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11.
Real options analysis was often recommended as an emerging valuation technique for high-risk investment projects. Former inter-sectoral surveys have drawn an ambivalent picture of real options usage in general. In addition, there is a lack of sector-specific investigations. In the following article the results of an in-depth analysis of collected empirical data regarding the application of this new tool in the pharmaceutical sector is presented by capturing the internal view from the pharmaceutical companies themselves and the external view from the health care departments of financial service firms. R&D stage specific modi of application, reasons for reluctance in the employment of real options and their assumed future prospects are elucidated. 相似文献
12.
Salam Maimoona Awang Iskandar Dayang Nurfatimah Ibrahim Dayang Hanani Abang Farooq Muhammad Shoaib 《Asia Pacific Education Review》2019,20(4):573-593
Asia Pacific Education Review - In the last few years, adoption of service learning in higher educational institutions has emerged as a modern teaching and learning strategy. This study is aimed to... 相似文献
13.
Dong-Dong Wu Cui-Ping Yang Ming-Shan Wang Kun-Zhe Dong Da-Wei Yan Zi-Qian Hao Song-Qing Fan Shu-Zhou Chu Qiu-Shuo Shen Li-Ping Jiang Yan Li Lin Zeng He-Qun Liu Hai-Bing Xie Yun-Fei Ma Xiao-Yan Kong Shu-Li Yang Xin-Xing Dong Ali Esmailizadeh David M Irwin Xiao Xiao Ming Li Yang Dong Wen Wang Peng Shi Hai-Peng Li Yue-Hui Ma Xiao Gou Yong-Bin Chen Ya-Ping Zhang 《国家科学评论(英文版)》2020,7(6):952
Abundant and diverse domestic mammals living on the Tibetan Plateau provide useful materials for investigating adaptive evolution and genetic convergence. Here, we used 327 genomes from horses, sheep, goats, cattle, pigs and dogs living at both high and low altitudes, including 73 genomes generated for this study, to disentangle the genetic mechanisms underlying local adaptation of domestic mammals. Although molecular convergence is comparatively rare at the DNA sequence level, we found convergent signature of positive selection at the gene level, particularly the EPAS1 gene in these Tibetan domestic mammals. We also reported a potential function in response to hypoxia for the gene C10orf67, which underwent positive selection in three of the domestic mammals. Our data provide an insight into adaptive evolution of high-altitude domestic mammals, and should facilitate the search for additional novel genes involved in the hypoxia response pathway. 相似文献
14.
Sajjad Rahmani Dabbagh Fazle Rabbi Zafer Doan Ali Kemal Yetisen Savas Tasoglu 《Biomicrofluidics》2020,14(6)
High-throughput, cost-effective, and portable devices can enhance the performance of point-of-care tests. Such devices are able to acquire images from samples at a high rate in combination with microfluidic chips in point-of-care applications. However, interpreting and analyzing the large amount of acquired data is not only a labor-intensive and time-consuming process, but also prone to the bias of the user and low accuracy. Integrating machine learning (ML) with the image acquisition capability of smartphones as well as increasing computing power could address the need for high-throughput, accurate, and automatized detection, data processing, and quantification of results. Here, ML-supported diagnostic technologies are presented. These technologies include quantification of colorimetric tests, classification of biological samples (cells and sperms), soft sensors, assay type detection, and recognition of the fluid properties. Challenges regarding the implementation of ML methods, including the required number of data points, image acquisition prerequisites, and execution of data-limited experiments are also discussed. 相似文献
15.
Ali Asghar Ghasemi Hooshang Yazdani Majid Amerian 《Journal of Intercultural Communication Research》2020,49(1):41-60
ABSTRACTThis study aimed to present a model of intercultural communicative competence (ICC) by incorporating international posture, motivational disposition (ideal L2 self), second language (L2) self-confidence, and metacognitive learning strategies. To this end, 150 Iranian L2 learners, selected through convenience sampling procedure, took part in the research. The findings of structural equation modelling revealed that the proposed model showed adequate fit to the data, implying that the model is appropriate in Iranian English as a foreign language (EFL) context. Also, the results indicated that learners with a high level of international posture are more likely to bridge the gap between their present and ideal selves. This was, additionally, argued that internationally oriented and ideally motivated learners become confident of their abilities to get engaged in interaction with L2 target communities. Furthermore, metacognitive learning strategies were found to be directly associated with ICC, implicating that the learners who continuously reflect on their learning and evaluate their performances are more prone to have a higher level of ICC. Finally, suggestions were offered for language teachers and policy-makers to inspire their learners to be more competent in communication with people of other cultures and languages. 相似文献
16.
Robert Dan Michael Cate A. Egan Lynda Nilges Ali Brian Robert Johnson 《Research quarterly for exercise and sport》2019,90(2):151-162
Purpose: A systematic review was conducted to identify facilitators and barriers to movement integration (MI) in elementary school classrooms. Method: Online databases (Educational Resources Information Center, Google Scholar, PsycINFO, and PubMed) served as data sources for the study. Following the PRISMA guidelines, relevant published research on MI was identified and screened for inclusion in a qualitative synthesis. Content analysis of the included articles (N = 28) was used to identify themes of MI facilitators and barriers. Facilitators and barriers were then categorized using a social-ecological framework. Results: A total of 12 themes of MI facilitators and barriers were identified and categorized into two social-ecological levels: institutional factors (e.g., administrative support, resources) and intrapersonal factors (e.g., teacher confidence, ease of implementation). Conclusion: This review can inform research and practice aimed at supporting the implementation of MI in elementary classrooms. 相似文献
17.
Personal Review: Sources of sulfide in waste streams and current biotechnologies for its removal 总被引:6,自引:0,他引:6
MAHMOOD Qaisar ZHENG Ping CAI Jing HAYAT Yousaf HASSAN Muhammad Jaffar WU Dong-lei HU Bao-lan 《浙江大学学报(A卷英文版)》2007,8(7):1126-1140
Sulfide-containing waste streams are generated by a number of industries. It is emitted into the environment as dis- solved sulfide (S2- and HS-) in wastewaters and as H2S in waste gases. Due to its corrosive nature, biological hydrogen sulfide removal processes are being investigated to overcome the chemical and disposal costs associated with existing chemically based removal processes. The nitrogen and sulfur metabolism interacts at various levels of the wastewater treatment process. Hence, the sulfur cycle offers possibilities to integrate nitrogen removal in the treatment process, which needs to be further optimized by appropriate design of the reactor configuration, optimization of performance parameters, retention of biomass and optimization of biomass growth. The present paper reviews the biotechnological advances to remove sulfides from various environments. 相似文献
18.
19.
Muhammad Farooq Naseer Manasa Patnam Reehana R. Raza 《Economics of Education Review》2010,29(4):669-683
This paper evaluates the impact of teaching innovations, introduced in public primary schools under the Children Resources International (CRI) Program, on student outcomes. We estimate students’ learning based on their scores on standardized tests. We match schools and children within the treatment and comparison group and find that the CRI Program has been effective in raising learning achievement. Moreover, the results are robust to unobserved selection bias. The average gain for a CRI student represents an improvement of 0.40 standard deviations. The results stay unchanged when we use alternative estimators for the treatment effect including the bias-corrected estimator proposed by Abadie and Imbens (2006). 相似文献
20.
Fatma Emel Kocak Bahadir Ozturk Ozben Ozden Isiklar Ozlem Genc Ali Unlu Irfan Altuntas 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2015,25(3):430-438