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31.
Gora Dadheech Praveen Sharma Shiv Gautam 《Indian journal of clinical biochemistry : IJCB》2012,27(3):278-283
Reactive oxygen species (ROS) formed in various metabolic reactions cause unlimited damage by attacking and oxidizing the macromolecules. An arsenal of antioxidant substances neutralizes these ROS at various sites of their metabolic cascade, and if disequilibrium exists between the pro and antioxidant system, oxidative stress persists. The present study was undertaken in schizophrenia, to highlight the response and role of some endogenous antioxidants viz. reduced glutathione (GSH), bilirubin, total proteins, albumin and uric acid in scavenging the ROS. The effect of severity of disease, age factor, and substance abuse was also studied. In all, 50 schizophrenics and 50 age and sex-matched controls were enrolled in the present study. Fasting blood samples were drawn for estimating malondialdehyde (MDA), GSH, bilirubin, total proteins, albumin and uric acid in both the groups. The results were statistically analyzed by Z-test and correlated using correlation coefficient (r). The study shows reduction in MDA levels and decline in the level of endogenous antioxidants, but within the normal range. Chronic schizophrenics were at a higher risk of oxidative stress and age and substance abuse seems to worsen the situation. 相似文献
32.
This article reports on the third phase of a larger study that explored the perceptions of teachers about distributed leadership practices for inclusive education (IE) in primary schools involved in IE reform in Bangladesh. The Distributed Leadership Practice for Inclusive Education scale was developed specifically for this study to collect data. Participants for the present study were head teachers and teachers from 308 public primary schools. The results of this study indicate that teachers perceived that distributed leadership practices for IE were present in primary schools in Bangladesh. The findings indicate that teachers' perceptions about distributed leadership practices for IE have a significant positive correlation with their satisfaction about the implementation of IE policy. 相似文献
33.
The purpose of this paper was to investigate Malaysian primary pre-service teachers’ perceptions of students’ disruptive behaviour and their self-reported strategies to prevent and to manage such behaviours. Results indicate that Malaysian pre-service teachers understand disruptive behaviours to be those that disrupt the learning and teaching process. They identified the cause of student disruptive behaviour as factors residing within the individual student. Pre-service teachers here reported preventative strategies in terms of changing teaching strategies and threats to use punishment. When addressing students’ disruptive behaviour, pre-service teachers reported that they would use one-to-one counselling with students and remove tokens or hold back rewards. A discussion regarding the implications for teacher education institutions and future research concludes this paper. 相似文献
34.
35.
The effect of peer feedback for blogging on college students' reflective learning processes 总被引:1,自引:0,他引:1
Reflection is an important prerequisite to making meaning of new information, and to advance from surface to deep learning. Strategies such as journal writing and peer feedback have been found to promote reflection as well as deep thinking and learning. This study used an empirical design to investigate the interaction effects of peer feedback and blogging on college students' reflective thinking skills and their learning approaches. Forty-four first- and second-year undergraduate students participated in the study. Students kept blogs each week throughout a whole semester. Two journals were sampled at the beginning and end of the semester for each student. A repeated measure one-way ANOVA suggested that students' reflective thinking level increased significantly over time; however, peer feedback was found to negatively affect students' reflective thinking skills. The result of the study suggests more carefully designed uses in the future. 相似文献
36.
Everybody is familiar with the ubiquitous term ‘species’. But what is a species? Undeniably, this is one of the most complex dilemmas in the history of biology. There is no other concept in biology as elementary yet controversial as the concept of species. In practice, a species is regarded as the fundamental unit of comparison in all biological disciplines like systematics, evolution, ecology, ethology, physiology, and genetics. However, little agreement exists in the scientific community regarding the nature of species, whether it is a real entity or a cultural artifact, its biological significance or how to delineate a species. This article is a review of the seemingly endless debate on the species concept and its implications. 相似文献
37.
Chitra Upadhyaya Sandhya Mishra P. P. Singh Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2005,20(1):30-34
Serum antioxidant status and peroxidative stress was estimated in 30 pregnant women, their newborn infants and 25 non-pregnant
women. Serum Ascorbic acid, α-tocopherol, retinol & β-carotene levels were found to be significantly reduced and peroxidative
stress was significantly higher in mothers as compared to matched non-pregnant women. Newborn had significantly higher levels
of ascorbic acid as compared to their mother but had significantly lower levels of lipid soluble vitamins. The peroxidative
stress in newborn was found to be significantly less as compared to their mothers. A positive correlation of ascorbic acid
and α-tocopherol levels between mother and newborn reflects that their status in mother does influence the newborn status. 相似文献
38.
39.
J Kato Alice Abraham Ruram S Sekharjit Singh S Bilasini Devi Th Ibetombi Devi W Gyaneshwar Singh 《Indian journal of clinical biochemistry : IJCB》2007,22(1):128-130
The present, study was conducted to determine the level of malondialdehyde (MDA) as an index of free radial induced lipid
peroxidation and antioxidant vitamins-vitamins A, vitamin C and vitamin E in 75 confirmed cases of urolithiasis. Significantly
high level of MDA (p<0.001) with significantly low levels of vitamin E (p<0.001) and vitamin A (p<0.001) with no significant
decrease in vitamin C (p>0.05) were observed in the plasma of urolithiasis cases as compared to normal controls. In conclusion,
it appears that a role of lipid peroxidation and oxidative function exists in the pathogenesis of urolithiasis. But, the exact
mechanism how this occurs remains to be elucidated. 相似文献
40.
Ritu Sharma Mridula Mahajan Ravi Kant 《Indian journal of clinical biochemistry : IJCB》2004,19(1):10-13
Serum total lipids (cholesterol and triglyceride), lipoproteins (VLDL, LDL and HDL) and Apolipoprotein-B levels of normal
healthy individuals (n=25) and coronary artery disease patients (n=25) were estimated. The objective of the present study
was to ascertain the role of apo-B in causation and inheritance of coronary artery disease. It was observed that on an average
serum total cholesterol and triglyceride more than 200 mg/dl bring the individuals to a risk of coronary artery disease (CAD)
irrespective of the age. CAD patients achieved this value at an early age (35–45 years). Similarly VLDL and LDL levels were
found to be significantly raised in CAD patients when compared to that of age matched normal individuals, with patients achieving
risk values at an early age. HDL levels were found to be significantly lower in CAD patients as compared to normal individuals.
Serum apo-B levels were significantly raised in CAD patients as compared to age matched normal individuals. Patients with
positive family history of CAD had raised serum apo-B levels than those having negative family history. A positive coefficient
of correlation was observed between serum apo-B and LDL levels suggesting that more the number of Apo-B particles, more will
be the synthesis of atherogenic particle (LDL). Patients with negative family history had serum apo-B levels closer to those
of normal individuals and in these individuals HDL levels were found to be significantly lowered, suggesting that loss of
scavenger role of HDL could be the risk factor responsible for the causation of CAD in these patients, with negative family
history of coronary artery disease. 相似文献