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31.
Jai Prakash Balraj Mittal Shally Awasthi C. G. Agarwal Neena Srivastava 《Indian journal of clinical biochemistry : IJCB》2013,28(2):158-163
Obesity is risk factor for insulin resistance, diabetes, and other chronic diseases. Adiponectin, an adipose-specific protein with antiatherogenic and antiinflammatory effects, were found to be associated with obesity, type 2 diabetes, and insulin resistance. Our aim to identify possible relationships between circulating adiponectin and obesity as well as obesity related phenotypes. A total of 642, obese and non-obese individuals were included in this cross-sectional study. Hormone and glucose levels were estimated using standard protocols. The adiponectin levels showed a significant decrease with increasing quartiles of insulin resistance index. Subjects in lowest quartile of adiponectin level had a significantly higher risk than those in the highest quartile, with higher body mass index, waist circumference, blood pressure, percentage body fat, fat mass, fasting insulin, insulin resistance index, total cholesterol (p < 0.001), low density lipoprotein–cholesterol (p = 0.001), very low density lipoprotein–cholesterol (p = 0.002), and Triglyceride (p = 0.002). The present study indicates that adiponectin is significantly associated with obesity, insulin resistance and other obesity related phenotypes. 相似文献
32.
Sutirtha Chakraborty Anindya Dasgupta Harendra Nath Das Om Prakash Singh Asok Kumar Mandal Nikhiles Mandal 《Indian journal of clinical biochemistry : IJCB》2009,24(2):194-197
Oxidative stress has been found to play important role in several neuropsychiatric diseases including Obsessive Compulsive
Disorder. A longitudinal case control study was conducted to evaluate the oxidative stress in 30 newly diagnosed obsessive
compulsive disorder patients and same number of control patients. Serum thiobarbituric acid reacting substances, plasma ascorbate
were assessed to evaluate oxidative stress and Yale Brown obsessive compulsive scale for disease severity before and after
treatment with Fluoxetine at the average dosage of 40 mg/day. Improvement in Yale Brown obsessive compulsive scale score by
about 43% after 12 weeks treatment was associated with significantly decreased thiobarbituric acid reacting substances and
increased plasma ascorbate values (p < 0.05). The newly diagnosed obsessive compulsive disorder patients had higher serum
thiobarbituric acid reacting substances as well as a lower plasma ascorbate levels than the control population. Thus, the
present study suggested a significant role of oxidative stress in obsessive compulsive disorder and showed that a successful
treatment with Fluoxetine not only improves the clinical scenario but also reduces the oxidative stress that may further improve
the prognosis of the disease. 相似文献
33.
Savita Singh Tenzin Kyizom K. P. Singh O. P. Tandon S. V. Madhu 《Indian journal of clinical biochemistry : IJCB》2008,23(4):365-368
A distinguishable feature of type 2 diabetes besides hyperglycemia and deranged lipid profile is an impaired insulin secretion,
peripheral insulin resistance and obesity which has become a major health concern worldwide. India with an estimated 31million
diabetics in 2000 and 79mllions by the yr 2030 has the highest number of type 2 diabetics in the world. In this study, we
aimed to see if yoga-asanas and pranayamas have any influence in modifying certain biochemical parameters. Sixty patients
of uncomplicated type 2 diabetes (age 35–60 yrs of 1–10 yrs duration) were divided into two groups: Group 1 (n=30): performed
yoga along with the conventional hypoglycemic medicines and group 2 (n=30): patients who only received conventional medicines.
Duration of the study was 45 days. Basal recordings of blood glucose (fasting and post-prandial), lipid profile and serum
insulin were taken at the time of recruitment and the second reading after forty five days. Results showed a significant improvement
in all the biochemical parameters in group 1 while group 2 showed significant improvement in only few parameters, thus suggesting
a beneficial effect of yoga regimen on these parameters in diabetic patients. 相似文献
34.
Mungli Prakash Jeevan K. Shetty Sambit Dash Bijay K. Barik Abhirup Sarkar Sharanabasappa M. Awanti Ravindra Prabhu 《Indian journal of clinical biochemistry : IJCB》2008,23(4):404-406
Total thiol status of plasma, especially thiol groups over protein contributes maximum to the plasma antioxidant status of
the body. Serum protein thiols were found to be decreased in various disease conditions including chronic renal failure patients.
Only few studies determined the levels of urinary protein thiols in disease conditions. The current study was designed to
know the levels of urinary protein thiols in patients with different grades of proteinuria. The study was conducted on urine
of 40 healthy controls and 61 cases with proteinuria. Based on proteinuria cases were further divided into two groups; group
I - microproteinuria (150–300 mg protein/d), 32 cases, group II - frank proteinuria (>300 mg protein/d), 29 cases. Urinary
thiol levels were determined by spectrophotometric method using dithionitrobenzoic acid. A significant decrease (p<0.01) in
urinary thiol in group I and group II cases was observed in present study and this decrease was associated with proteinuria. 相似文献
35.
H. Surya Prakash Rao 《Resonance》1998,3(11):82-86
The structure, properties and synthesis of a bowl shaped molecule, which resembles a fragment of fullerene, are described here. 相似文献
36.
Marmar Mukhopadhyay & Madhu Parhar 《British journal of educational technology : journal of the Council for Educational Technology》2001,32(5):543-556
The Multi-channel learning environment is nebulous and incidental configuration where channels reinforce as well as contradict each other. The Multi-channel learning system is a deliberate, planned configuration to create the sync and synergize the power of various media to achieve optimal learning. This articles examines instructional design for the classroom, for self instructional materials, media—and MCLS. 相似文献
37.
38.
This study explored the relationship between school achievement levels and teachers’ expectations, locus of control and efficacy
in four elementary schools in Delta, Mississippi in keeping with the self-fulfilling prophecy theory. Data from surveys of
102 teachers, five focus groups, observations, and secondary information on teachers’ grading pattern were used. Analyses
using t-tests and multiple linear regressions revealed that teachers in high achieving schools tended to exhibit an internal locus
of control and base their expectancies on students’ abilities rather than personal characteristics. School achievement level
was found to be the only significant predictor indicating that high achieving schools had a culture of higher expectations
that affected teachers’ perceptions, motivations, and grading pattern. These findings are substantiated by qualitative assessments. 相似文献
39.
Mohana Kumari Chidananda Deepy Zohmangaihi Sant Ram Shiv Lal Soni Vikas Suri Pankaj Malhotra Ravjit Singh Jassal Jyotdeep Kaur Indu Verma Sadhna Sharma 《Indian journal of clinical biochemistry : IJCB》2021,36(4):485
Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global health problem, India being the second most affected country. The kinetics of antibody response to SARS-CoV-2 in Indian population is not studied yet. To understand serological response in relation to age, gender, time period and severity of disease, Roche Elecsys anti-SARS-CoV-2 test was used which analysed both IgM and IgG. One hundred and three COVID-19 patients were enrolled. Seropositivity was seen in 64% of patients, with 33% at ≤ 7 days, 62% between 8 and 15 days and 81% at ≥ 16 days from the time of admission. Men (65%) showed higher antibody response than women (59%), whereas no difference was observed in seropositivity with respect to age of the patients. Dynamics of antibody responses revealed individual variations. Patients in ICU had higher antibody reactivity with 67% positivity as compared to 60% positivity in non-ICU patients. Kinetics of antibody response during COVID-19 disease varied in relation to gender, age, time period and severity and these factors might play an important role in treatment and control of COVID-19. 相似文献
40.
Gillian King Beata Batorowicz Patty Rigby Margot McMain-Klein Laura Thompson Madhu Pinto 《International Journal of Disability, Development & Education》2014,61(1):44-66
There is a need for psychometrically sound measures of youth experiences of community/home leisure activity settings. The 22-item Self-Reported Experiences of Activity Settings (SEAS) captures the following experiences of youth with a Grade 3 level of language comprehension or more: Personal Growth, Psychological Engagement, Social Belonging, Meaningful Interactions, and Choice & Control. Forty-five youth aged 14–23 years (10 with severe disabilities) completed the SEAS in 160 leisure activity settings. The SEAS has good to excellent internal consistency (Cronbach’s alpha from 0.71 to 0.88) and moderate test–retest reliability (mean scale intra-class correlation coefficient = 0.68), as expected due to changes in activity settings over time. The SEAS was able to differentiate various types of activity settings and participation partners. The SEAS can be used to gain greater understanding of situation-specific experiences of youth participating in various types of recreation and leisure activity settings, including youth with different types of disabilities and those without disabilities. 相似文献