Ophthalmic Presentation of Disseminated Tuberculosis with Relapse-Immunological Profile

TB as the cause of uveitis varies from 0.5 to 10.5%; low sensitivity of confirmatory laboratory investigations and inconsistency of diagnostic criteria leads to paucity of data. Diagnosis requires a high level of suspicion and is often presumptive based on indirect evidences. Interferon gamma, Interleukin-2 and Neopterin are key biomarkers in immuno-regulation of Mycobacterium tuberculosis infection. The relative shift from Interleukin-2 towards Interferon gamma (Interferon gamma/Interleukin-2) is more discriminatory for active tuberculosis. Protein carbonyl and Malondialdehyde, as oxidative stress markers, characterize active tuberculosis. A case of disseminated TB presenting with acute uveitis had a recurrent tubercular lymphadenitis after completing category I treatment under revised national tuberculosis control programme. The present study evaluates the potential utility of above mentioned biomarkers to predict atypical presentation in difficult cases of tuberculosis. Though tuberculous uveitis is amenable to treatment in early course of disease, the delay in diagnosis can have serious consequences for the patient.     

Attitudes of secondary school teachers towards inclusive education in New Delhi,India

This study was undertaken to determine the attitudes of secondary regular schoolteachers towards the inclusion of students with disabilities in New Delhi. A total of 470 teachers, working in schools managed by a private organisation in Delhi, returned the completed survey. A two‐part questionnaire was used in this study. Part one gathered information relating to personal and professional characteristics of the teachers. Part two was a 16‐item Likert scale titled, Attitudes towards Inclusive Education Scale. The major finding of the study was that the teachers in Delhi had positive attitudes towards the inclusion of students with special needs. This study also indicated that the teachers who were more positive about inclusive education were male, younger teachers (less than 40 years of age), less experienced (less than 10 years) and had postgraduate qualifications. In addition, the teachers who had a contact with a person with a disability and those who did not have a focus on disability during their preservice teacher education programmes were more positive towards inclusive education.     

Formula funding and decentralized management of schools-Has it improved resource allocation in schools in Sri Lanka?

Using the experience of the Educational Quality Inputs (EQI) Scheme in Sri Lanka the paper examines the distributional aspects of formula-based funding and efficiency of decentralized management of education funds in a developing country setting. The study finds that the EQI fund distribution is largely pro-poor. However, results show that to reduce disparities allocated funds need to be fully utilized. The findings of the study supports the hypothesis that qualified principals, adequate levels of human and physical resources and state level monitoring and support are needed for the success of education management at the school level.     

Some oxidative stress related parameters in patients with head and neck carcinoma

Forty cases of head and neck cancer were studied for plasma superoxide dismutase, malondialdehyde and thiol levels and results were compared with a group of forty normal healthy volunteers. Mean plasma superoxide dismutase activity was not found to be altered while malondialdehyde concentration was significantly higher when compared with the control group. On the other hand, mean thiol level was significantly lowered. The data suggests increased level of oxidative stress in patients with head and neck cancer.     

Patterns of Risk and Protective Factors Among Alaska Children: Association With Maternal and Child Well-Being

This study used population-representative data to examine associations of risk and protective factor patterns among Alaska Native/American Indian (AN/AI; N = 592) and non-Native (N = 1,018) children with maternal and child outcomes at age 3 years. Among AN/AI children, a high risk/moderate protection class was associated with child developmental risk and mothers being less likely to feel comfortable asking for help or knowing where to go for parenting information compared to a low socioeconomic status/high protection class. Among non-Native children, a moderate risk/high protection class was associated with child developmental risk and mothers being less likely to feel comfortable asking for help compared to a low risk/high protection class. Results provide insight on the intersection of risk and protective factors among Alaska families.     

‘Finding’ and ‘discovering’: How understanding researchers’ search and discovery behaviour informed the building of Cambridge Core

Key points

• Researchers most often visit publisher platforms to ‘find’ a specific article or chapter after ‘discovering’ available resources elsewhere.
• Keywords in the title and author names are the two most important criteria for identifying relevant material.
• Students consider access to be an important criterion for item selection.
• For both humanities and social sciences (HSS) and science, technology, and medicine (STM), user behaviour when identifying relevant content is remarkably similar.
• Students and researchers tend to gather content for later use rather than read it in detail as soon as they find it.