学、教、研结合培养模式的研究与实践

学、教、研结合培养模式的主体结构为“一、二、三、四、五”:一种基本思想 ;二突出培养目标 ;三开放培养计划 ;四合一课程体系 ;五要素培养方式。主体人格和学、教、研结合 ,既是目标性要求 ,又是过程性要求。该模式是观念性系统、制度性系统、行为性系统的有机统一。     

Study on the expression and mutation of human telomeric repeat binding factor ( hTRF1 ) in 10 malignant hematopoietic cell lines

Objective: Detecting the expression and mutation of human telomeric repeat binding factor (hTRF1) in 10 malignant hematopoietic cell line cells on the base of determining its genomic structure and its four pseudogenes to clarify if hTRF1 mutation is one of the factors of the activation of telomerase. Methods: hTRF1cDNA sequences were obtained from GenBank, its genome structure and pseudogenes were forecasted by BLAST and other biology information programs and then testified by sequencing. Real-time RT-PCR was used to detect the expression of hTRF1mRNA in 10 cell line cells, including myelogenous leukemia cell lines K562, HL-60, U-937, NB4, THP-1, HEL and Dami; lymphoblastic leukemia cell lines 6T-CEM, Jurkat and Raji. Telomerase activities of cells were detected by using telomeric repeat amplification (TRAP)-ELISA protocol. PCR and sequencing were used to detect mutation of each exon of hTRF1 in 10 cell line cells. Results: hTRF1 gene, mapped to 8q13, was divided into 10 exons and spans 38.6 kb. Four processed pseudogenes of hTRF1 located on chromosome 13, 18, 21 and X respectively, was named as ψhTRF1-13, ψhTRF1-18, ψhTRF1-21 and ψhTRF1-X respectively. All cell line cells showed positive telomerase activity. The expression of hTRF1 was significantly lower in malignant hematopoietic cell lines cells (0.0338, 0.0108:_0.0749) than in normal mononuclear cells (0.0493, 0.0369:_0.128) (P=0.004). But no significant mutation was found in all exons of hTRF1 in 10 cell line cells. Four variants were found in part of intron 1, 2 and 8 of hTRF1. Their infection on gene function is unknown and needs further studies. Conclusion: hTRF1 mutation is probably not one of the main factors for telomerase activation in malignant hematopoietic disease. Project supported by the National Basic Research Program (973) of China (No. 2002CB713700) and the National Natural Science Foundation of China (No. 39870339)     

Testing Factorial Invariance With Unbalanced Samples

In testing the factorial invariance of a measure across groups, the groups are often of different sizes. Large imbalances in group size might affect the results of factorial invariance studies and lead to incorrect conclusions of invariance because the fit function in multiple-group factor analysis includes a weighting by group sample size. The implication is that violations of invariance might not be detected if the sample sizes of the 2 groups are severely unbalanced. In this study, we examined the effects of group size differences on results of factorial invariance tests, proposed a subsampling method to address unbalanced sample size issue in factorial invariance studies, and evaluated the proposed approach in various simulation conditions. Our findings confirm that violations of invariance might be masked in the case of severely unbalanced group size conditions and support the use of the proposed subsampling method to obtain accurate results for invariance studies.     

Social Exclusion and the Hidden Curriculum: The Schooling Experiences of Chinese Rural Migrant Children in an Urban Public School

Since 2001, the Chinese government had passed a series of policies known as ‘the two primary responsibilities’ to allow the rural migrant children to attend urban public schools. However, what the migrant children actually experienced in and after negotiating access to these schools deserves serious attention from educators, scholars and policymakers. Based on prolonged ethnographic fieldwork in a Beijing public school, this study demonstrated three key aspects of exclusions in migrant children’s schooling experiences, namely, (1) access to school, (2) in-class participations and (3) peer interactions, and examined the ‘hidden curriculum’ in the existing school practices that prevented migrant children from integrating successfully in the urban school settings. We found that academic performance lay at the root of social exclusions, but the local educators’ perceptions of migrant children as outsiders, the urban-oriented school curricular and urban children’s involvement (vis-à-vis migrant children’s little involvement) in the extracurricular activities at school as well as the paid supplementary trainings outside school together formed the ‘hidden curriculum’ that led to the marginalization of migrant students in the urban school system.     

开放教育形成性考核成绩的组成及基本考核模式的研究

形成性考核成绩是现代远程开放教育教学过程质量控制的一个重要途径。本文先就形成性考核成绩的两大组成,即平时学习态度、平时作业的权重,进行了论证,在实践经验总结和分析的基础上,构建了形成性考核成绩具体组成、实施细则、评定办法三个基本模式,试图到达既实际又便于操作之目的。     

Academic motivations of Yi youths in China: Classmate support and ethnic identity

To enhance the academic achievements of Yi ethnic minority youths in rural school settings, the authors examined the effect of classmate support and the meditating role of ethnic identity in promoting their academic motivation. Cross-sectional survey data were collected from Yi youths sponsored by a philanthropic organization to attend local schools in Liangshan, rural China (n?=?657; 7–12 years old; 52% boys). Results of structural equation modelling showed that classmate support positively affected ethnic identity-commitment and ethnic identity-exploration, which then had positive impacts on three academic motivation outcomes: intrinsic motivation, extrinsic motivation-external and identified regulation, and extrinsic motivation-introjected regulation. The mediating effects of ethnic identity-exploration and ethnic identity-commitment were statistically significant, except for the pathway from classmate support to extrinsic motivation-introjected regulation via ethnic identity-commitment. The authors found that ethnic identity can be facilitated through building supportive classroom environment for positive academic motivations in Yi youths. Cross-cultural significance of this study is also discussed.     

培养学习能力,提高信息素养--剖析开放教育英语本科"成功指南二"的课程设计

本文剖析开放教育英语本科“成功指南2”的课程设计，从对开放教育学生在素质方面的培养角度出发．提出了该课程的设计注重培养学生的学习能力和获取信息的能力，符合开放教育的特点。     

优化"语言表达"复习课教学结构

高考中“语言表达”(高考第六大题)这个板块有一个特点:学生进行强化训练,难保都能拿到高分;学生不怎么训练,可能也会拿到一点分数。这个特点可能会使一些学生对“语言表达”的复习产生错误的认识,从而影响复习的积极性。于是就产生这样一个问题:在“语言表达”复习课上,如何保证把每一分钟都用在刀刃上,保证教师高投入,学生也高收效?笔者认为在“语言表达”复习课中,应力求让每位学生通过实践认识事物(知识)的个性,再掌握事物的共性,进而形成理论,又返过来指导新的实践,在这一学习过程中,把知识内化为自己的能力。这就要优化“语言表达”复…     

Science concept learning by English as second language junior secondary students

Recent Chinese migrant students from Taiwan studying science in two Australian secondary schools were found to explain the meanings of selected science concept labels in English by translating from Chinese. The research strategy involved interviewing the students concerning their recognition and comprehension of the science concept labels firstly in Chinese and then in English. Mean recognition and comprehension scores were higher in Chinese than in English, with indications that Chinese language and science knowledge learnt in Chinese deteriorated with increasing time of residence in Australia. Rudimentary signs of the students being able to switch between Chinese and English knowledge bases in science were also found. Implications for teaching science to ESL students and suggestions for further research are discussed.     

网络环境下混合式教学的探索与实施——高校"现代教育技术"公共课教学改革案例

各级学校对教师现代教育技术技能要求的不断提高也对高师院校现代教育技术公共课的教学提出了更高的要求,但由于这门课程带有公共课的性质,多年来教学效果一直不理想。基于此,本文提出了网络环境下混合式教学的探索与实施的改革思路,经过一年多的实践,构建了高师院校"现代教育技术"公共课教学新模式。