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381.
We present an innovative course-based undergraduate research experience curriculum focused on the characterization of single point mutations in p53, a tumor suppressor gene that is mutated in more than 50% of human cancers. This course is required of all introductory biology students, so all biology majors engage in a research project as part of their training. Using a set of open-ended written prompts, we found that the course shifts student conceptions of what it means to think like a scientist from novice to more expert-like. Students at the end of the course identified experimental repetition, data analysis, and collaboration as important elements of thinking like a scientist. Course exams revealed that students showed gains in their ability to analyze and interpret data. These data indicate that this course-embedded research experience has a positive impact on the development of students’ conceptions and practice of scientific thinking.  相似文献   
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To carry out effective teaching/learning processes, lecturers in a variety of educational institutions frequently need support. They therefore resort to advice from more experienced lecturers, to formal training processes such as specializations, master or doctoral degrees, or to self-training. High costs in time and money are invariably involved in the processes of formal training, while self-training and advice each bring their own specific risks (e.g. of following new trends that are not fully evaluated or the risk of applying techniques that are inappropriate in specific contexts).This paper presents a system that allows lecturers to define their best teaching strategies for use in the context of a specific class. The context is defined by: the specific characteristics of the subject being treated, the specific objectives that are expected to be achieved in the classroom session, the profile of the students on the course, the dominant characteristics of the teacher, and the classroom environment for each session, among others. The system presented is the Recommendation System of Pedagogical Patterns (RSPP). To construct the RSPP, an ontology representing the pedagogical patterns and their interaction with the fundamentals of the educational process was defined. A web information system was also defined to record information on courses, students, lecturers, etc.; an option based on a unified hybrid model (for content and collaborative filtering) of recommendations for pedagogical patterns was further added to the system. RSPP features a minable view, a tabular structure that summarizes and organizes the information registered in the rest of the system as well as facilitating the task of recommendation. The data recorded in the minable view is taken to a latent space, where noise is reduced and the essence of the information contained in the structure is distilled. This process makes use of Singular Value Decomposition (SVD), commonly used by information retrieval and recommendation systems. Satisfactory results both in the accuracy of the recommendations and in the use of the general application open the door for further research and expand the role of recommender systems in educational teacher support processes.  相似文献   
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In this study, we examined the relations between biological maturity status, body mass index, age, and perceptions of adult autonomy support in the context of youth soccer. A total of 70 female and 43 male soccer players, aged 9 - 15 years, completed three adult-specific versions (i.e. mother, father, coach) of the perceived autonomy support subscale from the Interpersonal Style Scale. The participants' percent predicted adult stature was used as an estimate of biological maturity status. Multiple linear regression analyses revealed that advanced maturity status in male players predicted lower perceptions of autonomy support from the coach. Maturity status was unrelated to perceptions of autonomy support from the coach in female soccer players, and paternal and maternal autonomy support in male and female players. Age and body mass index were unrelated to perceptions of adult (i.e. coach, mother, father) autonomy support in male and female players.  相似文献   
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Examination of assessment practices in 54 model programs for early education of handicapped children revealed extreme variability. Only 19 tests were used by at least five programs; only one device was used by over half of the responding programs. Most tests were listed as being used for more than one purpose, but some tests appeared to be used more exclusively than others for a particular purpose. Although the technical adequacy, in terms of norms, validit, and reliability, was reportedly an important factor influencing selection and continued use of tests, analysis of the 19 most commonly used devices revealed that only three were technically adequate. Other methods of assessment also were examined. Implications for model practice are discussed.  相似文献   
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