Study of adenosine deaminase activity in various arthritic conditions

Aim of present study was to compare the adenosine deaminase (ADA) activity in various types of arthritis conditions with synovial effusion. No. significant difference was observed in ADA activity in serum of control and study groups but results have shown a definite pattern of ADA activity in synovial fluid in various arthritic conditions. The highest value of ADA activity was observed in synovial fluid of patients with tubercular arthritis followed by rheumatoid, septic, osteo and post traumatic arthritis. Thus measurement of ADA activity in synovial fluid can be used as a parameter of differential diagnosis of arthritis specially tubercular in initial stages.     

The effects of substrate and fluid provision on thermoregulatory and metabolic responses to prolonged exercise in a hot environment

A high ambient temperature reduces the capacity to perform prolonged exercise. Total carbohydrate oxidation is less, and thus glycogen depletion is not limiting. Fluid ingestion in the heat should, therefore, focus on maintenance of hydration status rather than on substrate provision. Six healthy males cycled to exhaustion at 60% of maximum oxygen consumption (VO 2max ) with no drink, ingestion of a 15% carbohydrate-electrolyte drink (1.45 - 0.29 litres) or ingestion of a 2% carbohydrate-electrolyte drink (3.12 - 0.47 litres). The ambient temperature was 30.2 - 0.6°C (mean - s ), with a relative humidity of 71 - 1% and an air speed of approximately 0.7 m.s -1 on all trials. Weighted mean skin temperature, rectal temperature and heart rate were recorded and venous samples drawn for determination of plasma volume changes, blood metabolites, serum electrolytes and osmolality. Expired gas was collected to estimate rates of fuel oxidation. Exercise capacity was significantly ( P ? 0.05) different in all trials. The median (range) time to exhaustion was 70.9 min (39.4-97.4 min) in the no-drink trial, 84.0 min (62.7-145 min) in the 15% carbohydrate trial and 118 min (82.6-168 min) in the 2% carbohydrate trial. The 15% carbohydrate drink resulted in significantly ( P ? 0.05) elevated blood glucose and total carbohydrate oxidation compared with the no-drink trial. The 2% carbohydrate drink restored plasma volume to pre-exercise values by the end of exercise. No differences were observed in other thermoregulatory or cardiorespiratory responses between trials. These results suggest that fluid replacement with a large volume of a dilute carbohydrate drink is beneficial during exercise in the heat, but the precise mechanisms for the improved exercise capacity are unclear.     

Attentional bias for exercise-related images

This research examined attentional bias toward exercise-related images using a visual probe task. It was hypothesized that more-active participants would display attentional bias toward the exercise-related images. The results showed that men displayed attentional bias for the exercise images. There was a significant interaction of activity level by gender, and simple slopes analysis showed that active women displayed attentional bias toward the exercise-related images and inactive women displayed attentional bias toward the control images. A similar analysis with explicit attention to the pictures as the outcome variable was not significant. These findings confirm that attention for exercise-related images can be captured automatically regardless of whether people report they are attending to them.     

The role of reduced frequency of knowledge of results during constant practice

Two experiments were conducted to further examine the effects of reduced knowledge of results (KR) frequency on the learning of motor skills during constant practice. In Experiment 1, participants in five KR conditions (100% KR, 50% KR-fade, 50% KR-reverse fade, 50% KR-alternative, and 50% KR-random) practiced a movement timing task. In Experiment 2, participants in two KR conditions (100% KR and 50% KR-fade) practiced a waveform reproduction task. The results of both experiments failed to indicate that reduced KR frequency was more effective in promoting learning than the 100% KR conditions. The present study adds to the increasing number of experiments that do not find a benefit of reduced KR frequency on learning in constant practice.