Grappling with ‘Natural Selection’ — Experiences of a Teacher

Since evolution forms the core of modern biology, teaching about natural selection is extremely important as this equips the student to frame the ‘why’ questions properly and, at the same time, sharpens their understanding about a host of issues pertaining to behaviour, diversity and genetics.     

课前指导与补充指导对学生网络学习的影响

马来西亚开放大学（OUM）90％以上的学生为在职人员。这些成年学生离开学校至少已经5年,而且大多数人的数学基础不好。因此,仅是在线学习加少量面授辅导的教学模式对他们来说还不能完全解决学习困难。学校试用了“课前指导工作室”与“补充指导”的教学方法,探讨了这一方法对学员的在线参与程度及考试结果的影响,运用源于探究团体模式的34项量表对在线论坛的内容进行了分析,结果表明,学员参加工作室与否同他们的期末考试成绩有很大关系。参加指导老师工作室及补充指导的学员与那些参加指导老师常规指导的学员相比,前者的在线参与程度及期末考试的平均分都存在着很大的差异。两组学员的数学探究团体模式平均分表明,两组学员在教学存在和认知存在方面有差异,但在社会存在方面基本相同。     

Application of automated image analysis to the identification and extraction of recyclable plastic bottles

An experimental machine vision apparatus was used to identify and extract recyclable plastic bottles out of a conveyor belt. Color images were taken with a commercially available Webcam, and the recognition was performed by our homemade software, based on the shape and dimensions of object images. The software was able to manage multiple bottles in a single image and was additionally extended to cases involving touching bottles. The identification was fulfilled by comparing the set of measured features with an existing database and meanwhile integrating various recognition techniques such as minimum distance in the feature space, self-organized maps, and neural networks. The recognition system was tested on a set of 50 different bottles and provided so far an accuracy of about 97% on bottle identification. The extraction of the bottles was performed by means of a pneumatic arm, which was activated according to the plastic type; polyethylene-terephthalate （PET） bottles were left on the conveyor belt, while non-PET bottles were extracted. The software was designed to provide the best compromise between reliability and speed for real-time applications in view of the commercialization of the system at existing recycling plants.     

Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats

Chlorella vulgaris (CV) has been reported to have antioxidant and anticancer properties. We evaluated the effect of CV on apoptotic regulator protein expression in liver cancer-induced rats. Male Wistar rats (200∼250 g) were divided into eight groups: control group (normal diet), CDE group (choline deficient diet supplemented with ethionine in drinking water to induce hepatocarcinogenesis), CV groups with three different doses of CV (50, 150, and 300 mg/kg body weight), and CDE groups treated with different doses of CV (50, 150, and 300 mg/kg body weight). Rats were sacrificed at various weeks and liver tissues were embedded in paraffin blocks for immunohistochemistry studies. CV, at increasing doses, decreased the expression of anti-apoptotic protein, Bcl-2, but increased the expression of pro-apoptotic protein, caspase 8, in CDE rats, which was correlated with decreased hepatoctyes proliferation and increased apoptosis as determined by bromodeoxy-uridine (BrdU) labeling and terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling (TUNEL) assay, respectively. Our study shows that CV has definite chemopreventive effect by inducing apoptosis via decreasing the expression of Bcl-2 and increasing the expression of caspase 8 in hepatocarcinogenesis-induced rats. Project supported by Department of Biochemistry, Faculty of Medicine, UKM Medical Center, Universiti Kebangsaan Malaysia, and the Malaysian Ministry of Science and Technological Innovation (MOSTI)     

建立知识社会

人类社会正经历着向知识社会的转变;知识正日益成为经济发展和社会进步的核心因素.身处全球迈向知识社会的进程之中,我们目睹和亲历着世界性的合作、竞争、流动和创新.技术变革无疑是这一进程的强大驱动力之一;而在技术不断取得极大进步,知识与信息以空前的数量产生和极快的速度传播的同时,也存在着知识鸿沟或数字鸿沟现象.     

The inculcation of generic skills among juveniles through Technical and Vocational Education

Generic skills are skills which contribute towards individual＇s effective and successful participation in the workplace. For juveniles, Technical and Vocational Education （TVE） is one of the platforms that provide them generic skills which enable them to compete for job market. The purpose of this study is to investigate the level of generic skills that has been inculcated through TVE on juveniles in one of the juvenile schools in Malaysia, the time the teachers spent on inculcating the skills, and the challenges the instructors face in the process. There are four focuses of the generic skills that are of interest in this study： communication, teamwork, problem solving and technology. Eight teachers and 119 juveniles were chosen as the respondents from the Juvenile School （JS）. The data collected was through a set of questionnaires from the respondents, and these were analyzed by using frequency, percentage and mean score. The findings from this research show that the level of generic skills inculcated as perceived by the juveniles is at a moderate level. The perceived moderate level of skill acquire of the juveniles is justified by the moderate amount of time that the teachers believed they spend in instilling the generic skills. The teachers also suggested that the lack of understanding on what generic skills are is the main reason for not inculcating generic skills at its highest level. In conclusion, generic skills inculcation on juveniles through TVE in Juvenile School is at an average level. Measures have to be taken so that inculcation of generic skills can be increase to a higher level, as these generic skills will benefit juveniles in the labor force market.     

Using cloud computing services in e-learning process: Benefits and challenges

During the recent years, Information and Communication Technologies (ICT) play a significant role in the field of education and e-learning has become a very popular trend of the education technology. However, with the huge growth of the number of users, data and educational resources generated, e-learning systems have become more and more expansive in terms of hardware and software resources, and many educational institutions cannot afford such ICT investments. Due to its tremendous advantages, cloud computing technology rises swiftly as a natural platform to provide support to e-learning systems. This paper focuses on the research on the application of cloud computing in e-learning. The aim of this paper is to give an overview of the current state and the impact of the use of cloud computing for e-learning. Thus, at first the paper introduces concepts of e-learning and cloud computing infrastructure with their key characteristics. The paper analyzes also challenges facing e-learning systems deployment. In follow the paper considers cloud-based e-learning solutions by focusing on the raisons of the convenience of cloud computing for e-learning. Therefore cloud computing benefits are introduced as a solution for these challenges. Finally, the paper presents some solutions of cloud computing in e-learning and describes the most common architecture adopted. Issues in implementing cloud-based e-learning systems and some potential ways to overcome them are also discussed.     

Transforming Growth Factor-β1/Smad3 Signaling and Redox Status in Experimentally Induced Nephrotoxicity: Impact of Carnosine

Exposure to various organic compounds including drugs and environmental toxins causes cellular damage through generation of free radicals. Carnosine a dipeptide was used in this study to evaluate its effect against CCl4-induced nephrotoxicity. Sixty male albino rats were involved in this study and were equally divided into four groups. CCl4 (3 ml/kg body weight; biweekly for 4 weeks) was given to group II and III. Carnosine (10 mg/kg body weight; once daily for 4 weeks) was given to group III and VI. Transforming growth factor-β1 (TGF-β1) level by immunoassay and Smad3 mRNA level by real-time PCR were estimated in addition to cytochrome P450 2E1 (CYP2E1) activity, renal functions, redox status assessment and histopathological examination of the kidney. Carnosine significantly improved kidney function, renal redox status, decreased renal CYP2E1 activity, TGF-β1 level and Smad3 gene expression when compared to CCL4-intoxicated group. The protective effect of carnosine was confirmed by histopathological study. In conclusion: carnosine has the ability to protect against CCl4-induced nephrotoxicity possibly by alleviating oxidative stress, normalizing kidney histopathological architecture in addition to the disruption of the inflammatory and fibrotic response induced by CCl4.     

Knowledge heterogeneity and social network analysis – Towards conceptual and measurement clarifications

This literature review highlights some Social Network Analysis (SNA) concepts applicable to the study of organizational knowledge and, more particularly, to knowledge heterogeneity. Knowledge being all at the same time decentralized and distributed, knowing up to what point knowledge can be heterogeneous or homogeneous across organizational units becomes as important as the question of knowing how to structure the organization. SNA applied to knowledge management thus seems a stimulant for future research in the fields of management.