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341.
Novel on-demand droplet generation for selective fluid sample extraction   总被引:1,自引:0,他引:1  
Lin R  Fisher JS  Simon MG  Lee AP 《Biomicrofluidics》2012,6(2):24103-2410310
A novel microfluidic device enabling selective generation of droplets and encapsulation of targets is presented. Unlike conventional methods, the presented mechanism generates droplets with unique selectivity by utilizing a K-junction design. The K-junction is a modified version of the classic T-junction with an added leg that serves as the exit channel for waste. The dispersed phase fluid enters from one diagonal of the K and exits the other diagonal while the continuous phase travels in the straight leg of the K. The intersection forms an interface that allows the dispersed phase to be controllably injected through actuation of an elastomer membrane located above the inlet channel near the interface. We have characterized two critical components in controlling the droplet size-membrane actuation pressure and timing as well as identified the region of fluid in which the droplet will be formed. This scheme will have applications in fluid sampling processes and selective encapsulation of materials. Selective encapsulation of a single cell from the dispersed phase fluid is demonstrated as an example of functionality of this design.  相似文献   
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This paper reports on a pilot project carried out between September 1989 and June 1990 at a large college of Further and Higher Education. Using Interactive software based on Repertory Grid Techniques, the authors monitored the progress of a group of students undertaking theflrst year of the Diploma In Nursing (University of London). The primary focus was on how the students were reacting to the course as a whole and to Illuminate Individual difficulties and concerns, which could then be fed back to the course team. It was hoped that the complete process would provide a unique picture of how individual perceptions and responses changed throughout the year.

The authors explain how the software was used, the data analysed, and how the feedback to students and tutors was managed. The prime purpose of the activity was to gain insights into how the technique could be most effectively used across a wide range of courses within the college and to determine whether it was feasible for students to use each other for reflective analysis and discussion of grids. Such an approach should provide useful Information both to course providers and evaluators.  相似文献   

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As more and more information is made available in electronic formats, ensuring reliable access to that information over time is becoming a concern for acquisitions and collection management personnel in all types of libraries. This paper looks at the current situation regarding the availability of monographs, serials, government publications, and web-based information. Possible resolutions must be viewed from a library-wide basis since the situation impacts all of us.  相似文献   
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This study investigates policy issues surrounding the implementation and assessment of 2-1-1 information and referral services. More specifically, the study explores the benefits that users receive from 2-1-1 referral services that are distinct from the actual social assistance provided by various service agencies; what policymakers should consider when funding and implementing 2-1-1 services; and the operational structure and interagency relationships that can maximize the benefit of the referral service to both individuals and existing social service agencies. Researchers conducted an extensive literature review and case study to examine dimensions of service performance, benefit–cost, and user outcomes of 2-1-1 services. This study further identifies potential measures and protocols for developing a holistic assessment program that goes beyond the reporting of quantitative inputs and outputs associated with a 2-1-1 agency. The centerpiece of this study is the creation of a logic model that identifies benefits and costs at three different levels: the individual, organizational, and societal. In addition, the model incorporates the dimension of time in order to distinguish between short-, medium-, and long-term benefits. Thus, the model provides a basis for incremental and flexible assessment of service performance that can lead to the creation of a culture of continuous improvement and ongoing evaluation for 2-1-1 services.  相似文献   
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For all of its apparent success, evangelical-Christian publishing has gone largely unnoticed by the book-publishing world and now finds itself confronted by several challenges. This article provides an overview of the development of evangelical-Christian Moody helped in its launch, and of changes in the way Christian books are distributed. While these changes intersect those in general bookselling, they are also unique in several ways.  相似文献   
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