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James Arthur Phillips 《College Teaching》2013,61(3):250-251
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David Phillips 《牛津教育评论》2013,39(1):121-129
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ABSTRACT This article reports the initial findings of a study of the cohort of students who entered Liverpool John Moores University, England, to study women's studies in the autumn of 1994, basing its focus on the survey carried out as soon as the students entered the University and the in-depth interviews carried out later in that semester. The work proceeded within the tradition of grounded theory research and endeavoured to avoid prepared hypotheses in order to allow the themes to emerge from the students' answers. From the initial findings, the very strong emphasis on the salience of the students' choice of women's studies and the experiential importance of identity as a concept was striking. The article debates the theoretical difficulties in the theorising of identity in relation to the empirical, existential project of the students. 相似文献
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Michael C. Motal Daniel A. Klaus Diana Lebherz-Eichinger Bianca Tudor Thomas Hamp Marion Wiegele Rudolf Seemann Claus G. Krenn Georg A. Roth 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(1):90-96
Introduction
Vaspin (visceral adipose tissue-derived serpin) was first described as an insulin-sensitizing adipose tissue hormone. Recently its anti-inflammatory function has been demonstrated. Since no appropriate data is available yet, we sought to investigate the plasma concentrations of vaspin in sepsis.Materials and methods
57 patients in intensive care, fulfilling the ACCP/SCCM criteria for sepsis, were prospectively included in our exploratory study. The control group consisted of 48 critically ill patients, receiving intensive care after trauma or major surgery. Patients were matched by age, sex, weight and existence of diabetes before statistical analysis. Blood samples were collected on the day of diagnosis. Vaspin plasma concentrations were measured using a commercially available enzyme-linked immunosorbent assay.Results
Vaspin concentrations were significantly higher in septic patients compared to the control group (0.3 (0.1-0.4) ng/mL vs. 0.1 (0.0-0.3) ng/mL, respectively; P < 0.001). Vaspin concentration showed weak positive correlation with concentration of C-reactive protein (CRP) (r = 0.31, P = 0.002) as well as with SAPS II (r = 0.34, P = 0.002) and maximum of SOFA (r = 0.39, P < 0.001) scoring systems, as tested for the overall study population.Conclusion
In the sepsis group, vaspin plasma concentration was about three-fold as high as in the median surgical control group. We demonstrated a weak positive correlation between vaspin and CRP concentration, as well as with two scoring systems commonly used in intensive care settings. Although there seems to be some connection between vaspin and inflammation, its role in human sepsis needs to be evaluated further.Key words: adipocytokine, inflammation, vaspin, CRP, intensive care 相似文献28.
Selection medium is important in sperm isolation for assisted reproductive technologies. Contrary to the naturally occurring human cervical mucus which has a high viscosity, most current practices for motility based sperm selection use a low viscosity medium. In this study, we used a microfluidic device to assess the effects of high viscosity media made with hyaluronic acid (HA) and methyl cellulose (MC) on bovine and human sperm motility and viability (sperm transferred directly from cryoprotectant). The microfluidic penetration test, viability, and motility were compared for sperm swimming in both HA and MC media with about 20cp viscosity (measured at 20 °C). Our resulted indicate that MC medium resulted in a significantly higher number of viable bovine sperm penetrating the medium as compared to HA. Furthermore, MC resulted in the selection of a sperm subpopulation with a 274% increase in sperm viability in comparison to the raw semen, while HA increased viability by only 133%. In addition to viability, bovine sperm motility parameters were significantly higher in the MC medium as compared with HA. Experiments with human sperm swimming in MC indicate that sperm swim slower and straighter at higher viscosities. In conclusion, the results indicate that in a micro-confined environment representative of the in vivo environment, MC is a preferred high viscosity medium to ensure the highest concentration of motile and viable sperm. 相似文献
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Marion Dresner Corinne Handelman Steven Braun Gretchen Rollwagen-Bollens 《Environmental Education Research》2015,21(7):991-1010
We conducted surveys of adults participating in municipally sponsored volunteer events in the Portland, OR metropolitan area in order to understand the range of attitudes and behaviors associated with volunteer work. We sampled 172 individuals in 18 events from February to June 2012. Principal components and factor analyses of survey responses identified three groups based on annual frequency of participation in stewardship events: first-time volunteers, mid-level volunteers (3–10 events per year), and frequent volunteers (>10 events per year). Our analyses revealed three main factors that explained the variation in survey response for the three volunteer groups: environmental identity, private pro-environmental behavior, and civic engagement. All three factors were positively correlated with frequency of participation in stewardship events, with the most frequent volunteers indicating the highest degree of attention to environmental issues, environmental identity, and self-reported pro-environmental behaviors. Frequent volunteers were more likely to feel personally attached to their local environment, believe that their efforts help solve environmental problems, and enjoy being part of community efforts. These results suggest that stewardship activities provide opportunities for volunteers to interact with others while working collectively toward restoring and maintaining parks, which may contribute to more resilient communities. 相似文献