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81.
Noëmi Manders-Huits 《Ethics and Information Technology》2010,12(1):1-2
Over the past decade Identity Management has become a central theme in information technology, policy, and administration
in the public and private sectors. In these contexts the term ‘Identity Management’ is used primarily to refer to ways and
methods of dealing with registration and authorization issues regarding persons in organizational and service-oriented domains.
Especially due to the growing range of choices and options for, and the enhanced autonomy and rights of, employees, citizens,
and customers, there is a growing demand for systems that enable the regulation of rights, duties, responsibilities, entitlements
and access of innumerable people simultaneously. ‘Identity Management’ or ‘Identity Management Systems’ have become important
headings under which such systems are designed and implemented. But there is another meaning of the term ‘identity management’,
which is clearly related and which has gained currency. This second construal refers to the need to manage our moral identities
and our identity related information. This paper explores the relation between the management of our (moral) identities and
‘Identity Management’ as conceptualized in IT discourse. 相似文献
82.
Singh PP Chandra A Mahdi F Roy A Sharma P 《Indian journal of clinical biochemistry : IJCB》2010,25(3):225-243
The antioxidants are essential molecules in human system but are not miracle molecules. They are neither performance enhancers
nor can prevent or cure diseases when taken in excess. Their supplemental value is debateable. In fact, many high quality
clinical trials on antioxidant supplement have shown no effect or adverse outcomes ranging from morbidity to all cause mortality.
Several Chochrane Meta-analysis and Markov Model techniques, which are presently best available statistical models to derive
conclusive answers for comparing large number of trials, support these claims. Nevertheless none of these statistical techniques
are flawless. Hence, more efforts are needed to develop perfect statistical model to analyze the pooled data and further double
blind, placebo controlled interventional clinical trials, which are gold standard, should be implicitly conducted to get explicit
answers. Superoxide dismutase (SOD), glutathione peroxidase and catalase are termed as primary antioxidants as these scavenge
superoxide anion and hydrogen peroxide. All these three enzymes are inducible enzymes, thereby inherently meaning that body
increases or decreases their activity as per requirement. Hence there is no need to attempt to manipulate their activity nor
have such efforts been clinically useful. SOD administration has been tried in some conditions especially in cancer and myocardial
infarction but has largely failed, probably because SOD is a large molecule and can not cross cell membrane. The dietary antioxidants,
including nutrient antioxidants are chain breaking antioxidants and in tandem with enzyme antioxidants temper the reactive
oxygen species (ROS) and reactive nitrogen species (RNS) within physiological limits. Since body is able to regulate its own
requirements of enzyme antioxidants, the diet must provide adequate quantity of non-enzymic antioxidants to meet the normal
requirements and provide protection in exigent condition. So far, there is no evidence that human tissues ever experience
the torrent of reactive species and that in chronic conditions with mildly enhanced generation of reactive species, the body
can meet them squarely if antioxidants defense system in tissues is biochemically optimized. We are not yet certain about
optimal levels of antioxidants in tissues. Two ways have been used to assess them: first by dietary intake and second by measuring
plasma levels. Lately determination of plasma/serum level of antioxidants is considered better index for diagnostic and prognostic
purposes. The recommended levels for vitamin A, E and C and beta carotene are 2.2–2.8 μmol/l; 27.5–30 μmol/l; 40–50 μmol/l
and 0.4–0.5 μmol/l, respectively. The requirement and recommended blood levels of other dietary antioxidants are not established.
The resolved issues are (1) essential to scavenge excess of radical species (2) participants in redox homeostasis (3) selective
antioxidants activity against radical species (4) there is no universal antioxidant and 5) therapeutic value in case of deficiency.
The overarching issues are (1) therapeutic value as adjuvant therapy in management of diseases (2) supplemental value in developing
population (3) selective interactivity of antioxidant in different tissues and on different substrates (4) quantitative contribution
in redox balance (5) mechanisms of adverse action on excess supplementation (6) advantages and disadvantages of prooxidant
behavior of antioxidants (7) behavior in cohorts with polymorphic differences (8) interaction and intervention in radiotherapy,
diabetes and diabetic complications and cardiovascular diseases (9) preventive behavior in neurological disorders (10) benefits
of non-nutrient dietary antioxidants (11) markers to assess optimized antioxidants status (12) assessment of benefits of supplementation
in alcoholics and heavy smokers. The unresolved and intriguing issues are (1) many compounds such as vitamin A and many others
possessing both antioxidant and non-antioxidant properties contribute to both the activities in vivo or exclusively only to
non-antioxidant activity and (2) since human tissues do not experience the surge of FR, whether there is any need to develop
stronger synthetic antioxidants. Theoretically such antioxidants may do more harm than good. 相似文献
83.
Ritu Sharma Mridula Mahajan Ravi Kant 《Indian journal of clinical biochemistry : IJCB》2004,19(1):10-13
Serum total lipids (cholesterol and triglyceride), lipoproteins (VLDL, LDL and HDL) and Apolipoprotein-B levels of normal
healthy individuals (n=25) and coronary artery disease patients (n=25) were estimated. The objective of the present study
was to ascertain the role of apo-B in causation and inheritance of coronary artery disease. It was observed that on an average
serum total cholesterol and triglyceride more than 200 mg/dl bring the individuals to a risk of coronary artery disease (CAD)
irrespective of the age. CAD patients achieved this value at an early age (35–45 years). Similarly VLDL and LDL levels were
found to be significantly raised in CAD patients when compared to that of age matched normal individuals, with patients achieving
risk values at an early age. HDL levels were found to be significantly lower in CAD patients as compared to normal individuals.
Serum apo-B levels were significantly raised in CAD patients as compared to age matched normal individuals. Patients with
positive family history of CAD had raised serum apo-B levels than those having negative family history. A positive coefficient
of correlation was observed between serum apo-B and LDL levels suggesting that more the number of Apo-B particles, more will
be the synthesis of atherogenic particle (LDL). Patients with negative family history had serum apo-B levels closer to those
of normal individuals and in these individuals HDL levels were found to be significantly lowered, suggesting that loss of
scavenger role of HDL could be the risk factor responsible for the causation of CAD in these patients, with negative family
history of coronary artery disease. 相似文献
84.
Miriam Delgado-Verde Javier Amores-Salvadó Gregorio Martín-de Castro José Emilio Navas-López 《知识管理研究与实践》2014,12(3):261-275
Although the importance of intellectual capital has already been highlighted in the management literature, few articles have focused on the importance of its green counterpart, green intellectual capital. Nowadays, when environmental concerns cannot be ignored by firms, it is therefore time to explore the role of green intellectual capital in environmental improvement. For that reason, our research aims to explore the relationships between green intellectual capital components and the environmental performance of the firms. In particular, we try to show the importance of green organizational and social capital in the development of environmental product innovations, which are vital to the development and implementation of environmental strategies since, as scholars have pointed out, they generate some of the greatest environmental impacts. The empirical results show that green organizational capital has an indirect impact on environmental product innovation through green social capital, meaning that the latter is a significant mediator of that relationship, and at the same time emphasizing that informal relationships play a key role in the improvement of the environmental performance of the firm and, more specifically, in the development of environmental product innovations. 相似文献
85.
This study aims to examine the relationships between managerial learning as a facet of knowledge absorption (KA), firm innovation as a facet of knowledge exploitation (KE), and performance of small firms (i.e., firms with fewer than 50 employees). It builds on the knowledge-based view of the firm and the upper echelons theory to describe the effects of KA on KE, and that of KE on firm performance, in the small-firm context. Using survey data of 1441 small firms in New Zealand, the study applies a partial least squares approach to structural equation modelling to test the main hypotheses of the study. The main findings show the positive and significant effects of three types of managerial learning, namely, practice-based, proximal, and distal learning, on innovation and on innovation in firm performance. However, the curvilinear relationships suggest rather that the effects are finite and, potentially, confounded by factors unaccounted for in the models. 相似文献
86.
Kristina Andersson 《Cultural Studies of Science Education》2017,12(2):425-433
Marie Ståhl and Anita Hussénius have defined what discourses dominate national tests in chemistry for Grade 9 in Sweden by using feminist, critical didactic perspectives. This response seeks to expand the results in Ståhl and Hussénius’s article Chemistry inside an epistemological community box!—Discursive exclusions and inclusions in the Swedish national tests in chemistry, by using different facets of gender awareness. The first facet—Gender awareness in relations to the test designers’ own conceptions—highlighted how the gender order where women are subordinated men becomes visible in the national tests as a consequence of the test designers internalized conceptions. The second facet—Gender awareness in relation to chemistry—discussed the hierarchy between discourses within chemistry. The third facet—Gender awareness in relation to students—problematized chemistry in relation to the students’ identity formation. In summary, I suggest that the different discourses can open up new ways to interpret chemistry and perhaps dismantle the hegemonic chemistry discourse. 相似文献
87.
88.
Recently direct optimization of information retrieval (IR) measures has become a new trend in learning to rank. In this paper,
we propose a general framework for direct optimization of IR measures, which enjoys several theoretical advantages. The general
framework, which can be used to optimize most IR measures, addresses the task by approximating the IR measures and optimizing
the approximated surrogate functions. Theoretical analysis shows that a high approximation accuracy can be achieved by the
framework. We take average precision (AP) and normalized discounted cumulated gains (NDCG) as examples to demonstrate how
to realize the proposed framework. Experiments on benchmark datasets show that the algorithms deduced from our framework are
very effective when compared to existing methods. The empirical results also agree well with the theoretical results obtained
in the paper. 相似文献
89.
A novel floating foundation to support the NREL offshore 5 MW wind turbine was designed conceptually by combining the characteristics of barge and Spar. The main focus was structural design and hydrodynamic modelling. Based on this novel floating foundation, the hydrodynamic performance was investigated in the frequency domain and time domain by using the wave analysis software HydroD and DeepC from Det Norske Veritas. The frequency domain analysis was conducted to investigate the effects of the incident wave angle and water depth. The time-domain analysis was carried out to evaluate the response of the floating foundation under a selected operational condition. The hydrodynamic performances of this floating foundation with respect to time series and response spectra were also investigated in this study. 相似文献
90.
ZHANG Ji-gao 《浙江大学学报(A卷英文版)》2007,8(3):361-369
Particle pollution in air, also sometimes known as fine dust contamination, may cause electric contact failure. Recent research further proved that the fine particle is becoming a major disruption of the electronic connectors in signal transmission system. This paper specifies the connector contact in mobile phone application. To study the contact failure of mobile phone, a series of inspections and analytical research methods are introduced. Special features that cause the contact failure are summarized. Particle accumulation is the main problem; organic material such as lactates from sweat of the human body may act as adhesives to stick the separate particles together and make them adhere on the contact surface; chemical properties of dust cause serious local corrosion. The corrosion products may trap the particles and firmly attach on the contact surface; micro motion frequently occurs at the contact interface. Hard particle can be embedded into the surface, and soft particle could be squeezed and inserted into the contact; silicon compounds in dust play the most important role in forming high resistance regions that lead to failure; deposition of particles depends on the amount of materials, static electricity attracting force and gravity force applied on the particles. Current dust test can hardly reflect the serious contact failure. It is difficult to simulate the complexity of contact failure caused by particle contamination. Thus alternative ways of simulation experiment and improvement of contact reliability are proposed. 相似文献