌症治疗决策、完成率、和/或患者对治疗的反应吗？3）癌症存活者的最佳运动处方是什么？4）静坐少动行为对癌症存活者有何影响？5）癌症存活者最有效的体力活动干预方案是什么？6）哪些癌症会影响病人对PA的反应？7）癌症存活者进行体力活动时需要注意的安全问题有哪些？8）哪些具体的癌症症状可以由PA解决？9）对于癌症晚期患者,体力活动还有何作用？10）如何将体力活动研究结果转化到临床和社区肿瘤实践中来？上述问题的回答至关重要,这不仅关系到体力活动和癌症存活这一研究领域的发展,更重要的是,能够为每年数百万新诊断为癌症的病人、正在接受癌症治疗的病人、治疗结束处于恢复中的病人或是那些正在与晚期癌症抗争的病人带来福音。     

Closing the gap: supporting literacy through a computer-assisted-reading-intervention

Schools in England are expected to ‘close the gap’ for a range of vulnerable pupils who are achieving below the levels seen amongst their same-aged peers. They are also highly accountable for additional funding that is provided to support this goal. The project reported here involved collating and analysing a range of data in order to evaluate the impact of a widely used computer-assisted-reading-intervention (CARI). Sixteen primary school pupils, all of whom were identified by their school as underachieving in literacy, used the CARI daily over a five-week period. The post-intervention data showed some clear gains in reading and spelling skills for all bar one of the children. The findings are discussed in relation to the wider literatures on CARIs. The research concludes that the CARI under investigation offers a useful and cost-effective adjunct to whole-class and group reading instruction and may be particularly beneficial for supporting the learning of pupils who are struggling to consolidate the knowledge and skills covered in their regular classroom reading instruction.     

Maximizing recovery time between knock-out races improves sprint cross-country skiing performance

Background:In a sprint cross-country(XC)ski competition,the difference in recovery times separating the first and the second semi-final(SF)heats from the final(F)may affect performance.The aim of the current study was to compare the effects of longer vs.shorter recovery periods prescribed between the 3 knock-out races of a simulated sprint XC ski competition involving a prologue(P),quarter-final(QF),SF,and F.Methods:Eleven well-trained XC ski athletes completed 2 simulated sprint XC ski competitions on a treadmill involving 4×883-m roller-ski bouts at a 4°incline using the gear 3 ski-skating sub-technique.The first 3 bouts were completed at a fixed speed(PFIX,QFFIX,and SFFIX)corresponding to~96%of each individual’s previously determined maximal effort.The final bout was performed as a self-paced sprint time trial(FSTT).Test conditions differed by the time durations prescribed between the QFFIX,SFFIX,and FSTT,which simulated real-world XC ski competition conditions using maximum(MAX-REC)or minimum(MIN-REC)recovery periods.Results:The FSTT was completed 5.4±5.5 s faster(p=0.009)during MAX-REC(179.2±18.1 s)compared to MIN-REC(184.6±20.0 s),and this was linked to a significantly higher power output(p=0.010)and total metabolic rate(p=0.009).The pre FSTT blood lactate(BLa)concentration was significantly lower during MAX-REC compared to MIN-REC(2.5±0.8 mmol/L vs.3.6±1.6 mmol/L,respectively;p=0.027),and the pre-to-post FSTT increase in BLa was greater(8.8±2.1 mmol/L vs.7.1±2.3 mmol/L,respectively;p=0.024).No other differences for MAX-REC vs.MIN-REC reached significance(p>0.05).Conclusion:Performance in a group of well-trained XC skiers is negatively affected when recovery times between sprint heats are minimized which,in competition conditions,would occur when selecting the last QF heat.This result is combined with a higher pre-race BLa concentration and a reduced rise in BLa concentration under shorter recovery conditions.These findings may help inform decision making when XC skiers are faced with selecting a QF heat within a sprint competition.     

Outcomes for Women and Infants Following Assisted Conception: Implications for Perinatal Education,Care, and Support

Assisted conception is becoming an increasingly more common treatment option for women and couples who experience fertility problems. Links have been made in the literature between assisted conception and a greater incidence of pregnancy or birth complications, low birth weight or premature babies, and babies with congenital abnormalities. In addition, evidence suggests that the experience of assisted conception may influence the development of early mothering relationships and impact parenting adjustment. Although this commentary article does not strategically review all available literature, it provides an overview of the health issues that women and families undergoing assisted conception have experienced or may experience. Through raising awareness and promoting discussion of these issues, practitioners will be better equipped to provide informed education and support.     

Question‐posing and question‐responding: the heart of ‘Possibility Thinking’ in the early years

Drawing on research that sought to explore the characteristics of ‘Possibility Thinking’ as central to creativity in young children's learning, this paper considers question‐posing and question‐responding as the driving features of ‘Possibility Thinking’ (PT). This qualitative study employed micro‐event analysis of peer and pupil–teacher interaction. Events were sampled from two early years settings in England, one a Reception classroom (4‐ to 5‐year olds) and the other a Year 2 classroom (6‐ to 7‐year olds). This article arises out of the second stage of an ongoing research programme (2004–2007) involving the children and practitioners in these settings. This phase considers the dimensions of question‐posing and the categories of question‐responding and their interrelationship within PT. Three dimensions of questioning were identified as characteristic of PT. These included: (i) question framing, reflecting the purpose inherent within questions for adults and children (including leading, service and follow‐through questions); (ii) question degree: manifestation of the degree of possibility inherent in children's questions (including possibility narrow, possibility moderate, possibility broad); (iii) question modality, manifestation of the modality inherent in children's questions (including verbal and non‐verbal forms). The fine‐grained data analysis offers insight into how children engage in PT to meet specific needs in responding to creative tasks and activities and reveals the crucial role that question‐posing and question‐responding play in creative learning. It also provides more detail about the nature of young children's thinking, made visible through question‐posing and responding in engaging playful contexts.     

e is for exploration: Assessing hard-to-measure learning outcomes

The focus of this paper is on the use of e‐technologies to enable higher education to better assess aspects of learning that have proved difficult to assess using more conventional means. Higher education describes the knowledge and abilities it intends its graduates to have acquired before graduation, and it has a wide range of approaches to assess these. Higher education also seeks affective outcomes in the form of values, attitudes, behaviours and related attributes or dispositions, and these have consistently proved more difficult to assess by examination or assignment. After graduation, however, graduates are often assessed within the professions via portfolios, interview and peer or expert review. Assessment may focus on teamwork and networking skills, productivity, creativity and values fit to the profession. How can e‐technologies help with these forms of assessment? This paper reviews some of the e‐based approaches and explorations that have supported or could support assessment of affective attributes. At each stage, the paper seeks to establish the common elements of assessment in the different regimes and how e‐assessment contributes, or may contribute in the future. The paper concludes that many of the strengths of e‐assessment lend themselves to an evaluation paradigm rather than to conventional assessment for intended learning outcomes.