针刀松解法治疗膝骨关节炎临床对照研究

目的：通过与电针治疗膝骨关节炎的疗效进行对比，观察针刀对膝骨关节炎患者各项指标的影响以及总体疗效如何。方法：采用随机、对照的方法，试验组24例，采用针刀治疗；对照组24例，采用电针治疗。对比两组临床疗效。结果：（1）经过3周的治疗，电针组和针刀组均取得了一定的近期效果，与治疗前相比各项指标均有显著改善，两组的有效率比较无显著差异。（2）疗效的趋向性与治疗方法有关，针刀组更加趋向于临床治愈（P=0.04）。（3）两组患者治疗前后自身指标分值比较：疼痛、关节僵硬、生理功能、压痛、肿胀、关节活动度均有下降，具有统计学意义；针刀组与电针组治疗后各指标分值比较，疼痛、关节僵硬、生理功能、压痛、肿胀均无统计学意义。针刀组患者治疗后关节活动度显著优于电针组。结论：通过上述研究认为针刀治疗膝骨关节炎近期疗效良好，值得进一步深入研究。     

强化期刊出版风险意识提高危机防控化解能力

体制改革中面临的风险防控任务贯穿于期刊编辑出版的全流程。由于中华医学会主办期刊管办形式多样,该任务更具复杂性和艰巨性。结合学会百年办刊经验和多年来对学会期刊改革探索的实践,梳理总结出主要风险点。认为只有强化主办及出版单位对期刊编辑出版的风险防范意识,制订切实有效的监督机制和防范措施,才能从根本上将期刊出版工作中的风险降至最低。     

四川省民生建设的历史考察及经验启示

自解放至1978年期间,中共四川省委领导全省民生建设取得过巨大的成就,也有过沉痛的曲折,留下了深刻教训;十一届三中全会后,四川省委领导的民生建设飞速发展,成效显著。正反两个方面的经验教训在思想认识、政策路线、建设方法、具体举措和基本原则上启示着四川当前的民生建设。     

大学生就业指导理念和实践模式分析

在高校扩招的大背景下,大学毕业生就业形势愈发严峻,高校毕业生就业难问题已经成为当今社会难题之一。而解决这一问题的最终手段之一,就是各大高校有效的进行大学生就业指导工作。但是,高校现有的就业指导无论在理念还是在模式上都无法满足学生们的需求,需要进行行之有效的转变。     

《已故上校的女儿们》中的象征意象分析

《已故上校的女儿们》是著名短篇小说家凯瑟琳·曼斯菲尔德的经典之作。这篇小说独特的叙事结构、淡化的故事情节和巧妙转换的叙述角度为人们所津津乐道,与此同时,曼斯菲尔德对象征意象的娴熟运用也让这篇小说意味深长、回味无穷。作品中象征性意象分为三类,分别象征着父权主义、维多利亚时代妇女的希望和她们的实际地位。通过对这些意象的分析,读者可以更深刻地理解该小说及曼斯菲尔德的写作风格。     

Socio-scientific reasoning and environmental literacy in a field-based ecology class

The complex environmental challenges humanity faces require citizens who are scientifically and environmentally literate. Many environmental education programs are situated in the field where students are immersed in their learning. These field-based activities are engaging but may lack opportunities for students to develop critical thinking and reasoning skills necessary to be environmentally literate. We suggest a socio-scientific issue (SSI) based teaching approach can increase epistemic engagement and lead to student gains in scientific and environmental literacy. This study describes how we modified an existing field-based ecology course, framing the learning around a local environmental socio-scientific issue. We used a convergent parallel mixed-methods approach to examine the changes in socio-scientific reasoning (SSR) over time for high school students in this course as a measure of scientific and environmental literacy. Results indicate that a focused SSI field-based environmental education curriculum can support development of socio-scientific reasoning and environmental literacy competencies among high school students.     

美国佐治亚理工学院工业工程专业本科教学分析与借鉴

文章首先介绍了佐治亚理工学院工业工程本科专业的基本情况,然后分别从本科生专业课程要求、方向设置、课程设计、动手实践和创新能力的培养及教学方式和方法等方面进行了分析和对比.     

Application of network meta-analysis in the field of physical activity and health promotion

Continued advancement in the field of physical activity and health promotion relies heavily on the synthesis of rigorous scientific evidence. As such, systematic reviews and meta-analyses of randomized controlled trials have led to a better understanding of which intervention strategies are superior (i.e., produce the greatest effects) in physical activity-based health behavior change interventions. Indeed, standard meta-analytic approaches have allowed researchers in the field to synthesize relevant experimental evidence using pairwise procedures that produce reliable estimates of the homogeneity, magnitude, and potential biases in the observed effects. However, pairwise meta-analytic procedures are only capable to discerning differences in effects between a select intervention strategy and a select comparison or control condition. In order to maximize the impact of physical activity interventions on health-related outcomes, it is necessary to establish evidence concerning the comparative efficacy of all relevant physical activity intervention strategies. The development of network meta-analysis (NMA)—most commonly used in medical-based clinical trials—has allowed for the quantification of indirect comparisons, even in the absence of direct, head-to-head trials. Thus, it stands to reason that NMA can be applied in physical activity and health promotion research to identify the best intervention strategies. Given that this analysis technique is novel and largely unexplored in the field of physical activity and health promotion, care must be taken in its application to ensure reliable estimates and discernment of the effect sizes among interventions. Therefore, the purpose of this review is to comment on the potential application and importance of NMA in the field of physical activity and health promotion, describe how to properly and effectively apply this technique, and suggest important considerations for its appropriate application in this field. In this paper, overviews of the foundations of NMA and commonly used approaches for conducting NMA are provided, followed by assumptions related to NMA, opportunities and challenges in NMA, and a step-by-step example of developing and conducting an NMA.     

Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

广告信息传播研究

广告是人类社会发展到一定阶段的产物,是由广告主通过付费所获得的一种自我宣传手段,它借助一定的媒体,向目标公众或目标市场传播信息、思想、观念和自我形象等[1].根据广告的最终目的,广告可分为商业广告和公共服务性广告.广告信息传播主要由广告主、广告信息、广告媒介、广告受众等要素组成,在现代社会中,广告已突破经济的界限,渗透到社会的方方面面,广告与社会、与人类的关系日益密切.然而广告作为信息传播的一种特殊方式,具有特殊的目的和意义,广告本身也存在着特殊性.本文就广告信息传播的特殊性、广告信息传播中的信息污染及管理问题进行探讨.