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981.
Several studies on age-related cognitive decline in dogs involve laboratory dogs and prolonged training. We developed two spatial tasks that required a single 1-h session. We tested 107 medium-large sized dogs: “young” (N=41, aged 2.5–6.5 years) and “old” (N=66, aged 8–14.5 years). Our results indicated that, in a discrimination learning task and in a reversal learning task, young dogs learned significantly faster than the old dogs, indicating that these two tasks could successfully be used to investigate differences in spatial learning between young and old dogs. We also provide two novel findings. First, in the reversal learning, the dogs trained based on the location of stimuli learned faster than the dogs trained based on stimulus characteristics. Most old dogs did not learn the task within our cut-off of 50 trials. Training based on an object’s location is therefore more appropriate for reversal learning tasks. Second, the contrast between the response to the positive and negative stimuli was narrower in old dogs, compared to young dogs, during the reversal learning task, as well as the cognitive bias test. This measure favors comparability between tasks and between studies. Following the cognitive bias test, we could not find any indication of differences in the positive and negative expectations between young and old dogs. Taken together, these findings do not support the hypothesis that old dogs have more negative expectations than young dogs and the use of the cognitive bias test in older dogs requires further investigation.  相似文献   
982.
Purpose: The present study aimed to investigate whether or not eccentric-only training induced different sex-related adaptations in vastus lateralis muscle architecture and knee extensors strength. Methods: Thirteen healthy women and 13 healthy men were recruited. Vastus lateralis pennation angle, fascicle length, and muscle thickness, as well as knee extensors eccentric, isometric, and concentric peak torque and one-repetition maximum (1RM) were measured. Both women and men underwent a unilateral iso-load knee-extension eccentric-only training with 120% of the concentric 1RM, consisting of 4 sets × 10 repetitions twice a week for a total of 8 weeks. Results: Pennation angle increased in women (+ 14%, 95% CI [10, 17], effect size [ES] = 1.54) but not in men (+ 5%, 95% CI [?1, 11], ES = 0.28), while fascicle length increased in both women (+ 7%, 95% CI [4, 10], ES = 1.02) and men (+ 12%, 95% CI [8, 16], ES = 1.82) and muscle thickness increased in women (+ 13%, 95% CI [8, 18], ES = 1.11) and men (+ 11%, 95% CI [7, 15], ES = 0.89). In both women and men, eccentric (18%, 95% CI [11, 25], ES = 0.96, and 16%, 95% CI [9, 22], ES = 0.82, respectively), isometric (17%, 95% CI [11, 23], ES = 0.53, and 17%, 95% CI [10, 24], ES = 0.62), concentric (12%, 95% CI [7, 16], ES = 0.49, and 9%, 95% CI [5, 13], ES = 0.42) peak torque and 1RM (10%, 95% CI [6, 14], ES = 0.53, and 10%, 95% CI [5, 15], ES = 0.50) similarly increased after the intervention. Conclusions: This study showed that the adaptations in strength are not sex-dependent, but the increases in pennation angle only in women suggest that the changes in muscle architecture may depend on sex.  相似文献   
983.
The article sets the international context for the development of a curriculum of education for sustainable development and shows the directions being taken in the Francophone community. Building on a significant number of studies carried out in France, we constitute a typology of the positions of French-speaking researchers involved in those studies and contributing to the establishment of the national curriculum. This typology is constructed using a methodology based on the frequency of lexical occurrences in a bibliographic database, combined with a methodology of research on the social representations of the researchers of this community. We first present a broad comparison with the Anglo-Saxon sphere, we postulate that these positions influence the curriculum construction and raise the issue of the social responsibility of education science researchers in the face of international political demands.  相似文献   
984.
The purpose of this study is to replicate a study conducted by Hux, Marquardt, Skinner, and Bond (1999) in which the researchers explored the frequency of traumatic brain injuries (TBI) in the special education population as compared to the frequency of TBI among students in general education. Hux and colleagues (1999) found that roughly one-quarter of their sample received evaluations for special education services at some point, and that almost half their sample had sustained at least one TBI. Similarly, the current study explored the frequency of TBI in both general education and special education groups in a kindergarten through twelfth grade school. Results indicated that the sample in the current study reported a lower incidence rate of TBI than the general population as well as that in the 1999 study by Hux and colleagues. Additionally, only one student in the current sample (5% of TBI group) reported a history of TBI along with receiving special education services. Discrepancies between the current study and the Hux and colleagues (1999) study are explored, and possible reasons for the discrepancies are discussed.  相似文献   
985.
Systemic Lupus Erythematosus is an autoimmune disease with female preponderance. Anemia is found in 50% of Systemic Lupus Erythematosus patients. This is a cross sectional case control study with 30 female Systemic Lupus Erythematosus patients having inflammation associated anemia (Hemoglobin < 10.0 gm/dl) and 30 age matched controls with the aim to measure serum hepcidin and ferritin levels, correlate and study their role as homeostatic regulators of iron metabolism and utility as markers. Serum transferrin, ferritin, iron, total iron binding capacity, hsCRP, liver enzymes and renal parameters were analyzed by using automated analyser. Hepcidin levels were estimated by Sandwich-ELISA method. There was significant decrease in Iron (p < 0.0001), Iron Binding capacity (p < 0.0001), Transferrin (p < 0.0001) in patients, and a significant increase in inflammatory markers: hs-CRP (p < 0.0001), ESR (p < 0.0001) compared to controls. Significant increase in both Hepcidin (p < 0.0001) and Ferritin (p < 0.0001) was observed in patients with significant positive correlation (r = 0.711) with each other. Additionally, ferritin and hepcidin significantly positively correlated with hs-CRP and ESR (r = 0.526, 0.735); (r = 0.427, 0.742) respectively. Negative correlation with hemoglobin, iron, total iron binding capacity and transferrin with hepcidin (r = ? 0.80, ? 0.307, ? 0.553, ? 0.584) and ferritin (r = ?0.722, ? 0.22, ? 0.654, ? 0.728) was observed respectively. On ROC analysis both hepcidin and ferritin has sensitivity of 96.7%, specificity of 100% at cut-off values of 110 and 49 respectively. AUC of hepcidin was 0.993 and ferritin was 0.978. We have established a positive linear correlation between Hepcidin and Ferritin levels in disease activity and the changes correlated with the inflammatory state and anemia in patients, making them important mediators and potential markers of inflammation associated anemia.  相似文献   
986.
987.
Imagined Adulthood: Resources,plans and contradictions   总被引:1,自引:1,他引:0  
In this paper we illustrate the contradictory consequences of female individualization by exploring young people's imagined futures, drawing on an analysis of 'lifelines' collected as part of an ongoing longitudinal qualitative study of young people's transitions to adulthood. We discuss the method and compare lifelines across the sample. We suggest that while there are areas of consensus (such as the hetero-normative goal of marriage and children by 35) the traditionally gendered transitions to adulthood are under pressure, a pressure that is exerted most strongly by working class young people. Through three contrasting case studies we illustrate how the ways in which young people imagine their futures are constrained by the resources and possibilities of their particular social locations.  相似文献   
988.
989.
990.
It is acknowledged that appropriate support and training are essential if talented individuals are to fulfil their potential. The early identification of talented athletes is an increasingly important consideration for researchers and practitioners alike. Once talented individuals have been detected, crucial but limited support resources can be optimally deployed to ensure that their needs are met and that their gifts are developed. However, there is considerable disagreement among experts on what talent is, and which factors can reliably be used within talent identification processes. This paper explores prerequisites to success in sport, and the comparative efficacy of employing these prerequisites within talent identification schemes. It is proposed that talent needs to be reconceptualized so that talent identification and talent development processes are perceived to be dynamic and interrelated. Additionally, the need to place greater emphasis on the capacity of a child to develop in sport and the psychological factors that underpin this process is highlighted. To this end, it is advocated that talent identification and development schemes, while emphasizing the multidimensional nature of talent, need to recognize the essential role of psychology in the ability of individuals to fulfil their sporting potential.  相似文献   
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