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31.
Ajay Kumar T. A. Venkita Subramanian Usha P. Sharma 《Indian journal of clinical biochemistry : IJCB》1992,7(2):165-168
Protein fraction termed P2 was obtained from sonicates of Mycobacterium smegmatis, subjected to ammonium sulphate precipitation. P2 fraction was further fractionated into 4 fractions (PeakI-IV) by DEAE cellulose ion-exchange chromatography. ELISA was performed
on the sera of 104 tuberculous cases and 62 controls, using P2 fractions Peak I as test antigens. Though the mean ELISA values in tuberculous cases were higher than the controls, no statistically
significant difference was found between the two. Antigens P2, Peak I and IV were tested on Western blots with pooled sera from tuberculous cases as well as controls. P2 fraction, Peak-I and IV were separated on PAGE-SDS, electroblotted onto nitrocellulose Sheets and the blots were subjected
to ELISA. Peak IV appeared as a single band (M.W. 55,000). P2 fraction exhibited some discriminatory bands on development of blots. 相似文献
32.
Praveen Sharma P. K. Sharma D.Sc. J. Pramod L. K. Kothari Rashmi Ranka Sushma Sharma 《Indian journal of clinical biochemistry : IJCB》1989,4(1):62-64
Sixteen weeks of chronic vitamin C deficiency, induced in guinea pigs by restricted vitamin C intake, resulted in a marked
increase in the serum total LDL- and VLDL- cholesterol, triglycerides and total lipids. HDL-cholesterol decreased resulting
in a highly significant increase in LDL/HDL ratio. The results reconfirm that vitamin C deficiency causes changes in blood
lipid profile which could promote atherogenesis. 相似文献
33.
34.
Sashi Sharma Jenny Young-Loveridge Merilyn Taylor Ngärewa Häwera 《Asia Pacific Journal of Education》2011,31(4):503-519
This paper focuses on the perspectives of Years 7 and 8 Pasifika students on mathematics learning, in particular their views about the communication of solution strategies with others (their peers), and their teacher. Pasifika students' ideas about the importance of communicating their mathematical reasoning and strategies to peers and teachers were analysed and themes identified. While most students were in agreement about the importance of explaining their thinking to others, there was considerable variation in the reasons they gave for their views. The findings are interpreted in relation to socio-cultural theory and recent writing about requirements for citizenship in the twenty-first century. 相似文献
35.
Pushpendra Singh Kuldeep Sharma Dipika Shaw Anudita Bhargava Sanjay Singh Negi 《Indian journal of clinical biochemistry : IJCB》2023,38(4):418
Human Coronaviruses (hCoVs) belongs to the enormous and dissimilar family of positive-sense, non-segmented, single-stranded RNA viruses. The RNA viruses are prone to high rates of mutational recombination resulting in emergence of evolutionary variant to alter various features including transmissibility and severity. The evolutionary changes affect the immune escape and reduce effectiveness of diagnostic and therapeutic measures by becoming undetectable by the currently available diagnostics and refractory to therapeutics and vaccines. Whole genome sequencing studies from various countries have adequately reported mosaic recombination between different lineage strain of SARS-CoV-2 whereby RNA dependent RNA polymerase (RdRp) gene reconnects with a homologous RNA strand at diverse position. This all lead to evolutionary emergence of new variant/ lineage as evident with the emergence of XBB in India at the time of writing this review. The continuous periodical genomic surveillance is utmost required for understanding the various lineages involved in recombination to emerge into hybrid variant. This may further help in assessing virus transmission dynamics, virulence and severity factor to help health authorities take appropriate timely action for prevention and control of any future COVID-19 outbreak. 相似文献
36.
Suman B. Sharma Seema Garg Abhinav Veerwal Sridhar Dwivedi 《Indian journal of clinical biochemistry : IJCB》2008,23(4):334-336
Premature coronary artery disease (CAD) is common in India. We, therefore, studied oxidative stress, dyslipidemia, and high
sensitivity-C reactive protein (hs-CRP) levels in young CAD patients. Present study consisted of male CAD patients below 40
years and age and sex matched healthy controls (n=30 each). Fasting blood samples were analyzed for serum lipid profile, malondialdehyde,
antioxidant enzymes and hs-CRP levels. Dyslipidemia was observed in 90% of the young CAD patients, of which 72.2% showed increased
serum triglycerides and decreased HDL-cholesterol. LDL-cholesterol levels were high in 77.8%. Serum malondialdehyde and hs-CRP
levels were increased significantly (p<0.0001) as compared to controls. hs-CRP levels were in high risk range in all the young
patients. However, glutathione peroxidase activity was reduced significantly (p<0.05). Our data suggests that elevated hs-CRP
levels along with dyslipidemia and oxidative stress adds to the predictive value of premature CAD in young Indians. 相似文献
37.
N. Khanna A. Garg K. K. Sharma R. Khosla 《Indian journal of clinical biochemistry : IJCB》1997,12(1):86-90
In the present study which was aimed to see the effect of zinc on pentylenetetrazole induced convulsive threshold in rats we found that zinc sulfate 100 μg intracerebroventricularly) and pentylenetetrazole (50 mg/kg intraperitoneally) produced dose related seizure activity; however, pretreatment with zinc decreased the threshold, increased the severity, incidence of multiple seizures and total duration of pentylenetetrazole induced seizures. Diazepam (5 mg/kg intraperitoneally) pretreatment increased the threshold and lowered the incidence of convulsions in zinc induced seizures which further confirms that the convulsive effect of zinc is through inhibition of gamma aimino butyric acid. 相似文献
38.
This article reports on the third phase of a larger study that explored the perceptions of teachers about distributed leadership practices for inclusive education (IE) in primary schools involved in IE reform in Bangladesh. The Distributed Leadership Practice for Inclusive Education scale was developed specifically for this study to collect data. Participants for the present study were head teachers and teachers from 308 public primary schools. The results of this study indicate that teachers perceived that distributed leadership practices for IE were present in primary schools in Bangladesh. The findings indicate that teachers' perceptions about distributed leadership practices for IE have a significant positive correlation with their satisfaction about the implementation of IE policy. 相似文献
39.
The purpose of this paper was to investigate Malaysian primary pre-service teachers’ perceptions of students’ disruptive behaviour and their self-reported strategies to prevent and to manage such behaviours. Results indicate that Malaysian pre-service teachers understand disruptive behaviours to be those that disrupt the learning and teaching process. They identified the cause of student disruptive behaviour as factors residing within the individual student. Pre-service teachers here reported preventative strategies in terms of changing teaching strategies and threats to use punishment. When addressing students’ disruptive behaviour, pre-service teachers reported that they would use one-to-one counselling with students and remove tokens or hold back rewards. A discussion regarding the implications for teacher education institutions and future research concludes this paper. 相似文献
40.