A novel approach to the dissection of the human knee

The knee is one of the most frequently injured joints of the human body with injuries affecting the general population and the athletic population of many age groups. Dissection procedures for the knee joint typically do not allow unobstructed visualization of the anterior cruciate or posterior cruciate ligaments without sacrificing the collateral ligaments. In many cases, the relationships of the intraarticular structures are lost as dissection systematically removes superficial structures to gain access to deeper structures. The authors present an alternative technique for dissection of the human knee joint that allows maximal visualization of intraarticular structures such as the cruciate ligaments and menisci with minimal disturbance to the tibial and fibular collateral ligaments, thus preserving the relationships of the ligamentous and intraarticular structures. Anat Sci Ed 2:41–46, 2009. © 2009 American Association of Anatomists.     

Concept modeling of tapered thin-walled tubes

This paper presents a method to create concept models for the tapered thin-walled tubes using beam elements and spring elements. Developed concept tapered beam models with different taper angles and cross sections are compared with those detailed models through impact analyses. Important crash results are recorded and compared, and the relatively good agreement is achieved between these analyses. Concept modeling steps are illustrated in detail, and a general concept modeling method for such thin-walled tubes is summarized and presented.     

Theoretical and experimental studies of heat transfer with moving phase-change interface in freezing and thawing of porous potting soil

Soil in a cold region is subject to frequent freezing and thawing cycles. Soil frozen for a prolonged period may cause adverse freeze damage to the plants due to cell dehydration or root cell rupture. It is important to understand the detailed heat transfer behaviors of the freezing and thawing processes to prevent freeze damage, and to devise proper mitigation measures for effective pot planting in cold regions. A theoretical model was developed to analyze the transient moving phase-change interface heat transfer in the freezing and thawing of porous potting soil. The theoretical derivation is based on the assumption that the soil freezes completely at a single temperature. Microscopic poromechanic effects on heat transfer behavior were ignored. The spatial domain of the problem was simplified to a 1 D spherical coordinate system with variation in the radial direction. Green＇s function was applied to solve for the time-dependent body temperature. Experiments were conducted for validation of the theoretical model Reasonable agreement between the theoretical predictions and experimental measurements was obtained. The theoretical model developed can be easily used to determine the sensitivity of various parameters in the freezing/thawing processes, e.g., thermal properties of soil, ambient temperature, and planting pot size.     

Microfluidic fabrication of polymeric core-shell microspheres for controlled release applications

We report a facile and robust microfluidic method to fabricate polymeric core-shell microspheres as delivery vehicles for biomedical applications. The characteristics of core-shell microspheres can be precisely and easily tuned by manipulating the microfluidic double emulsion templates. The addition of a shell can significantly improve the versatility as well as functionality of these microspheres as delivery vehicles. We demonstrate that the nature of the shell material plays an important role in the properties of the core-shell delivery vehicles. The release kinetics is significantly influenced by the material of the shell and other characteristics such as the thickness. For example, by adding a poly(lactic-co-glycolic acid) (PLGA) shell to an alginate core, the encapsulation efficiency is enhanced and undesired leakage of hydrophilic actives is prevented. By contrast, adding an alginate shell to PLGA core can lead to a reduction of the initial release rate, thus extending the release period of hydrophobic actives. Microfluidic fabrication enables the generation of precisely controlled core-shell microspheres with a narrow size distribution, which enables the investigation of the relationship between the release kinetics of these microspheres and their characteristics. The approach of using core-shell particles as delivery vehicles creates new opportunities to customize the release kinetics of active ingredients.     

The Coercion Argument Against Performance-Enhancing Drugs

This paper is a critique of the coercion argument against performance-enhancing drugs (PEDs). According to this argument, lifting the ban on PEDs would undermine the autonomy of athletes by creating a situation where everyone must either use PEDs or not compete at the highest levels of sport. Four problems are raised for this argument and it is concluded that the argument fails. A variation on the coercion argument is also considered and rejected.     

The influence of crank rate on peak oxygen consumption during arm crank ergometry

The aim of this study was to assess the influence of three imposed crank rates on the attainment of peak oxygen consumption ( V O 2peak ) and other physiological responses during incremental arm crank ergometry. Twenty physically active, although non-specifically trained, males volunteered for the study. They completed an exercise protocol using an electrically braked arm ergometer (Lode Angio, Groningen, Netherlands) at crank rates of 60, 70 and 80 rev·min -1 . The order of tests was randomized and they were separated by at least 2 days. Peak V O 2 was significantly higher ( P ? 0.05) at 70 and 80 rev·min -1 than at 60 rev·min -1 . Peak ventilation volume increased as a function of crank rate and was higher ( P ? 0.05) at 80 than at 60 rev·min -1 . Peak heart rate was higher ( P ? 0.05) at 70 and 80 rev·min -1 than at 60 rev·min -1 . Furthermore, 70 and 80 rev·min -1 resulted in an extended test time compared with 60 rev·min -1 . The greater physiological responses observed during the tests at the two faster crank rates might have been the result of a postponement of acute localized neuromuscular fatigue, allowing for more work to be completed. We recommend, therefore, that an imposed crank rate between 70 and 80 rev·min -1 should be used to elicit V O 2peak and other physiological responses in arm crank ergometry.     

Demographic characteristics of elite Kenyan endurance runners

Abstract

Kenyan athletes have dominated international distance running in recent years. Explanations for their success include favourable physiological characteristics, which could include favourable genetic endowment, and advantageous environmental conditions. The aim of this study was to compare the demographic characteristics of elite Kenyan runners with those of the general Kenyan population. Questionnaires, administered to 404 elite Kenyan runners specializing in distances ranging from the 800 m to the marathon and 87 Kenyan controls, obtained information on place of birth, language, and distance and method of travel to school. Athletes were separated into two groups according to athletic success: those who competed in international competition and those who competed in national competition. The athletes differed from controls in regional distribution, language, and distance and method of travel to school; athletes also differed from each other with the exception of method of travel to school. Most national and international athletes came from the Rift Valley province (controls 20%, national athletes 65%, international athletes 81%), belonged to the Kalenjin ethnic group (controls 8%, national athletes 49%, international athletes 76%) and Nandi sub-tribe (controls 5%, national athletes 25%, international athletes 44%), and spoke languages of Nilotic origin (controls 21%, national athletes 60%, international athletes 79%). A higher proportion of all athletes ran to school each day (controls 22%, national athletes 73%, international athletes 81%) and covered greater distances. In conclusion, Kenyan runners are from a distinctive environmental background in terms of geographical distribution, ethnicity and travelled further to school, mostly by running. These findings highlight the importance of environmental and social factors in the success of Kenyan runners.