Microfluidic device for trapping and monitoring three dimensional multicell spheroids using electrical impedance spectroscopy

In this paper, we report the design, fabrication, and testing of a lab-on-a-chip based microfluidic device for application of trapping and measuring the dielectric properties of microtumors over time using electrical impedance spectroscopy (EIS). Microelectromechanical system (MEMS) techniques were used to embed opposing electrodes onto the top and bottom surfaces of a microfluidic channel fabricated using Pyrex substrate, chrome gold, SU-8, and polydimethylsiloxane. Differing concentrations of cell culture medium, differing sized polystyrene beads, and MCF-7 microtumor spheroids were used to validate the designs ability to detect background conductivity changes and dielectric particle diameter changes between electrodes. The observed changes in cell medium concentrations demonstrated a linear relation to extracted solution resistance (Rs), while polystyrene beads and multicell spheroids induced changes in magnitude consistent with diameter increase. This design permits optical correlation between electrical measurements and EIS spectra.     

A group recommender for movies based on content similarity and popularity

People are gregarious by nature, which explains why group activities, from colleagues sharing a meal to friends attending a book club event together, are the social norm. Online group recommenders identify items of interest, such as restaurants, movies, and books, that satisfy the collective needs of a group (rather than the interests of individual group members). With a number of new movies being released every week, online recommenders play a significant role in suggesting movies for family members or groups of friends/people to watch, either at home or at movie theaters. Making group recommendations relevant to the joint interests of a group, however, is not a trivial task due to the diversity in preferences among group members. To address this issue, we introduce GroupReM which makes movie recommendations appealing (to a certain degree) to members of a group by (i) employing a merging strategy to explore individual group members’ interests in movies and create a profile that reflects the preferences of the group on movies, (ii) using word-correlation factors to find movies similar in content, and (iii) considering the popularity of movies at a movie website. Unlike existing group recommenders based on collaborative filtering (CF) which consider ratings of movies to perform the recommendation task, GroupReM primarily employs (personal) tags for capturing the contents of movies considered for recommendation and group members’ interests. The design of GroupReM, which is simple and domain-independent, can easily be extended to make group recommendations on items other than movies. Empirical studies conducted using more than 3000 groups of different users in the MovieLens dataset, which are various in terms of numbers and preferences in movies, show that GroupReM is highly effective and efficient in recommending movies appealing to a group. Experimental results also verify that GroupReM outperforms popular CF-based recommenders in making group recommendations.     

Relationships between writing motives,writing self-efficacy and time on writing among Chinese students: path models and cluster analyses

Reading and Writing - Motives for writing is a new research area in the field of writing motivation. Recent studies have identified important motives for students’ writing. Adding to this...     

Counselor educators using self as instrument in antiracist teaching

In this autoethnography inquiry, seven counselor educators from diverse intersectionalities discuss how they leverage their selfhood to promote antiracist counselor education. Based on two cycles of pattern coding, the authors identified themes of perceiving, experiencing, creating, and facilitating. Implications for future research and practice are offered.     

Real-time measurement of thrombin generation using continuous droplet microfluidics

Thrombin, which has the leading role in the blood coagulation cascade, is an important biomarker in hemostasis and cardiovascular disease (CVD) development. In this study, a measurement system capable of continuously monitoring individual thrombin generation using droplet microfluidic technology is manipulated. The thrombin generation assay based on fluogenic substrate is performed within the droplets and the thrombin generation curve of plasma sample activated by tissue factor is measured in real-time to reflect the sample conditions dynamically. The injection of the inhibitor of thrombin generation is developed to assay the inhibited curve which relates to thrombin self-inhibition in biological systems. This microfluidic system is integrated with the microdialysis probe, which is useful to connect to the living animals for future in vivo real time thrombin measurements for rapid CVD diagnosis.     

Why Are Chinese Mothers More Controlling Than American Mothers? “My Child Is My Report Card”

Chinese parents exert more control over children than do American parents. The current research examined whether this is due in part to Chinese parents' feelings of worth being more contingent on children's performance. Twice over a year, 215 mothers and children (M_age = 12.86 years) in China and the United States (European and African American) reported on psychologically controlling parenting. Mothers also indicated the extent to which their worth is contingent on children's performance. Psychologically controlling parenting was higher among Chinese than American mothers, particularly European (vs. African) American mothers. Chinese (vs. American) mothers' feelings of worth were more contingent on children's performance, with this contributing to their heightened psychological control relative to American mothers.     

Articulation of medium of instruction politics in the Malaysian Chinese press

In postcolonial multilingual societies, matters of education are deeply rooted in the discourse of ethnicity. In Malaysia, the interface between ethnicity and education is reflected in recent debates on the choice of medium of instruction (MOI). In 2002, the Malaysian government introduced English as MOI by replacing Malay, the national language, for teaching mathematics and science, at the school level. However, in 2009, the policy was reversed to Malay. This policy initiative has been actively contested in the Malaysian media. Through an analysis of news reports on the controversy published by the Malaysian Chinese newspaper, Nanyang Siang Pao, this paper aims to illustrate how a sizeable ethnic minority is able to position itself vis-à-vis a national policy. To explain the ethno-political construction of MOI debates in the newspaper, we use two concepts, namely, ‘plurality of struggles’ (Laclau, 2006a, 2006b; Laclau & Mouffe, 1985) and ‘transmission of the speech of others’ (Bakhtin, 1981). These notions are contextualized in the macro-context of a multi-ethnic polity in which Chinese society, Chinese press and Chinese education are seen to co-construct community interests.     

Conceptualizing the Counseling Training Environment Using Bronfenbrenner’s Ecological Theory

While learning environment research has been growing in popularity over the past few decades, little attention has been given towards the learning environment of graduate students, and virtually no attention has been given specifically towards graduate counseling and related programs such as professional counseling, clinical and counseling psychology, and marriage and family therapy. In this paper we propose using Bronfenbrenner’s (1979, 1992) ecological theory as a model to conceptualize the training environment of such counselor preparation programs. Through the application of Bronfenbrenner’s theory, counselor educators and counseling trainees can better understand the systemic nature of the training environment that they create and where they train. Implications and recommendations for future research are provided to further advance the knowledge and awareness of the counseling training environment.