Novel distribution pattern of fibrinolytic components in rabbit tissues extract： a preliminary study

Objective: The purpose of this work was to investigate the distribution pattern of fibrinolytic factors and their inhibitors in rabbit tissues. Methods: The components of the fibrinolytic system in extracts from a variety of rabbit tissues, including tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1), plasminogen (Plg), plasmin (Pl) and α2 plasmin inhibitor (α2PI), were determined by colorimetric assay. Results: The tissue extracts in renal, small intestine, lung, brain and spleen demonstrated strong fibrinolytic function, in which high activity of tPA, Plg and Pl was manifested; whereas in skeletal muscle, tongue and stomach, higher activity of PAI-1 and α2PI showed obviously. Also excellent linear correlations were found between levels of tPA and PAI-1, Pl and α2PI, Plg and Pl. In related tissues, renal cortex and renal marrow showed distinctly higher activity of tPA and lower activity of PAI-1, with the levels of Plg and Pl in renal cortex being higher than those in renal marrow, where the α2PI level was higher than that in renal cortex. Similarly, the levels of tPA, Plg and Pl in small intestine were higher than those in large intestine, but with respect to PAI-1 and α2PI, the matter was reverse. In addition, the fibrinolytic activity in muscle tissue was lower, however, the levels of tPA, Plg, and Pl in cardiac muscle were obviously higher than those in skeletal muscles, and the levels of PAI-1 and α2PI were significantly lower than those in skeletal muscle. Conclusion: Our data demonstrate that a remarkable difference of the fibrinolytic patterns exists in rabbit tissues, which has probable profound significance in understanding the relationship between the function of haemostasis or thrombosis and the physiologic function in tissues.     

幼儿换班引发的心理问题及其千预策略

由于幼儿父母工作调动、家庭地址变迁或幼儿园班级调整等原因,幼儿换班已经成为一种常见的现象.换班包括幼儿园内换班和幼儿园间换班.其中,幼儿园内换班主要是指在幼儿园内进行的班级调整,部分幼儿从原来的班级调入新的班级,幼儿园间换班是指幼儿离开原来的幼儿园进入新幼儿园的新班级,本文主要论述的是幼儿园内换班(简称"换班",下同).     

基于舆情客体与本体剥离的重大突发事件网络舆情本体演化强度研究

[目的 /意义]重大突发事件网络舆情在传播过程中往往会出现不同的主题,而微博用户对不同主题的表达和关注也会直接影响网络舆情的传播速度和规模以及舆情事件的走向。针对重大突发事件的微博用户主题演化分析有助于应急管理部门更好地理解重大突发事件的发展轨迹以及公众在不同阶段的关注点,以便采取有效应对措施。[方法 /过程]以网络舆情信息特征为立足点,辅以自然语言处理技术将舆情信息客体与本体进行剥离,结合重大突发事件特征,创新性提出以舆情客体信息为参照基线的舆情本体演化强度来反映微博主题演化趋势。[结果 /结论 ]研究结果表明,面向网络舆情信息本体的主题分析,与网络舆情实际发展演化趋势更加贴近,对主题内容的揭示也更加全面。同时研究思路也对现有网络舆情主题分析的研究方法中单一求助于自然语言处理技术的优化与更新具有一定启示意义。     

高校固定资产实物验收管理的几点体会

通过建立健全的实物验收管理办法和验收规范、统一验收标准、加强内部沟通的手段,强化了实物验收管理环节,有效提高了用户对仪器设备主要性能指标的掌握程度和自我保护意识,确保了引进仪器设备的质量,最终将为有效提高固定资产的使用效益起到积极作用。     

论教育自由

自由与控制是对立统一的关系,学生的发展需要自由也需要控制,无论是自由还是控制,其合理性的标准是促进学生的发展和幸福。教育自由的实现需要具备一些条件,教育者自身要具有自由,培养学生自由能力,提高自律水平,通过建立公正的制度保障自由。     

新疆文化旅游发展路径选择

文章从新疆"十二五"期间旅游发展规划和文化旅游特征进行分析,充分挖掘新疆文化旅游的内涵。文本以新疆独特的地缘、人文优势为基础,研究了当前新疆文化旅游发展的状况,存在的问题以及发展趋势,并建构新疆文化旅游发展具体路径,实现新疆旅游业培育成为新疆经济的战略性支柱产业,为新疆跨越式发展和长治久安服务。     

“酶的特性”的探究性教学设计

本节教学中注重探究性学习的尝试,通过诱思探究、以不同形式如语言表述、表格设计和简笔画设计分析等来探究影响酶活性的条件,设计教学的各个环节。     

Resistance partial factor and reliability of cast ball-and-socket support joint

Considering the uncertainty of material performance, geometric characteristic and analysis method, the analysis of statistical parameters of the resistance of cast ball-and-socket support joints and the reliability analysis are carried out by JC method (improved first-order second-moment method) based on the relevant experimental data. Results show that the resistance partial factor of the joint increases with the increase of the reliability index. The resistance partial factors are suggested corresponding to the reliability index under different load combinations. Moreover, the suggested resistance partial factor is adopted in reliability design, and it is found that the reliability index of the joint is larger than the target reliability index. The optimal load combination is the one in which live load plays an important control role. Finally, based on the suggested resistance partial factors, the reliability analysis of cast ball-and-socket support joints of a project is conducted.     

国家重点实验室建设现状与思考

国家重点实验室是我国贯彻科教兴国战略的一项重要举措,论文对目前国家重点实验室的布局、队伍建设、研究水平、经费支持、运行管理等几个方面进行了统计分析。叙述了国家重点实验室发展中存在的问题,并以作物种质创新与资源利用国家重点实验室培育基地建设经验为例,对重点实验室如何定位、特色凝练、创新管理及发挥科研成果在经济建设中的作用等提出了思考意见。     

浅谈开放实验室对物流工程专业研究型人才培养

开放实验室是培养学生创新能力和综合素质的重要基地之一,实验室开放训练是物流工程专业研究型人才培养能力获取的重要环节。物流工程专业学生通过在开放实验室进行专业基础技能、专业综合设计、自选课题型综合训练及科研创新型实验等不同程度的实验,可获得关于物流工程专业的基础理论、知识和技能,以及综合设计能力、前瞻能力和具有独立获取知识、提出问题、分析问题和解决问题的基本科研能力。