Yangxueqingnao particles inhibit rat vascular smooth muscle cell proliferation induced by lysophosphatidic acid

Objective: To observe the effect of Yangxueqingnao particles on rat vascular smooth muscle cell (VSMC) proliferation induced by lysophosphatidic acid (LPA). Methods: The amount of3H-TdR (3H-thymidine) admixed in cultured rat VSMC was measured and mitogen-activated protein kinase (MAPK) activity and lipid peroxidation end product malondialdehyde (MDA)content of the VSMC were assayed. Results: 1×10-9, 1×10-8, 1×10-7 mol/L LPA in a concentration dependent manner, induced the amount of 3H-TdR admixed, MAP kinase activity, and MDA content of the cultured rat VSMC to increase. However, 5%, 10%,and 15% Yangxueqingnao serum preincubation resulted in a decrease of 23.0%, 42.0%, and 52.0% (P＜0.01) respectively in the amount of 3H-TdR admixed, a decline in VSMC MAP kinase activity of 13.9% (P＜0.05), 29.6% (P＜0.01), and 48.9% (P＜0.01)respectively, and also, a decrease in MDA content of VSMC of 19.4%, 24.7%, and 43.2% (P＜0.01) respectively, in the 1×10-7mol/L LPA-treated VSMC. Conclusions: LPA activates the proliferation and lipid peroxidation of VSMC in a concentration dependent manner. The LPA-induced VSMC proliferation is related to the activity of MAP kinases, enzymes involved in an intracellular signalling pathway. The results of the present study showed that Yangxueqingnao particles can effectively inhibit LPA-induced VSMC proliferation, MAP kinase activation, and reduce lipid peroxidative lesion.     

Oseen流动中粘性对自由表面波的影响

Based on the complex dispersion relation for the two-dimensional free-surface waves generated by a moving body in the steady Oseen flows, the effect of viscosity on wavelength and wave amplitude was investigated by means of an asymptotic method and a numerical analysis. A comparison between the asymptotic and numerical analysis for the viscous decay factor demonstrates the validity of the perturbation expansions for the wave profile. The numerical result shows that the wavelength of viscous wave is slightly elongated in comparison with that of inviscid wave.     

张恨水作品在新闻传媒中的身份确论

张恨水作为报人小说家，其新闻观念与艺术追求之结合、其作品与新闻传媒的结缘，丰富了我国文学史与新闻史的研究；其作品对文学性与新闻性的自觉或不自觉的契合和嫁接，确立了张恨水作品在新闻传媒中的身份；在二十世纪上半期的中国，无论是张恨水选择了新闻传媒，抑或是新闻传媒选择了张恨水，都是偶然中的一种历史必然。     

论毛坯误差复映与控制

本文论述了毛坯误差复映的形成规律和定量分析方法，阐述了毛坯误差复映规律的应用，提出了减少毛坯误差复映的工艺措施。     

论邓小平对科学发展观的贡献

邓小平同志在半个多世纪的中国革命和建设中，继承和发展了毛泽东思想，创立了中国特色社会主义的发展理论．带领全党和全国各族人民开创了改革开放和社会主义现代化建设的新局面，为我党在新世纪、新阶段确立的科学发展观做出了伟大的历史性贡献。     

对我国现代远程教育发展现状的思考

随着社会的发展、科学技术的进步以及知识经济时代的来临,现代远程教育在我国高等教育尤其是成人高等教育和职业教育中的作用越来越重要。本文分析了远程教育的特点,并针对我国现代远程教育发展中存在的一些问题,提出了相应的对策。     

Experiential learning in doctoral training programmes: fostering personal epistemology through collaboration

There has been increasing recognition for the need to reform doctoral training practices to foster students’ personal epistemology. This study describes the design and evaluation of a learning experience designed to help students understand the scholarly publication process. Firstly, this study discusses the design of the learning experience, describing the collaborative process of writing an interdisciplinary publication using both online and face-to-face learning. Secondly, this study evaluates the effectiveness of the learning experience by examining students’ reflections. We show that participation in the learning experience helped students to develop their academic writing proficiency, collaboration and teamwork, intercultural competence, and ability to engage in reflective practice. Importantly, we show that each student also created more individualised knowledge, gaining insight into how they and others think. This study, therefore, demonstrates that personal epistemology can be fostered through collaboration in a doctoral writing group context.     

如何同大学生建立良好的师生关系

本文根据个人的教育工和体会,讲述了在当今信息社会建立良好的新型师生关系,教师必须摆脱“我教你学”的传统教育观念,转变角色,师生平等对话。进而牢固树立“学生本位”思想,并以高尚的师德和炽烈的师爱去进行教育与指导学生学习和研究,从教育观点和教育行为的转变中建立良好的新型师行关系。文章最后小结归纳了全文的观点,并强调教师的观念、品格及综合素质是建立良好师生关系的关键。     

铝不能与氧化镁发生反应吗--谈金属与氧气反应趋势顺序的应用

有一道在中学化学中流传已久的习题:不能用铝热反应制备的金属是(B)。A.CrB.MgC.MnD.V显然,这类试题的答案是以金属活动性顺序为依据的。其实,金属活动性顺序是按水溶液中金属单质与其对应金属阳离子所组成电极的标准电极电位由小到大的顺序排列而成的,只能作为水溶液中某些反应的判据。铝热反应的判据应该是金属与氧气反应的趋势顺序,该顺序可以由金属与氧气反应生成相应氧化物的Ellingham图(如图1)得到。