Critical success factors: How one multinational company develops global e‐learning

This research study examined how a multinational company determined what the critical success factors (CSFs) were for developing global e‐learning. The study analyzed how these CSFs were grouped together to make their management more efficient. There were 21 participants in the study who were key stakeholders from the United States, Europe, Latin America, and Asia. The results demonstrated that not all CSFs were deemed critical for every program and that what were considered CSFs early in the project often changed by the end of the project. In addition, the study showed that grouping the CSFs into common categories allowed the program development stakeholders to be more consistent and thorough in their ability to manage and address those CSFs throughout the project. Finally, the results demonstrated that for the study company, the best way to manage CSFs was to expand existing best practices and standard operating procedures to address global CSFs.     

Nearest neighbor search in metric spaces through Content-Addressable Networks

Most of the peer-to-peer search techniques proposed in the recent years have focused on the single-key retrieval. However, similarity search in metric spaces represents an important paradigm for content-based retrieval in many applications. In this paper we introduce an extension of the well-known Content-Addressable Network paradigm to support storage and retrieval of more generic metric space objects. In particular we address the problem of executing the nearest neighbors queries, and propose three different algorithms of query propagation. An extensive experimental study on real-life data sets explores the performance characteristics of the proposed algorithms by showing their advantages and disadvantages.     

Use of performance-enhancing drugs and the Internet

The use of physical performance-enhancing drugs is not limited to professional sports only, but has also been reported as common practice in recreational sports. A significant amount of epidemiological studies have highlighted the collective of fitness center visitors to be a high-risk group for using performance-enhancing drugs. From a sociological perspective, however, the decision to use performance-enhancing drugs (e.g., doping in the context of high-performance sport) is not an individual phenomenon only, but rather a result of social opportunity structures. This research article gives insight into enhancing-related Internet forums, in which the expertise of using and applying substances is passed on step by step. Using selected criminological learning theories, the “doping talk” in these social networks is hermeneutically reanalyzed and the Internet is exposed as a previously under-analyzed option for acquiring knowledge on the use of performance-enhancing drugs. This article shows that users of “doping platforms” are highly informed about doping and this offer of information acts like a knock-on effect to athletes who have so far abstained from doping. Consequently, future prevention models against the abuse of performance-enhancing drugs should consider the subcultural background of the milieu in which the athletes act.     

Public-Private Dynamics in Higher Education in the Western Balkans

The article analyzes the public-private dynamics in the context of eight Western Balkan countries (Albania, Bosnia and Herzegovina, Croatia, Former Yugoslav Republic of Macedonia, Kosovo, Montenegro, Serbia, and Slovenia). This article examines whether and to what extent these governments “level the playing field” between private and public higher education providers, not in the sense that they have equal chances to succeed, but that they all play by the same set of rules and are able to compete fairly. The article first addresses the emergence of a private higher education sector and the access of this sector to public resources. Next, it discusses the extent of “privatization” of public higher education institutions and whether these are prompted to be more market oriented. We find that the boundaries between the public and private sectors are blurred and the relations aggravated while each of the sectors is faced with its own set of challenges to legitimacy and long-term financial sustainability.     

2008年北京奥运会田径项目男子运动成绩分析

德国竞技杂志2005年第4期刊登了捷克学者泰林格尔(P·Tilinger)等人对自1972年至今所有已经举行过的奥运会和世锦赛前6名运动员的成绩进行了统计处理,其中,重点分析了110m跨栏、跳高、800m跑和铁饼项目,运用数理统计的外推法建立了男子田径各个项目的回归方程,对2008年第29届奥     

On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro

The in vitro study of liver functions and liver cell specific responses to external stimuli deals with the problem to preserve the in vivo functions of primary hepatocytes. In this study, we used the biochip OrganoPlate^TM (MIMETAS) that combines different advantages for the cultivation of hepatocytes in vitro: (1) the perfusion flow is achieved without a pump allowing easy handling and placement in the incubator; (2) the phaseguides allow plating of matrix-embedded cells in lanes adjacent to the perfusion flow without physical barrier; and (3) the matrix-embedding ensures indirect contact of the cells to the flow. In order to evaluate the applicability of this biochip for the study of hepatocyte''s functions, Matrigel^TM-embedded HepG2 cells were cultured over three weeks in this biochip and compared to a static Matrigel culture (3D) and a monolayer culture (2D). Chip-cultured cells grew in spheroid-like structures and were characterized by the formation of bile canaliculi and a high viability over 14 days. Hepatocyte-specific physiology was achieved as determined by an increase in albumin production. Improved detoxification metabolism was demonstrated by strongly increased cytochrome P450 activity and urea production. Additionally, chip-cultured cells displayed increased sensitivity to acetaminophen. Altogether, the OrganoPlate seems to be a very useful alternative for the cultivation of hepatocytes, as their behavior was strongly improved over 2D and static 3D cultures and the results were largely comparable and partly superior to the previous reports on biochip-cultured hepatocytes. As for the low technical needs, this platform has the appearance of being highly applicable for further studies of hepatocytes'' responses to external stimuli.     

Large-scale similarity data management with distributed Metric Index

Metric space is a universal and versatile model of similarity that can be applied in various areas of non-text information retrieval. However, a general, efficient and scalable solution for metric data management is still a resisting research challenge. In this work, we try to make an important step towards such management system that would be able to scale to data collections of billions of objects. We propose a distributed index structure for similarity data management called the Metric Index (M-Index) which can answer queries in precise and approximate manner. This technique can take advantage of any distributed hash table that supports interval queries and utilize it as an underlying index. We have performed numerous experiments to test various settings of the M-Index structure and we have proved its usability by developing a full-featured publicly-available Web application.