Forschungs- und Entwicklungsprojekte Virtuelle Maschinen: zSeries- und S/390-Partitionierung

Der gleichzeitige Betrieb mehrerer Gast-Betriebssysteme auf einem einzigen physischen Rechner unter einem Host-Betriebssystem ist eine leistungsfähige moderne Entwicklung. Bekannte Beispiele sind VMware für die IA32-Architektur sowie das Betriebssystem z/VM und die PR/SM-LPAR Einrichtungen der zSeries-Architektur. Die Nutzung eines Betriebssystems als Gast bedingt einen Leistungsverlust. Die als Partitionierung bezeichnete Zuordnung von Systemressourcen zu den einzelnen Gast-Betriebssysteme ist schwierig, wenn eine dynamische Anpassung an sich ändernde Lastprofile erforderlich ist. Diese Probleme lassen sich mittels Erweiterungen der Hardwarearchitektur adressieren, sowie durch Softwarestrukturen, welche diese Erweiterungen nutzen. Die Erweiterungen der Hardwarearchitektur gehen über das hinaus, was auf heutigen Rechnerarchitekturen wie IA32 oder Mips verfügbar ist. Der vorliegende Beitrag erläutert den optimalen Betrieb von Gast-Betriebssystemen und die begleitenden Partitionierungsmöglichkeiten auf der zSeries-Plattform und beschreibt die zusätzlichen Hardware- und Software-Einrichtungen, welche dies ermöglichen.     

Buddhist Wall Paintings at Nako Monastery,North India: Changing of the Technology Throughout Centuries

The technical study of wall paintings from the Buddhist temple complex at Nako, Western Himalayas, was one of the basic preconditions required for designing an appropriate conservation strategy. The complex, composed of four temples from the eleventh–twelfth century, offered a unique possibility to carry out a comprehensive research of technology and painting materials used in early and later western Tibetan Buddhist wall paintings as well as a comparative assessment with murals from other sites in the Western Himalayas. The study was based on extensive fieldwork and an integrated analytical approach comprising a wide range of non-destructive and micro-destructive methods. Answering the question of the coevality of paintings in the smaller temples with other original murals, the precise characterisation of binding media, the detection of the yellow dye gamboge and natural minerals posnjakite and brochantite identified for the first time in Himalayan murals, the clarification of technology of metal decoration, and the making of raised elements are some of the most exciting results which emerged from the research.     

Lighting the Shroud of Turin for Exhibition in 2015

ABSTRACT

Lighting a cultural heritage artifact requires balancing visual perception with preventive conservation, by providing the best lighting (in terms of spectral distribution and quantity) to enable the viewer to appreciate details and color, while limiting photo-induced degradation. The paper outlines the methodology applied by a multi-disciplinary team while lighting the Shroud of Turin at its last public exhibition in 2015. The methodology considered the special requirements of the Shroud, including exposure to ultraviolet light, while providing appropriate display conditions that would meet audience expectations. The desired appearance (readability of the body image and color) was defined with the help of Shroud researchers and confirmed by subjective tests, while appropriate light levels for preservation were set in agreement with standard requirements and using knowledge of the degradation of linen in visible and UV light. The installation provided a controlled environment and a managed visitor route to the Shroud, assuring excellent perception of both details and color, with the lowest illuminance level about 15?lx.     

Applying LDA Topic Modeling in Communication Research: Toward a Valid and Reliable Methodology

ABSTRACT

Latent Dirichlet allocation (LDA) topic models are increasingly being used in communication research. Yet, questions regarding reliability and validity of the approach have received little attention thus far. In applying LDA to textual data, researchers need to tackle at least four major challenges that affect these criteria: (a) appropriate pre-processing of the text collection; (b) adequate selection of model parameters, including the number of topics to be generated; (c) evaluation of the model’s reliability; and (d) the process of validly interpreting the resulting topics. We review the research literature dealing with these questions and propose a methodology that approaches these challenges. Our overall goal is to make LDA topic modeling more accessible to communication researchers and to ensure compliance with disciplinary standards. Consequently, we develop a brief hands-on user guide for applying LDA topic modeling. We demonstrate the value of our approach with empirical data from an ongoing research project.     

Placing Facebook

Facebook is challenging professional journalism. These challenges were evident in three incidents from 2016: the allegation that Facebook privileged progressive-leaning news on its trending feature; Facebook’s removal of the Pulitzer Prize-winning “Napalm Girl” photo from the pages of prominent users; and the proliferation of “fake news” during the US presidential election. Using theoretical concepts from the field of boundary work, this paper examines how The Guardian, The New York Times, Columbia Journalism Review and Poynter editorialized Facebook’s role in these three incidents to discursively construct the boundary between the value of professional journalism to democracy and Facebook’s ascendant role in facilitating essential democratic functions. Findings reveal that these publications attempted to define Facebook as a news organization (i.e., include it within the boundaries of journalism) so that they could then criticize the company for not following duties traditionally incumbent upon news organizations (i.e., place it outside the boundaries of journalism). This paper advances scholarship that focuses on both inward and outward conceptions of boundary work, further explores the complex challenge of defining who a journalist is in the face of rapidly changing technological norms, and advances scholarship in the field of media ethics that positions ethical analysis at the institutional level.     

Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo

BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.     

Health education for Somali Bantu refugees via home visits

Background: Somali Bantu refugees, with unique health information needs, created challenges for health and social service providers. Objectives: A service innovation was developed (i) to raise awareness, especially among local health and social service providers, about the Bantu refugees’ presence in the community, their culture, and their information needs and (ii) to deliver needed health information, emphasizing child health, to the Bantu mothers in their homes. Methods: The project consisted of: (i) a community conference targeting local health and social service providers, describing the refugees’ presence in the community, their culture, and information needs. (ii) Focus groups conducted with members of the Bantu population elicited additional information needs. (iii) Curriculum was developed based on identified needs, and (iv) the curriculum was delivered to the refugees in their homes. A clinical informationist and MP3 technology enhanced the project. Findings: Conference attendees’ evaluation responses indicated improved understanding of Bantu culture. Focus groups’ identification of health information needs provided a framework for the health education curriculum. A project website made educational materials available to other healthcare providers. Conclusions: The project raised awareness of the Bantus’ presence, culture, and information needs. Identification of other unmet needs demonstrated that additional support for refugees is required.     

Knee extensor and flexor torque development with concentric and eccentric isokinetic training

This study assessed muscular torque and rate of torque development following concentric (CON) or eccentric (ECC) isokinetic training. Thirty-eight women were randomly assigned to either CON or ECC training groups. Training consisted of knee extension and flexion of the nondominant leg three times per week for 20 weeks (SD = 1). Eccentric training increased ECC knee extension and flexion peak torque more than CON training. The ECC group improved acceleration time and time to peak torque with ECC movements versus the CON group. Slow-velocity ECC isokinetic training yielded greater ECC and similar CON torque development gains versus CON training over the course of 20 weeks in young women.