Extremely High Ferritinemia Associated with Haemophagocytic Lympho Histiocytosis (HLH)

Hyperferritinemia (>10,000 ng/ml) is an important hallmark used as an indicator of infection triggered macrophage activation syndrome leading to hemophagocytic lympho histiocytosis (HLH). Measurement of serum ferritin can be used in diagnosis as well as disease monitoring indicator and prognosis related to HLH, cAPS, sepsis, neoplasm and inflammatory conditions. It is a major contributor to manage critically ill patients as predicting and monitoring indicator. It can be used as acute phase response in conditions of MAS, AOSD, cAPS etc. A case study in our hospital showed extremely high ferritin values along with low hemoglobin, elevated LDH and triglycerides with positive MRSA in sputum culture and macrophage proliferation and hemophagocytosis in the bone marrow examination. Patient showed definite inverse relation with steroid therapy and serum ferritin levels.     

The Influence of University Coursework on Pre-service Middle and High School Teachers’ Experiences with Multicultural Themes

The study explored the influence of university-based teacher education courses on pre-service middle and high school teachers’ experiences with multicultural themes in a secondary science alternative certification program. Eight participants (N = 8), six women and two men, volunteered to be a part of the study that took place over a period of four semesters. Qualitative data was collected, coded and analyzed to make meaning of the participants’ experiences. Data comprised of participants’ reflective journals, personal and group interviews, and classroom observations done in middle school practicum and high school student teaching placements. The findings indicated that while the participants became more familiar with the themes of multicultural education, many did not demonstrate fluency with these themes and struggled with balancing their responsibilities as a science teacher and a culturally competent teacher.     

Associations between blocking,monitoring, and filtering software on the home computer and youth-reported unwanted exposure to sexual material online

ObjectiveTo examine the relationship between the use of preventive software on the home computer and unwanted exposure to sexual material online.MethodsThe Youth Internet Safety Survey-2 was a national, RDD telephone survey conducted in March–June 2005. Eight hundred households (one caregiver and one child between the ages of 10 and 17 years) with home Internet access answered questions pertaining to Internet prevention activities in the household and adolescent behaviors and exposures online.ResultsUnwanted exposure to sexual material occurred in 32% of youth in homes with pop-up/spam blockers and 25% of youth in homes with filtering, blocking, or monitoring software on the home computer, compared to 43% of households without preventive software installed on the home computer. Among otherwise similar youth, pop-up/spam blockers installed on the home computer were significantly associated with 59% lower odds of reporting unwanted exposure to sexual material on the home computer; and filtering, blocking, or monitoring software was significantly associated with 65% lower odds. When data were stratified by youth sex, associations between preventive software and unwanted exposure were similar for boys and girls. When stratified by age, preventive software was associated with significantly reduced risk of unwanted exposure for 10–12-year olds and 13–15-year olds, but not for 16–17-year olds.ConclusionAlthough these correlational analyses are far from providing conclusive evidence that preventive software protects children from unwanted exposure to sexual material online, findings suggest that caregivers of boys and girls 15 years of age and younger who want to reduce the likelihood of unwanted exposure to sexual material on the home computer should consider including preventive software—especially filtering, blocking, or monitoring software—in their Internet safety plan.Practice implicationsPractitioners should partner with caregivers in developing an Internet safety plan, including proactive caregiver-youth discussions about expected Internet behavior appropriate for their household.     

Impact of short- compared to long-haul international travel on the sleep and wellbeing of national wheelchair basketball athletes

Currently, very little is known about the impact of short- or long-haul air travel on the sleep and wellbeing of wheelchair basketball athletes. Eleven national wheelchair basketball athletes wore actigraphy monitors prior, during, and after air travel to the United Kingdom. Upon arrival, participants rated their subjective jet-lag, fatigue, and vigor. Individuals traveled to the United Kingdom from different locations in Australia, the United States, and Europe and were categorised according to travel length [LONG (up to 30.2 h) or SHORT (up to 6.5 h)]. Linear mixed models determined effects of travel length on sleep and subjective ratings of jet-lag, fatigue, and vigor. During competition, subjective fatigue and jet-lag were substantially higher (ES = 0.73; ±0.77) and (ES = 0.57; ±0.60), subjective vigor was lower (ES = 1.94; ±0.72), and get-up time was earlier (ES = 0.57; ±0.60) for LONG when compared to SHORT. Travelling greater distances by airplane had a larger effect on subjective ratings of jet-lag, fatigue and vigor, rather than sleep. Irrespective of travel group, sleep and subjective responses were compromised, reflecting the travel requirements, competition-mediated influences, and/or due to a change in environment.     

Methodology and cohort profile for the Hangzhou Lumbar Spine Study: a study focusing on back health in a Chinese population

Back pain is a worldwide health problem, adding a tremendous burden to modern societies. However, little information on back health is available in China, even though a quarter of the world’s population is Chinese. To enhance knowledge in this area, we designed and initiated the Hangzhou Lumbar Spine Study, which is a cross-sectional study of a general sample of mainland Chinese with focusing on disc degeneration, Modic changes, endplate lesions, and back pain. The study consists of a structured questionnaire to measure back pain history and lifetime exposure to suspected risk factors, magnetic resonance imaging of the lumbar spine, bone mineral density study of the spine and hip, and DNA sample analysis. Here we briefly introduce the study methodology, report the test-retest reliability of the questionnaire, and describe the cohort profile to date. Since May 2014, 301 randomly selected subjects (male/female, 122/179; mean age, 51.0 years; range, 20–87 years) have been recruited. Tests-retests of the questionnaire, completed by 40 participants, revealed good reliability. To our knowledge, the Hangzhou Lumbar Spine Study is the first population-based epidemiological study conducted to characterize lumbar spinal phenotypes and back pain, their interaction, and their associations with lifetime environmental exposure, in mainland Chinese. Epidemiological information obtained from a reliable questionnaire, magnetic resonance (MR) imaging data, dual energy X-ray absorptiometry (DXA) measurements, and DNA analysis may serve as a valuable reference for future studies on back health, particularly for mainland Chinese.     

Seeing in the Dark: Embodied Cognition in Amateur Astronomy Practice

We add to research on embodied cognition by investigating the observational practices of amateur astronomers. Specifically, we take an interactionist perspective and examine how the body is recruited, moment by moment, as a resource for producing and communicating meaning during field activity. The data corpus is a set of ethnographic video records and field notes on the routines of a community of astronomers, especially small-group interactions during planning, searching for, observing, and confirming sight of a celestial target. Within this space, our analysis highlights how different modalities of embodied action and reasoning (gestures, tool use, gaze, touch, and others) were deployed and coordinated throughout the process of observing a celestial object and how those emerged in the transactions among participants. Our findings rehearse many issues and topics in the contemporary literature (e.g., gesturing for measuring or representationally) but also reveal important, novel forms of embodied action and reasoning in science, technology, engineering, and mathematics practices (e.g., training the eyes in averted vision and inscribing a celestial scene onto one’s hand). More broadly, these findings further affirm the power of interactionist analyses of knowing and learning while also surfacing areas in which expanded theorizing is needed to account for the full set of cognitive phenomena we observed.     

A Nomogram for the Estimate of Percent Body Fat from Generalized Equations

Abstract

Fifteen well-conditioned college women, who had been thoroughly trained in the correct technique for women's push-ups, were tested for maximal pushing strength in two positions and for the number of complete push-ups they were able to perform at the rate of 41 push-ups per minute. For statistical purposes, calculations of maximal strength for each individual were based upon the average of the recorded maximal arm strengths in the high and low positions plus the average of the weight supported in the high and low positions. The work load was calculated from the distance between the high and low positions, the average supported weight, and the number of push-ups the subject was able to perform until exhausted. A correlation coefficient of .76 was obtained between the calculated maximal strength measures and the work load, indicating a statistically significant positive relationship.     

Effect of ensemble classifier composition on offline cursive character recognition

In this paper we present novel ensemble classifier architectures and investigate their influence for offline cursive character recognition. Cursive characters are represented by feature sets that portray different aspects of character images for recognition purposes. The recognition accuracy can be improved by training ensemble of classifiers on the feature sets. Given the feature sets and the base classifiers, we have developed multiple ensemble classifier compositions under four architectures. The first three architectures are based on the use of multiple feature sets whereas the fourth architecture is based on the use of a unique feature set. Type-1 architecture is composed of homogeneous base classifiers and Type-2 architecture is constructed using heterogeneous base classifiers. Type-3 architecture is based on hierarchical fusion of decisions. In Type-4 architecture a unique feature set is learned by a set of homogeneous base classifiers with different learning parameters. The experimental results demonstrate that the recognition accuracy achieved using the proposed ensemble classifier (with best composition of base classifiers and feature sets) is better than the existing recognition accuracies for offline cursive character recognition.     

Change in Teacher Education: interpreting and experiencing new professional roles

In this paper we consider the effect of moves by the British Government to make initial teacher education (ITE) in England and Wales more school‐based (Blake, 1993). To monitor the impact of this shift towards school‐based training we conducted a fine grain study of what was happening on the ground within the one‐year Secondary School‐Based Postgraduate Certificate in Education (PGCE) at the Chichester Institute of Higher Education (ChIHE). * *At the time the research was conducted, the Institute's name was the West Sussex Institute of Higher Education, hence interviewees refer to ‘WSIHE’ and ‘West Sussex’. View all notes Data were gathered from questionnaire surveys and interviews. Findings from our regional case study indicate that while school‐based ITE programmes may offer student teachers greater insight into school life, this should not be at the expense of developing students’ analytical and theoretical understanding of education and schooling promoted within higher education‐based work.