排序方式: 共有67条查询结果,搜索用时 400 毫秒
31.
Bharosay A Saxena K Varma M Bharosay VV Pandey A 《Indian journal of clinical biochemistry : IJCB》2011,26(3):279-282
Stroke being the third leading cause of death and foremost cause of disability, if potential diagnostic utility of blood borne
protein biomarkers in predicting acute stroke is established, it would be a substantial adjunct to computerized tomography
and magnetic resonance imaging which have their own limitations. This study was done to correlate serum Interleukin 6, high
sensitivity C reactive protein at the time of admission with neurological worsening assessed by NIHSS at the time of admission
and 7 days after admission. 46 Patients admitted in neurology department SAIMS, Indore with first ever ischemic stroke within
72 h of onset were included in the study. All patients with history of stroke of more than 72 h onset, Infection & peripartum
stroke were excluded from the study. Disability scoring was done by NIHSS and their serum samples assayed for hsCRP, IL6 by
commercially available quantitative sandwich enzyme-linked immunoadsorbent assay kits. Serum samples of 50 control cases which
included healthy volunteers and staff from SAIMS were also analyzed for hsCRP, IL6 for comparative study. A significant correlation
was observed between NIHSS scoring and serum hsCRP and IL6 at the time of admission. Patients with initial high serum IL6
and hsCRP also showed significant clinical deterioration as assessed by NIHSS scoring 7 days after admission. Elevated hsCRP
and IL6 within 72 h of admission strongly correlated with functional disability in study population in India and may serve
as useful adjunct to CT Scan in emergency setting. 相似文献
32.
33.
Kiran Saxena N. B. Vasavada Ravi Saxena 《Indian journal of clinical biochemistry : IJCB》1991,6(2):135-141
The glycosylated haemoglobin was measured in two different categories of diabetic subjects. In poorly controlled subjects
of group II, a significant alteration in serum proteins was observed. Total protein along with albumin concentrations were
decreased and α2 globulin fraction was increased. Insulin therapy resulted in normalisation of blood glucose and gradual decrease in glycosylated
haemoglobin in the therapy period of eight weeks. This also resulted in a rise of total protein and albumin concentrations
with a decrease in α2 fraction. The present study indicates that prolonged therapy of insulin is needed to correct the serum protein abnormalities
in diabetics. 相似文献
34.
35.
36.
Harbans Lal Nirmal Gulati Saroj Nidhi Sandooja Kiran Chugh 《Indian journal of clinical biochemistry : IJCB》1995,10(2):103-105
Plasma and erythrocyte magnesium levels were estimated in preeclampsia and eclampsia. Mean plasma as well as erythrocyte magnesium
concentrations were found to be significantly lowered than the controls. Hypomagnesemia was directly related with the severity
of the disease. Plasma calcium concentration however, was not significantly altered. 相似文献
37.
Fasting blood sample of 50 normal subjects (control) and 100 patients of breast cancer were investigated for serum total cholesterol,
high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein, high density lipoprotein
cholesterol:low density lipoprotein cholesterol ratio and total cholesterol:high density lipoprotein cholesterol ratio during
breast cancer of women. Five cancer stages, types, age groups, parity and menopausal status were undertaken for the study.
It was observed that there was a significant rise in serum total cholesterol and low density lipoprotein cholesterol whereas
high density lipoprotein cholesterol and very low density lipoprotein cholesterol were not significant. The ratio of high
density lipoprotein cholesterol:low density lipoprotein cholesterol and total cholesterol:high density lipoprotein cholesterol
values increased significantly in breast cancer patients. 相似文献
38.
Goverdhan Lal S. P. S. Yadav S. K. Aggarwal Sadhna Bansal Kiran Chugh Harbans Lal 《Indian journal of clinical biochemistry : IJCB》1996,11(1):46-48
Plasma vitamin E and malondialdehyde (MDA) concentrations were estimated in a group of 25 patients (17 males and 8 females) with head and neck cancer and the results were compared with a group of normal healthy controls. Plasma vitamin E levels were found to be significantly reduced while MDA levels were increased in patients than the controls. The fall in vitamin E was nearly same in all the patients studied irrespective of the site, TNM stage, histopathology and character of lesion. The levels did not vary immediately after radiotherapy but were significantly increased 3 months after the radiotherapy. These preliminary data suggest that the cancer patients have suboptimal vitamin E status which may be a contributory factor for increased lipid peroxidation in such cases. 相似文献
39.
40.
Swati Rajput Deepanshu Paliwal Manisha Naithani Aashish Kothari Kiran Meena Satyavati Rana 《Indian journal of clinical biochemistry : IJCB》2021,36(3):266
Currently, world is facing a global outbreak causing a pandemic threat known as COVID-19. This infectious disease is triggered by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Gut microbiota harbours multi species community with a strong impact on host immune homeostasis. However, our knowledge about this gut microbiota and its symbiotic relationship with immune activation in association with SARS-CoV-2 is limited. Unbalanced bacterial flora with too many opportunistic infections can shift immune system towards a cascade of inflammatory responses leading to multi organ damage. This review will highlight immune-regulation via various mechanisms in SARS-CoV-2 infection. Diet has an unbelievable influence on gut microbiome that allows a new state of homeostasis to be reached through timing, frequency and duration of intake. This review article focuses on gut, lung microbiota and immunomodulation with specific attention on immune activation by gut microbiota. 相似文献