Examining Change in Cortisol Patterns During the 10‐Week Transition to a New Child‐Care Setting

The transition to out‐of‐home child care brings a number of challenges for children, including complex peer interactions and extended separations from parents. Children often show a midmorning to afternoon rise in cortisol on child‐care days, compared to the typical diurnal decline seen at home. Changes in cortisol were examined in a wide age range of children (N = 168; 1.2 months to 8 years, M = 3.27 years) during the 10‐week transition to a new child‐care setting. Structural equation modeling using latent change scores showed that children experienced an increase in the cortisol rise at child care across the 10‐week transition. Furthermore, child age moderated the difference between home‐ and child‐care cortisol patterns. Findings are placed in a developmental context, and potential implications and future directions are discussed.     

Effects of an Attachment‐Based Intervention on Child Protective Services–Referred Mothers' Event‐Related Potentials to Children's Emotions

This study examined the neurobiology of maternal sensitivity to children's emotions among mothers involved with Child Protective Services (CPS) and low‐risk comparison mothers (M_age = 31.6 years). CPS‐referred mothers participated in the Attachment and Biobehavioral Catch‐up (ABC) intervention or a control intervention. Mothers' event‐related potentials (ERPs) were measured while they categorized images of children with crying, laughing, and neutral expressions. CPS‐referred ABC mothers (n = 19) and low‐risk comparison mothers (n = 30) showed a larger enhancement of ERP responses for emotional faces relative to neutral faces than CPS‐referred control mothers (n = 21). Additionally, the magnitude of ERP responses to emotional faces was associated with observed maternal sensitivity. Findings add to the understanding of the neurobiology of deficits in parenting and suggest that these deficits are changeable through a parenting intervention.     

Rapid microfluidic solid-phase extraction system for hyper-methylated DNA enrichment and epigenetic analysis

Genetic sequence and hyper-methylation profile information from the promoter regions of tumor suppressor genes are important for cancer disease investigation. Since hyper-methylated DNA (hm-DNA) is typically present in ultra-low concentrations in biological samples, such as stool, urine, and saliva, sample enrichment and amplification is typically required before detection. We present a rapid microfluidic solid phase extraction (μSPE) system for the capture and elution of low concentrations of hm-DNA (≤1 ng ml⁻¹), based on a protein-DNA capture surface, into small volumes using a passive microfluidic lab-on-a-chip platform. All assay steps have been qualitatively characterized using a real-time surface plasmon resonance (SPR) biosensor, and quantitatively characterized using fluorescence spectroscopy. The hm-DNA capture/elution process requires less than 5 min with an efficiency of 71% using a 25 μl elution volume and 92% efficiency using a 100 μl elution volume.     

The relationship between motor skill proficiency and body mass index in preschool children

The purpose of this study was to examine the relationship between motor proficiency and body mass index (B/MI) in preschool children. Thirty-eight children ages 4-6 years had their BMI calculated and were assessed using the Movement Assessment Battery for Children-2 (MABC-2; Henderson, Sugden, & Barnett, 2007). These data were analyzed in two ways. The correlation between BMI and MABC-2 percentile ranks was calculated. Next, the groups were subdivided based on BMI status (high, M = 85.5; medium, M = 49.8; low, M = 10.8), and compared using t tests to determine if differences existed in MABC-2 percentile ranks. No significant relationship existed between MABC-2 and BMI percentile ranks (r = -.237). However significant differences in MABC-2 percentile ranks existed between high and low (p = .042), and high and medium (p = .043) groups. These results suggest that preschool children classified as overweight or obese may have lower motor proficiency than their normal weight and under weight peers. This study indicates there is a direct relationship between motor proficiency and BMI in the preschool population.     

ACADEMY RESEARCH INSTITUTES AND UNIVERSITIES

Up until now, CEPES, the UNESCO European Centre for Higher Education, was more concerned about universities than about the academies of sciences in the countries making up the region it serves, even though both types of institutions do research. Although university teaching was traditionally linked to research as in the Humboldtian model of the university, the two functions became increasingly separate in eastern Europe. Now, as eastern and central Europe undergo transition to democracy and market economies, it is perhaps time to consider a redefinition and possibly a fusion of roles with academies and universities co‐operating closely for excellence in teaching and in research.     

Self Organising Wayfinding Support for Lifelong Learners

Lifelong learning puts learner self-direction centre-stage. However, increased responsibility should not come at the price of over-burdening or abandonment of learners as they progress along their learning journey. This paper introduces an approach to wayfinding support for lifelong learners based on self-organisation theory. It describes an architecture which supports the recording, processing and presentation of collective learner behaviour designed to create a feedback loop informing learners of successful paths towards the attainment of learning goals. The approach is presented as an alternative to methods of achieving adaptation in hypermedia-based learning environments which involve learner modelling. The article concludes with a discussion of the questions being addressed in our ongoing research.     

Student Success in University Education: A Multi-measurement Study of the Impact of Student and Faculty Factors on Study Progress

This study focuses on the factors that determine study progress and numerical success rate in higher education. Study progress is influenced at three levels, namely the student level, course/institute level and government level. It is expected that various groups of economic, social, psychological and organisational factors will together influence the study progress. This study uses a multi-level and multi-disciplinary framework, in so far as it considers all of these factors at the different levels. The database contains about 9,000 students and 60 courses at the institutional level. The results show the relative importance of student level and institutional factors on study progress.