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471.
Much research into the use of corpora and discourse to support higher education students on pre-sessional and in-sessional courses champions subject specificity. Drawing on the work of writers such as Bakhtin [(1981). The dialogic imagination: Four essays by MM Bakhtin (M. Holquist, Ed.; C. Emerson & M. Holquist, Trans.). Austin: University of Texas Press] and Voloshinov [(1973). Marxism and the philosophy of language (L. Matejka, & I.R. Titunik, Trans.). New York: Seminar Press. (Original work published 1929)], in this article we extend this research by showing how the specific subject ‘context’ is fundamentally linked with the ‘English’ used within it. We first detail some of the literature related to corpus and genre studies and discuss some of the literature related to the importance of providing a context for language. We then present and discuss data from 21 interviews and five focus groups with subject lecturers to illustrate how the ‘English’ used in the subject areas of ‘Design’, ‘Nursing’, ‘Business’ and ‘Computing’ subjects flows through what we term their ‘paradigmatic hearts’. By ‘paradigmatic heart’ we mean the set of values, beliefs and perceptions that represent the central or innermost engine of the subject, through which its ‘English’ flows. In ‘Design’ the paradigmatic heart is ‘visual’, ‘philosophical’ and ‘persuasive’; for ‘Nursing’ it is ‘emotional’ and ‘empathetic’, yet also ‘technical’; for ‘Business’ subjects it is ‘income generating’, ‘numerical’ and ‘persuasive’; and for ‘Computing’ it may be ‘visual’, ‘numerical’ or ‘code-based’. We demonstrate how ‘English’ flows through the paradigmatic heart of its subject and that to remove the ‘English’ from its subject paradigmatic heart changes its nature. Thus, we argue that if students are not being taught ‘English’ in the context of the subject, the ‘English’ we are teaching them will be different, and that preparation and support needs to be undertaken in the subject itself.  相似文献   
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Intestinal enteroids are ex vivo primary cultured single-layer epithelial cell spheroids of average diameter ∼150 μm with luminal surface facing inward. Measurement of enteroid swelling in response to secretagogues has been applied to genetic testing in cystic fibrosis and evaluation of drug candidates for cystic fibrosis and secretory diarrheas. The current measurement method involves manual addition of drugs and solutions to enteroids embedded in a Matrigel matrix and estimation of volume changes from confocal images of fluorescently stained enteroids. We developed a microfluidics platform for efficient trapping and immobilization of enteroids for quantitative measurement of volume changes. Multiple enteroids are trapped in a “pinball machine-like” array of polydimethylsiloxane posts for measurement of volume changes in unlabeled enteroids by imaging of an extracellular, high-molecular weight fluorescent dye. Measurement accuracy was validated using slowly expanding air bubbles. The method was applied to measure swelling of mouse jejunal enteroids in response to an osmotic challenge and cholera toxin-induced chloride secretion. The microfluidics platform allows for parallel measurement of volume changes on multiple enteroids during continuous superfusion, without an immobilizing matrix, and for quantitative volume determination without chemical labeling or assumptions about enteroid shape changes during swelling.  相似文献   
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The aim of this study was trying to predict success in the qualifying round for the International Chemistry Olympiad (IChO) on the basis of the expectancy-value model of achievement motivation by Eccles et al. The investigation with 52 participants, including 14 females, was conducted during the third of four qualifying rounds of the IChO in Germany. The subjects filled in a questionnaire, took an intelligence test, and participated in two theoretical chemistry exams. Male and female Olympians showed large differences in parental support, motivation, and emotion as well as test performance. Ultimately, only one female participant qualified for the fourth round of the IChO. The model of Eccles et al. was well suited for predicting test performance in the competition. The strongest predictor was found to be the participation in a previous IChO. The implications for reducing gender differences and promoting scientifically talented students are discussed.  相似文献   
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Abstract

The purpose of this study was to establish if vertical stiffness was greater in professional Australian rules footballers who sustained a lower limb skeletal muscle strain compared to those who did not, and to establish if a relationship between age, or training history, and vertical stiffness existed. Thirty-one participants underwent weekly rebound jump testing on a force platform over two seasons. Vertical stiffness was calculated for injured players and the uninjured cohort 1 and 3 weeks prior to sustaining an injury and at the end of preseason. Eighteen athletes were in the “uninjured” cohort and 13 in the “injured” cohort. No significant difference in vertical stiffness was observed between groups (P = 0.18 for absolute stiffness; P = 0.08 for stiffness relative to body mass), within groups (P = 0.83 and P = 0.88, respectively) or for a time*cohort interaction (P = 0.77 and P = 0.80, respectively). No relationship between age and vertical stiffness existed (r = ?0.06 for absolute and relative stiffness), or training history and vertical stiffness (r = ?0.01 and 0.00 for absolute and relative stiffness, respectively) existed. These results and others lend to suggest that vertical stiffness is not related to lower limb muscle strain injury.  相似文献   
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  • The Society for Scholarly Publishing's (SSP) Diversity, Equity, Inclusion, and Accessibility (DEIA) Committee began as a grassroots initiative in 2016.
  • Over a a period of 4 years, the committee evolved from a six-member task force to a large standing team consisting of more than 25 individuals.
  • The task force developed a strategic plan consisting of three major objectives that formed the basis of the group's strategic initiatives. The committee implemented several DEIA nitiatives that provided education and resources to SSP members about DEIA within their workplaces and promoted DEIA practices in the work that SSP committees were doing on behalf of the organization.
  相似文献   
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