Robust fluidic connections to freestanding microfluidic hydrogels

Biomimetic scaffolds approaching physiological scale, whose size and large cellular load far exceed the limits of diffusion, require incorporation of a fluidic means to achieve adequate nutrient/metabolite exchange. This need has driven the extension of microfluidic technologies into the area of biomaterials. While construction of perfusable scaffolds is essentially a problem of microfluidic device fabrication, functional implementation of free-standing, thick-tissue constructs depends upon successful integration of external pumping mechanisms through optimized connective assemblies. However, a critical analysis to identify optimal materials/assembly components for hydrogel substrates has received little focus to date. This investigation addresses this issue directly by evaluating the efficacy of a range of adhesive and mechanical fluidic connection methods to gelatin hydrogel constructs based upon both mechanical property analysis and cell compatibility. Results identify a novel bioadhesive, comprised of two enzymatically modified gelatin compounds, for connecting tubing to hydrogel constructs that is both structurally robust and non-cytotoxic. Furthermore, outcomes from this study provide clear evidence that fluidic interconnect success varies with substrate composition (specifically hydrogel versus polydimethylsiloxane), highlighting not only the importance of selecting the appropriately tailored components for fluidic hydrogel systems but also that of encouraging ongoing, targeted exploration of this issue. The optimization of such interconnect systems will ultimately promote exciting scientific and therapeutic developments provided by microfluidic, cell-laden scaffolds.     

Not Quite Free? Irish Postcoloniality and the Career of Pat O'Callaghan

This paper explores the career of the Irish Olympian Pat O'Callaghan. He won successive hammer-throwing titles in the 1924 and 1928 Olympics as a representative of the independent Irish state. The paper argues that in these Olympics, O'Callaghan can be considered as representing a postcolonial state, in line with much scholarship on other aspects of Irish culture. However, the Irish later fell into a dispute with the International Amateur Athletics Federation and the International Olympic Committee, which were largely steered by the British in dealing with contentious issues over the Irish border, and the Irish were thus effectively banned from the 1936 games. The paper concludes with a discussion over the nature of postcolonial identities in sport, and the complexities around the issue in relation to the constant mediation over what national identities mean within the context of rule-making by international sporting bodies.     

The Visual in Sport History: Approaches,Methodologies and Sources

Historians of sport now increasingly accept that visual inquiry offers another dimension to social and cultural research into sport and its history. It is complex and its boundaries are rapidly evolving. This overview offers a justification for placing more emphasis on visual approaches and an introduction to the study and interpretation of visual culture in relation to the history of sport. It stresses the importance of adopting a critical approach and the need to be reflective about that critique. An ever-widening range of visual data are now being explored; so, this paper begins with a brief survey of sources that potentially offer rich returns, from film and photographs to posters and paintings or standards and statues. It next provides a critical assessment at an introductory level of some of the more important methodologies now emerging to help interpret these. This can be no more than a personal choice, given their sheer variety and interdisciplinary nature, and the reality that many historians of sport adopt a mixture of methods and approaches. Approaches covered include content analysis, iconography and iconology, semiology, psychoanalysis, discourse analysis, and reception and audience studies. Examples of recent studies of visual studies are used to illustrate the discussion.     

The Effects of Parental Behavior on Infants' Neural Processing of Emotion Expressions

Infants become sensitive to emotion expressions early in the 1st year and such sensitivity is likely crucial for social development and adaptation. Social interactions with primary caregivers may play a key role in the development of this complex ability. This study aimed to investigate how variations in parenting behavior affect infants' neural responses to emotional faces. Event‐related potentials (ERPs) to emotional faces were recorded from 40 healthy 7‐month‐old infants (24 males). Parental behavior was assessed and coded using the Emotional Availability Scales during free‐play interaction. Sensitive parenting was associated with increased amplitudes to positive facial expressions on the face‐sensitive ERP component, the negative central. Findings are discussed in relation to the interactive mechanisms influencing how infants neurally encode positive emotions.     

Reviewing the Family Unit as a Stakeholder in Talent Development: Is It Undervalued?

As elite youth sport becomes more organized and professionalized, the role of the family is increasingly acknowledged as being significant in the development of young talent. High-profile examples across a range of professional sports, both positive and negative, have drawn attention toward this important stakeholder. Accordingly, this review first examines the key issues in relation to family involvement in talent development in relation to what is perceived as good and bad practice on behalf of the family. Next the key theoretical underpinning is considered, Family Systems Theory, and how it may be integrated within elite youth sport. Finally, the article concludes with a summary of where the current literature leaves us and where we can progress from here. Two possible inputs are suggested that could benefit the effectiveness of family involvement: a focus on the family holistically and a second on the role different family members can play.