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971.
972.
Ajay Kumar D. H. Shah M. G. R. Rajan U. R. Thakare S. M. Sharma 《Indian journal of clinical biochemistry : IJCB》1992,7(2):159-164
An external quality assessment was conducted to assess the performance of various laboratories for RIA of thhyroid related
hormones in two phases. In the first phase thirty five laboratories participated. At the end of first phase a meeting cum
workshop was organised to discuss the results of first phase, difficultires faced by the participants and pinpoint the short
oming. A second phase was then initiated with an objective of improvement in the performance, if any, where twelve samples
from four pools were distributed to twenty four laboratories who participated for the second phase. The overall return of
the results increased significantly from 71.8% (1586/2208) for the first phase to 92.4% (732/792) for the second phase. The
inter laboratory %CV for T3, T4 and TSH were lower during the second phase (30.6%, 19.0% and 31.6% respectively) as compared to those observed during first
phase (36.3%, 22.7% and 52.8% respectively). Similarly, there was an improvement in reproducibility of ALTM as %CV for T3, T4 and TSH decreased from 6.0%, 9.8% and 13.4% respectively to 4.5%, 4.6% and 8.5% respectively. The individual performances
of the participating laboratories viz. bias, variability of bias and imprecision also showed a trend towards improvement as
percent laboratories having desirable or acceptable results for T3, T4 and TSH increased from 10.7%, 60.7% and 0.0% respectively to 20.8%, 66.7% and 22.2% respectively. External quality assessment
thus appears to be beneficial in assessing the performane of a laboratory in comfparison with other laboratories and indeed
helps in improving the performance. 相似文献
973.
S. K. Bansal H. N. Pandey A. Bansal L. D. Joshi 《Indian journal of clinical biochemistry : IJCB》1992,7(2):179-184
Circadian rhythm of serum glucose, pyruvate, lactate and lactate dehydrogenase (LDH) was studied in normal healthy young volunteers
at the onset (I Group, 7 cases) and peak (II Group, 8 cases) of winters in India with highly varied temperature. There was
a significant difference, in the circadian rhythm of glucose, pyruvate and lactate dehydrogenase (LDH) of the two groups.
A clockwise shift was observed in acrophase except in serum lactate, which is related to the energy demand in association
with time qualified changes in diurnal activity of the individuals and change in photoperiod. 相似文献
974.
Seema Gupta Rajesh Pandey Ranjan Katyal H. K. Aggarwal R. P. Aggarwal S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71
The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20
male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male
non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples
were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT),
glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino
transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core
of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was
a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in
alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased
oxidative stress and compromised antioxidant defense system in patients with ALD. 相似文献
975.
R. K. Singh A. Bansal S. K. Bansal A. K. Upadhyay V. K. Singh 《Indian journal of clinical biochemistry : IJCB》1992,7(1):61-65
Nychthemeral rhythmicity of urinary copper (Cu) was studied in 40 clinically healthy volunteers and 35 renal stone formers.
A marked diurnal rhythm was noticed in urinary Cu levels in healthy subjects with maximum excretion at 0000 to 0600 hr followed
by a progressive fall during the rest of the period reaching minimum between 1200 to 1800 hr in males and 0600 to 1200 hr
in female volunteers. Similarly, all stone patients exhibited a definite rhythm in urinary Cu with significant amplitude and
acrophases at 2145 hr for males and 2141 hr for female stone formers. However, there was no difference in mean 24-hr Cu excretion
in male and female stone formers, whereas a significant change was observed in case of healthy subjects. Urinary Cu was found
to be significantly increased in renal stone formers in comparison to healthy controls of either sex attributing a significant
role of this overlooked trace mineral in the crystallization and/or activation of either of the process of stone formation
in the renal tubules. 相似文献
976.
Vandana Dixit Ashok V. Kurup A K Gupta O M Kataria G B K S Prasad 《Indian journal of clinical biochemistry : IJCB》1997,12(1):39-43
Lymphatic filariasis caused byWuchereria bancrofti is a major health problem next only to malaria. A study had been conducted to estimate the prevalence of microfilaraemia in a rural endemic community near Raipur. The incidence of microfilaramia in the community was found to be about 14% when studied by night finger prick method. The incidence appears to be more in males as compared to females. The infection rate in vector population i.e.,Culex quinquefasciatus was recorded at a rate of 10%. No relationship could be drawn between the rates of vector and human filarial infections or between the density of vector population and the rate of vector/human infection(s). Prior health education is essential before taking up control and preventive measures in given endemic zone. 相似文献
977.
978.
979.
B. Raman V. Ramachandran M.O. Ahmad M.N.S. Swamy 《Journal of The Franklin Institute》1982,313(6):353-372
This paper discusses a multivariable array whose elements are multivariable homogeneous polynomials which may have missing terms in any of the variables. This array permits one to obtain conditions for the realizability of a driving-point function or a transfer function as a resistively terminated low-pass ladder network. By reac- tance transformations, other forms of ladder structures can be obtained. The case of cascade-separable ladder networks is discussed in detail. 相似文献
980.
Rukmini M. S. Benedicta D'Souza Vivian D'Souza 《Indian journal of clinical biochemistry : IJCB》2004,19(2):114-118
Free radical mediated pathological processes may have a role in schizophrenia. Free radicals (oxy radicals, such as superoxide,
hydroxyl ions and nitric oxide) cause cell injury, when they are generated in excess or when the antioxidant defense is impaired.
Both these processes seem to be affected in schizophrenia. In this study we investigated erythrocyte superoxide dismutase
(SOD) and catalase (CAT) activities as antioxidant enzymes, malondialdehyde (MDA) as a sign of lipid peroxidation in schizophrenic
patients. Activities of superoxide dismutase, catalase and malondialdehyde were greater in patients compared with the control
group which may reflect increased oxidative stress in the brain tissue of schizophrenics. In the patient group erythrocyte
SOD and CAT activities were weakly negative correlated with MDA concentration. These data reveal that antioxidant defense
mechanisms might be impaired in schizophrenic patients. These findings also provide a theoretical basis for the development
of novel therapeutic strategies, such as antioxidant supplementation. 相似文献