Convergent genomic signatures of high-altitude adaptation among domestic mammals

Abundant and diverse domestic mammals living on the Tibetan Plateau provide useful materials for investigating adaptive evolution and genetic convergence. Here, we used 327 genomes from horses, sheep, goats, cattle, pigs and dogs living at both high and low altitudes, including 73 genomes generated for this study, to disentangle the genetic mechanisms underlying local adaptation of domestic mammals. Although molecular convergence is comparatively rare at the DNA sequence level, we found convergent signature of positive selection at the gene level, particularly the EPAS1 gene in these Tibetan domestic mammals. We also reported a potential function in response to hypoxia for the gene C10orf67, which underwent positive selection in three of the domestic mammals. Our data provide an insight into adaptive evolution of high-altitude domestic mammals, and should facilitate the search for additional novel genes involved in the hypoxia response pathway.     

文化立校:现代学校文化建设探究

文化是学校的灵魂,是学校特色的重要体现.加强学校文化建设是学校发展的需要,建设的需要,管理的需要,名校创建的需要.新的历史时期,要充分认识文化建设对学校长远发展的重要意义,把学校文化建设当成一项全局性工程抓实抓好.文化立校,举足轻重,意义深远,是打造学校核心竞争力的必由之路.     

Investigating Elementary and Middle School Students’ Subjective Well-Being and Mathematical Performance in Shanghai

Students in Shanghai ranked at the top in mathematics on the past two assessments of the Program for International Student Assessment (PISA). However, even though Asian students in general, and Chinese students in particular, ranked at the top in mathematics, we know little about Shanghai students’ subjective well-being (SWB). This paper reports two studies that investigated the SWB of elementary and middle school students in Shanghai, as well as their mathematics performance. It is found that the mean scores of elementary school students on all scales of SWB are significantly higher than those of middle school students, representing a large drop for students when moving from elementary to middle school. Furthermore, students’ mathematics performance is moderately correlated with their SWB. And for Grade 6, students’ SWB affects their mathematics performance, especially from academic self-concept, attentiveness in the classroom, and relationship with teachers.     

学科信息门户:概念、结构与关键技术

以信息与应用高度集成、个性化和智能化为显著特征的新一代学科信息门户系统框架正在成为构建基于WWW的专业数字图书馆的理想模式。网络信息技术如门户构件、跨系统集成检索、元搜索引擎和智能代理等技术的迅速发展,为构建学科信息门户提供了关键技术支撑。图4。参考文献9。     

对图书馆OPAC分类数据的分析

本文指出了OPAC分类数据中存在的问题，并对存在问题的原因进行了剖析，提出了改进建议。     

浅析基于点击呼叫的网络营销

点击呼叫是电子商务时代最流行的新型语音通讯工具,必将成为未来网络营销发展的新趋势。首先介绍点击呼叫的概念和特点,然后详细分析在网络营销活动中实施点击呼叫服务的必要性、可行性,并论述点击呼叫对网络营销的影响,最后探讨性地提出基于点击呼叫的网络营销模式以及实现条件。     

国内部分高校卫星电视接收系统建设现状分析--以网络资源调研为主体的分析

依据网络搜索的35所拥有卫星电视接收系统的高等院校网站内容作为研究对象，从网站提供的数据、设备、节目内容、节目利用方式等方面的现状进行分析研究，旨在为国内高校的卫星电视接收系统的建设提供发展思路。     

英语国家初等学校的课外活动

英语国家小学课外活动内容丰富,形式多样。课外活动与课堂教学相联系,课外活动既符合学生的兴趣,又重视培养学生的意志品质及团队精神。在课外活动的运作方面,也是以学校为主但又依靠家长与社会并引入社会教育机构的力量,从而使学校的课外活动充满活力。     

用单片机I/O引脚实现A/D功能的原理与应用

本文利用现行有些单片机输入，输出(I／O)引脚的输入阻抗高、输出驱动能力强的特性，分析了用I／O引脚实现模数转移的原理，并在此基础上，提出了这种方法在电阻测量、键盘检测中的应用。通过该方法的讨论可开阔解决问题的思路。     

图书情报事业在可持续发展战略中的地位与作用

本文从可持续性发展战略系统的因素构成、系统构成、图书情报子系统的功能及自身建设等方面论述了图书情报事业在可持续发展战略中的地位与作用，使人们认识到图书情报事业是可持续发展战略系统中的重要组成因素之一，以及作为可持续发展战略系统中的一个子系统的系统功能与作用。