Carbohydrate gel ingestion during running in the heat on markers of gastrointestinal distress

The purpose of this study is to measure the effects of carbohydrate ingestion during exercise in the heat by measuring markers of gastrointestinal damage and inflammation. Methods: Active subjects (n?=?7) completed two 60-min running trials in a heated environment (70% VO₂max, 30°C). At minute 20 of exercise, subjects consumed a carbohydrate gel (Cho) (27?g), or a non-carbohydrate placebo (nCho). Plasma endotoxin, I-FABP, TNF-α, IL-6, IL-1β, IL-10, and MCP-1 were measured pre-exercise, 20-min post-exercise, and again 2-h, and 4-h post-exercise. Results: Endotoxin increased 20-min post-exercise compared to pre in the Cho trial only (p?=?.03). I-FABP levels increased 20-min post-exercise in the Cho trial only compared to pre-exercise (p?=?.003). I-FABP levels were also increased in Cho trial 20-min post-exercise when compared to same time point in the nCho trial (p?=?.032). TNF-α increased 20-min post-exercise in the Cho trial only compared to pre (p?=?.03). Plasma IL-6 concentration increased 20-min post-exercise when compared to pre in both the Cho (p?=?.002) and nCho (p?=?.009), but remained elevated at the 2-h time point in the nCho trial (p?=?.03). I-FABP and several plasma cytokines (TNF-α, MCP-1, Il-6) returned to baseline sooner in the Cho trial. Conclusions: Ingestion of carbohydrate gel during exercise in the heat enhances markers of gastrointestinal wall damage.     

Reading/Writing Multilingualism: language,literature and creativity in the multilingual classroom

This article examines the relationship between the discipline of ‘English Literature’ and the contemporary multilingual classroom. It argues that, although our field has often been cast as a kind of corrective to the ‘problem’ of language diversity by helping to teach language norms, literature can – and should – be made a preeminent space for students to reflect on their own experiences of language diversity, and to translate this into self‐reflexive critical tools to think about language in literature. As an example of this kind of practice in action, the article discusses the experience and outcomes of a project in the English Literature department at Queen Mary University of London, Reading/Writing Multilingualism, which involved year 10 and 12 students from two local secondary schools who have English as an additional language.     

Superstar effects on royalty income in a performing rights organization

This paper examines the economic accomplishments of individual members in a Performing Rights Organization (PRO), sometimes referred to as a Performing Rights Society. Today, there is the growing importance of intellectual property and copyright protection for authors and creators of literary, dramatic, musical, artistic and other intellectual works. The digital age has placed added pressure on songwriters, lyricists and composers in their ability to derive economic benefits from their intellectual creativity in the form of a copyright. Copyright laws protect and enable the creation of music by allowing authors and composers to license the control and use of their creations, and receive compensation in the form of royalty payments for their work. The PROs license, collect and distribute royalty payments for non-dramatic public performances of copyrighted musical works created and owned by its members or affiliates. In this paper, skewness and heavy tail of returns in the form of member royalty payments are estimated using the skew-normal and skew-t distributions in a parametric approach. We found strong evidence of the so-called ‘superstar effect’ in which the average royalty payment made by a PRO is still dominated by extreme outcomes, and relatively few members earned a substantial share of royalty payments from blockbuster hits that have endured over time. There is little evidence of smaller niche members dominating or replacing the ‘superstars.’ Economists and others will benefit from this empirical study which emphasizes a new understanding of the music industry from a PRO, member royalty payment and performance copyright perspective.     

The Early Reading Research: The impact of instructional psychology

The Early Reading Research (ERR), is a six-year research project investigating the most effective approaches to: improving reading standards; ensuring that every child can reach age and skill appropriate targets in reading; and, preventing the occurrence of reading difficulties. This article reviews the educational and psychological research into teaching reading and relates recent findings to theories and research emerging from instructional psychology, which underpins the 'framework for teaching reading' used within the ERR. Two studies are then summarised which evaluated the impact of the ERR reading framework. Study 1 involved a two-year experimental study where the progress of children following the ERR framework during reception and Year 1, was compared to that of children taught to read through their usual classroom methods. Study 2 involved a one-year study where the progress of a sample of children within the ERR was compared to children following the National Literacy Project. The article concludes by highlighting some implications of the ERR for educational psychologists (EPs), the field of special education and the National Literacy Strategy.     

Students’ experiences of academic success with dyslexia: A call for alternative intervention

This article describes a small‐scale study exploring the perspectives of five undergraduate students with dyslexia. Semi‐structured interviews were conducted in two universities in the UK. The interviews explored participants’ perceptions of their dyslexia label and how it had affected their academic success. The aim of the research was to identify facilitating factors that supported participants with dyslexia during their education. The following themes were identified: age of dyslexia identification, family support, dyslexic identity, self‐advocacy skills and learning resources. The study makes a case for an intervention for children and young people (CYP) with dyslexia that, in addition to remedial literacy support, explores self‐advocacy, thinking and study skills and facilitates positive academic self‐concepts. Future research could evaluate such an intervention for its effectiveness on CYP's social emotional well‐being and literacy skills.     

Social Networks and Archival Context: From Project to Cooperative Archival Program

This article highlights the objectives and outcomes of the multi-year Social Networks and Archival Context (SNAC) research and demonstration project and discusses related developments to establish a large-scale sustainable cooperative for maintaining information about creators of archival collections, leveraging the Encoded Archival Context—Corporate Bodies, Persons, and Families (EAC-CPF) standard. The article discusses processes developed to derive EAC-CPF records from existing EAD finding aids, MARCXML records, and original authority records, enrichment of those records from other sources, and the creation of a prototype research resource, providing integrated access to dispersed archival collections and the social-historical context of the collections.     

CrossRef's Text and Data Mining Services

CrossRef ( http://www.crossref.org/ ) is an association of scholarly publishers that develops shared infrastructure to support more effective scholarly communications. In May 2014, CrossRef launched CrossRef Text and Data Mining Services for its members. This article covers the thinking behind CrossRef launching this service, and the particular problems it aims to address around the collection of full‐text content for the purposes of text and data mining (TDM). It explains the technical aspects of the service for researchers and lets publishers know what they need to provide to CrossRef in order to participate and how to do so. It will also describe the pilot of CrossRef's TDM Services, and information on publisher uptake since the launch and how this can be measured, and the costs for joining or using the service.     

Searching ClinicalTrials.gov and the International Clinical Trials Registry Platform to inform systematic reviews: what are the optimal search approaches?

Background:

Since 2005, International Committee of Medical Journal Editors (ICMJE) member journals have required that clinical trials be registered in publicly available trials registers before they are considered for publication.

Objectives:

The research explores whether it is adequate, when searching to inform systematic reviews, to search for relevant clinical trials using only public trials registers and to identify the optimal search approaches in trials registers.

Methods:

A search was conducted in ClinicalTrials.gov and the International Clinical Trials Registry Platform (ICTRP) for research studies that had been included in eight systematic reviews. Four search approaches (highly sensitive, sensitive, precise, and highly precise) were performed using the basic and advanced interfaces in both resources.

Results:

On average, 84% of studies were not listed in either resource. The largest number of included studies was retrieved in ClinicalTrials.gov and ICTRP when a sensitive search approach was used in the basic interface. The use of the advanced interface maintained or improved sensitivity in 16 of 19 strategies for Clinicaltrials.gov and 8 of 18 for ICTRP. No single search approach was sensitive enough to identify all studies included in the 6 reviews.

Conclusions:

Trials registers cannot yet be relied upon as the sole means to locate trials for systematic reviews. Trials registers lag behind the major bibliographic databases in terms of their search interfaces.

Implications:

For systematic reviews, trials registers and major bibliographic databases should be searched. Trials registers should be searched using sensitive approaches, and both the registers consulted in this study should be searched.Clinical trials registers such as ClinicalTrials.gov and portals to trials registers such as the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) are increasingly used to identify ongoing or completed clinical trials. These resources offer important information on the methods and progress of trials likely to be of interest to a range of users, including researchers, clinicians, and patients. The extent to which these resources can be relied upon as a sole source of trials for inclusion in systematic reviews, including Cochrane systematic reviews (CSRs), is the subject of the research study reported here. This study also investigates the most efficient ways that librarians, information professionals, and other searchers can search these resources. Search efficiency was investigated by evaluating the overlap and unique yield of searches in the two resources and by testing four search approaches. The tested search approaches ranged from the very precise (single specific condition search term combined with a single specific intervention search term) to the very sensitive (at least two interventions terms).