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51.
Tunable pores (TPs) have been used for resistive pulse sensing of 1 μm superparamagnetic beads, both dispersed and within a magnetic field. Upon application of this field, magnetic supraparticle structures (SPSs) were observed. Onset of aggregation was most effectively indicated by an increase in the mean event magnitude, with data collected using an automated thresholding method. Simulations enabled discrimination between resistive pulses caused by dimers and individual particles. Distinct but time-correlated peaks were often observed, suggesting that SPSs became separated in pressure-driven flow focused at the pore constriction. The distinct properties of magnetophoretic and pressure-driven transport mechanisms can explain variations in the event rate when particles move through an asymmetric pore in either direction, with or without a magnetic field applied. Use of TPs for resistive pulse sensing holds potential for efficient, versatile analysis and measurement of nano- and microparticles, while magnetic beads and particle aggregation play important roles in many prospective biosensing applications. 相似文献
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Robin Campbell 《Educational studies》1992,18(2):173-183
Williamson & Carrington argued, in a recent edition of Educational Studies, the need for a major investigation of the effectiveness of an apprenticeship approach to reading. This paper considers some of the problems associated with such investigations. It also seeks to clarify some of the terminology in the whole language repertoire before looking in detail at shared reading as an important part of such approaches. The article concludes by suggesting that ethnographic studies are the means by which issues in the teaching and learning of reading may best be clarified, and teachers and children assisted. 相似文献
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Mr Jeffrey P. Dorman Dr Campbell J. McRobbie Dr Barry J. Fraser 《Research in Science Education》1993,23(1):61-67
Much Catholic school and church rhetoric suggests that Catholic schools possess distinctive learning environments. Research into this aspect of Catholic schooling has been hampered by the lack of an appropriate assessment instrument. By drawing on contemporary church literature, the perceptions of personnel involved in Catholic education and existing classroom environment questionnaires, a new instrument was developed to assess student perceptions of classroom psychosocial environment in Catholic schools. The use of this instrument in 64 classrooms in Catholic and Government schools indicated significant differences on some scales. The distinctive nature of Catholic schooling did not extend to all classroom environment dimensions deemed important to Catholic education. Specializations: Catholic education, learning environments. Specializations: conceptual change in students, science teacher professional development, scientific reasoning, learning environments. Specializations: learning environments, science education, educational evaluation, curriculum. 相似文献
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Mark E. Bouton 《Learning & behavior》1982,10(2):233-241
Three experiments with rat subjects were designed to investigate the possibility that an extinguished saccharin aversion might be reinstated if the animals are made ill with lithium chloride (in the absence of saccharin) following extinction. Although reinstatement can be obtained when the unconditioned stimulus is presented following the extinction of other kinds of conditioned behaviors, the present experiments provided no evidence that an extinguished taste aversion can be reinstated. No reinstatement was observed, even when the aversion had been only partially extinguished and when multiple injections of lithium chloride were administered in an attempt to reinstate the aversion. 相似文献
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E. Mark Hanson 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》1981,27(3):247-270
In Third World countries a key to the course of nation-building is the modernization of the organizational and administrative infrastructures which drive the development process. Increasing the operational capabilities, effectiveness, and efficiency of the ministry of education, and hence the quality and quantity of school outcomes, is typically a high priority item in the development plans of a nation. In order to promote the modernization of management activities in ministries, however, it is first essential to understand their existing patterns of operation. Toward this objective, the paper presents a methodological framework for a field study approach to the examination of the working of a ministry of education in Latin America. Several issues are introduced which influence the process of inquiry, such as: (1) examining the impact of historical traditions on contemporary management procedures; (2) exploring concerns for ethics and academic colonialism; (3) distinguishing between anthropological and sociological participant-observation field methods; (4) gathering and analyzing data on complex ministries; and (5) exploring the task of Third World theory building.
Zusammenfassung Einen Schlüssel zum Verlauf des nationalen Aufbaus in der dritten Welt liefert die Modernisierung der organisatorischen und administrativen Infrastrukturen, die den Entwicklungsprozess vorantreiben. Im allgemeinen wird der Verbesserung der Handels-Fähigkeiten, der Wirksamkeit und Effizienz des Bildungsministeriums eine hohe Priorität in den Entwicklungsplänen eines Landes beigemessen. Um jedoch die Modernisierung der Führungsarbeit von Ministerien beschleunigen zu können, müssen zunächst ihre jetzigen Operationsweisen untersucht werden. Zu diesem Zweck wird in diesem Artikel ein methodologischer Rahmen für einen Feldstudienansatz zur Prüfung der Arbeit eines Bildungsministeriums in einem lateinamerikanischen Staat vorgelegt. Verschiedene Fragen, die den Untersuchungsprozeß beeinflussen, werden erörtert, zum Beispiel; (1) die Auswirkung historischer Traditionen auf derzeitige Leitungsverfahren; (2) Grad der Beachtung von Ethik und akademischem Kolonialismus; (3) Unterschied zwischen anthropologischen und soziologischen Methoden zur Beobachtung von Beteiligten in der Praxis; (4) Sammlung und Analyse von Daten über komplexe Ministerien; und (5) die Aufgabe, in der dritten Welt eine Theorie aufzubauen.
Résumé L'un des éléments essentiels de la course à l'intégration nationale, dans les pays du Tiers Monde, est la modernisation des infrastructures administratives et organiques qui guident le processus du développement. L'une des premières priorités à respecter est typiquement le développement des moyens d'action, de la compétence et de l'efficacité du ministère de l'éducation, et par voie de conséquence, la qualité et l'importance des résultats scolaires. Toutefois, afin de moderniser judicieusement les activités du management dans les ministères de l'éducation, il est primordial de comprendre leur mode actuel de travail. Ayant cet objectif en vue, l'auteur de cet article propose un cadre méthodologique permettant d'aborder sur le terrain l'examen du fonctionnement d'un ministère de l'éducation en Amérique Latine. Il expose plusieurs démarches qui influent sur le processus de l'enquête: (1) examiner l'impact des traditions historiques sur les procédés contemporains du management; (2) déterminer les préoccupations relatives à l'éthique et au colonialisme académique; (3) faire la distinction entre les méthodes anthropologiques et sociologiques de l'observation participante sur le terrain; (4) rassembler et analyser les données concernant les ministères complexes; et (5) explorer la tâche de l'élaboration de théories relatives au Tiers Monde.相似文献
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