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91.
Education and Information Technologies - Computational thinking – the ability to reformulate and solve problems in ways that can be undertaken by computers – has been heralded as a...  相似文献   
92.

The onset of inflammatory bowel disease (IBD) involves many factors, including environmental parameters, microorganisms, and the immune system. Although research on IBD continues to expand, the specific pathogenesis mechanism is still unclear. Protein modification refers to chemical modification after protein biosynthesis, also known as post-translational modification (PTM), which causes changes in the properties and functions of proteins. Since proteins can be modified in different ways, such as acetylation, methylation, and phosphorylation, the functions of proteins in different modified states will also be different. Transitions between different states of protein or changes in modification sites can regulate protein properties and functions. Such modifications like neddylation, sumoylation, glycosylation, and acetylation can activate or inhibit various signaling pathways (e.g., nuclear factor-κB (NF-κB), extracellular signal-regulated kinase (ERK), and protein kinase B (AKT)) by changing the intestinal flora, regulating immune cells, modulating the release of cytokines such as interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ), and ultimately leading to the maintenance of the stability of the intestinal epithelial barrier. In this review, we focus on the current understanding of PTM and describe its regulatory role in the pathogenesis of IBD.

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93.
ABSTRACT

This article examines trends and issues surrounding recruiting, funding, and hiring of doctoral physical education teacher education (D-PETE) students and graduates. Sources for this examination were background data collected by Boyce and her colleagues, the existing literature on these topics, and qualitative data gathered from 30 sport pedagogists during one round-table session at the National Association for Kinesiology in Higher Education (NAKHE) conference in January 2015. All three sources indicated the importance of recruiting and funding of students and hiring of graduates to the future of D-PETE programs. A number of paths were identified which sport pedagogists could follow in order to keep D-PETE programs safe and help them flourish. Unfortunately, agreement as to which of these paths the field should take was often in short supply. In the conclusions section, suggestions for future research of recruiting, funding, and hiring are made with the goal of providing data which could lead to sport pedagogists making more informed decisions regarding the future direction of D-PETE.  相似文献   
94.
The levels of support which faculty provide to students have been linked to a number of positive effects on students such as lower rates of attrition, greater satisfaction with college life, enhanced self-concept, improved academic performance and more likelihood of remaining enrolled in college through stressful life periods. There are surely fewer periods of life that are busier than new motherhood. This paper presents research carried out at a higher education institution in the United Arab Emirates. We look at the ways in which faculty interact with new student mothers and employ interviews to explore ways in which faculty acknowledge and offer academic and pastoral support to the new mothers. Their perceptions of students’ coping strategies when they combine motherhood and college studies are reported, and the ways in which faculty navigate college policy which relates to the student mothers. Faculty saw themselves as being extremely supportive and flexible towards new mothers. Whilst undergraduate student motherhood was uncommon in their home countries, it was generally felt that the increased organization, efficiency, time management and resilience witnessed in student mothers were assets to the college community. This study also has wider applicability to faculty support of non-traditional students in other settings.  相似文献   
95.
The article traces the career of Frederick G. Kilgour (1914–2006), who is widely recognized as one of the leading figures in 20th-century librarianship. He founded the Ohio College Library Center (OCLC) and from 1967 to 1981 was its first president and chief executive officer, presiding over OCLC's rapid growth from an intrastate network to an international network. In 1971, under Kilgour's leadership, OCLC introduced an online shared cataloging system and an online union catalog (WorldCat) that is today the world's foremost bibliographic database. In 1978, he created the OCLC Office of Research, and in 1979, under his direction, OCLC launched its online interlibrary loan system. The author of 205 scholarly papers, Kilgour received numerous awards and honors over the course a career that took him from Harvard University Library, to the Office of Strategic Services in World War II, to Yale Medical Library, to OCLC, and finally, to the University of North Carolina at Chapel Hill, where he spent his final years on the faculty of the School of Information and Library Science as a Distinguished Research Professor.  相似文献   
96.
Abstract

In this article, I argue that a key problem for understanding the social ramifications of software is an implicit separation of software programs into two separate elements: expressive aspects, which are seen as socially driven and affectual, and functional aspects, understood as scientific and rational. In order to overcome this binary, I develop an alternative framework that examines the ways software expresses best practices, correct behaviors, and social organization. A key element of this framework is an understanding of software programs as simultaneously rhetorical and tangible objects. Given that Western society is dependent on sociotechnical systems in which software plays a crucial role, understanding the complex ways software expresses normative tasks, practices, and social orders is increasingly important.  相似文献   
97.
Abstract

Although the link between exercise and body image is well documented, the considerable inter-individual variability in this relationship has been largely ignored. Therefore, the aim of the present study was to test the contributions of key body image and exercise-related moderators (age, body mass index (BMI), exercise frequency, trait body dissatisfaction, internalisation of appearance standards, and body surveillance tendencies) in predicting variability in the exercise-body satisfaction relationship. Thirty-seven undergraduate women completed a questionnaire containing the above trait-based measures and then carried a Personal Digital Assistant (PDA) for a 7-day period. Participants were instructed to use the PDA to self-report their state body satisfaction immediately following an exercise session and also when the PDA signalled at each of six random intervals throughout the day. Multilevel modelling revealed a bi-directional relationship between exercise and state body satisfaction. Moreover, post-exercise increases in state body satisfaction were strongest for individuals who were younger and engaged in regular exercise, and weakest for individuals with high BMI and/or the tendency to compare their appearance with others. These findings highlight potential limits on the efficacy of exercise-based therapy for body image disturbances.  相似文献   
98.
Abstract

The objective of this study was to provide anthropometric, physiological, and performance characteristics of an elite international handball team. Twenty-one elite handball players were tested and categorized according to their playing positions (goalkeepers, backs, pivots, and wings). Testing consisted of anthropometric and physiological measures of height, body mass, percentage body fat and endurance ([Vdot]O2max), performance measures of speed (5, 10, and 30 m), strength (bench press and squat), unilateral and bilateral horizontal jumping ability, and a 5-jump horizontal test. Significant differences were found between player positions for some anthropometric characteristics (height and percentage body fat) but not for the physiological or performance characteristics. Strong correlations were noted between single leg horizontal jumping distances with 5-, 10-, and 30-m sprint times (r = 0.51–0.80; P < 0.01). The best predictors of sprint times were single leg horizontal jumping with the dominant leg and the distance measured for the 5-jump test, which when combined accounted for 72% of the common variance associated with sprint ability. In conclusion, performance abilities between positions in elite team-handball players appear to be very similar. Single leg horizontal jumping distance could be a specific standardized test for predicting sprinting ability in elite handball players.  相似文献   
99.
The purpose of this article is to provide details about the beneficial processes the constructivist pedagogy has in the area of teaching science. No Child Left Behind could possibly cause detrimental effects to the science classroom and the constructivist teacher, so this essay tells how constructivist-based teaching influences students and their learning of science.  相似文献   
100.
School science courses have widely varying participation rates across a range of student characteristics. One of the stated aims of the 2006 Key Stage 4 science curriculum reforms in England was to improve social mobility and inclusion. To encourage students to study more science, this reform was followed by the introduction in 2008 of an entitlement to study the three separate sciences at Key Stage 4 for the more highly attaining students. This paper uses longitudinal national data over a five‐year period to investigate the extent and change of participation across science courses at KS4, focusing on student gender and socio‐economic status. It finds that whilst there is some evidence of a move towards a more equitable gender balance for some courses, there is as yet little evidence of substantial change in differential participation rates by socio‐economic status.  相似文献   
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