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71.
Anshita Aggarwal Sant Ram Abhilasha Garg Rimesh Pal Anil Bhansali Priyanka Singh Sadhna Sharma J. S. Thakur Naresh Sachdeva Sanjay Kumar Bhadada 《Indian journal of clinical biochemistry : IJCB》2021,36(1):67
We aimed to estimate metabolic bone profile in a large cohort of healthy, adult Indian population to generate reference standards of serum calcium, phosphate and alkaline phosphatase (ALP), 25 (OH) Vitamin D and iPTH, and also to find out the prevalence of Vitamin D deficiency in healthy population. Apparently healthy people in the age group of 20–80 years, residing in the union territory of Chandigarh were chosen. Fasting samples for serum calcium, phosphate, albumin, alkaline phosphatase (ALP), 25 (OH) D and iPTH were collected and were processed on the same day. We recruited 930 healthy subjects from different subsectors of Chandigarh. Final analysis was done for 915 subjects. Out of this, 530 (58%) were women and 385 (42%) were men. The study participants were divided into two groups, less than and more than 50 years for the men and pre and post-menopausal for the women. The serum calcium, phosphate, ALP and iPTH were significantly higher in the post-menopausal women compared to the pre-menopausal women. The median plasma 25 (OH) D in men and women was 12.5 ng/mL and 14.3 ng/mL, respectively. 25 (OH) D deficiency was seen in 65.4% of individuals. 25 (OH) D levels co-related negatively with iPTH levels (r = − 0.4, p < 0.0001), and showed an increasing trend with age. We have thus presented metabolic bone profile of healthy, adult north Indian population. These reference values can be used for diagnosis and monitoring of various MBDs. Vitamin D deficiency is still rampant in our population in spite of increasing awareness. 相似文献
72.
S. B. Sharma S. Dwivedi K. M. Prabhu Narendra Kumar M. C. Baruah 《Indian journal of clinical biochemistry : IJCB》1999,14(2):245-248
Serum lipid profile, apolipoprotein-B (apo-B), malondialdehyde levels(MDA) and superoxide dismutase (SOD) activity were assessed
in 12 cases of xanthelasma with and without coronary artery disease (CAD)/hypertension (HTN) and results are compared with
healthy controls. Dyslipidemia was found in 65% cases of xanthelasma as compared to 20% healthy controls. Xanthelasma patients
had significantly high malondialdehyde (MDA) levels (p<0.01) and significantly decreased (p<0.05) SOD activity as compared
to controls. Among xanthelasma patients, xanthelasma with CAD/HTN showed higher total cholesterol (236±32.7 vs 188±24.7 mg/dl),
low density lipoprotein cholesterol (157±35.5 vs 113±16 mg/dl) and Apo-B (120.5±9.4 vs 114±19.2 mg/dl) levels as compared
to xanthelasma without CAD/HTN. Results of our study indicate that xanthelasma patients with increased apo-B, MDA and decreased
SOD need cardiovascular monitoring. 相似文献
73.
The authors analyzed data from 5,528 American Counseling Association members to examine advocacy beliefs and behavior regarding Medicare reimbursement and advocacy for counselors. Nearly half (49.3%) of the respondents had participated in one or more forms of Medicare reimbursement advocacy. Advocacy participation differed significantly by professional status. 相似文献
74.
Reflective learning can assist a learner’s purposeful and conscious manipulation of ideas toward meaningful learning and knowledge
integration. Blogs have been used to support reflection, but Blogs usually do not provide overt mechanisms for students to
make connections between different parts of an experience, which is integral to reflective activity. A blogging-mapping tool
was designed to support the reflective learning process. The tool allowed students to write blog posts, attach up to five
keywords to each post, and link the keywords on a concept map. This study aimed to seek patterns of participants’ use of the
tool, including evidence of reflective learning, identified as integration between concept maps and blogs. Nine graduate students
participated in the study for a semester. Data analysis included examining concept maps for knowledge integration over time.
Participants’ various mapping activities implied different levels of thinking. Some participants’ final concept maps showed
signs that they tried to integrate knowledge around the content area. Yet, the inconsistent and inconclusive patterns of participants’
concept mapping activities signaled that more strategies were needed to sustain their commitment. 相似文献
75.
76.
Rapid extinction of species is one of the most serious ecological problems faced by humanity today. Species are disappearing
at a pace unprecedented in the history of the planet putting the very future of life at risk. The irony is that the root of
the crisis is another species, Homo sapiens rather than some physical events that is poised to threaten its own survival. This article gives a brief introduction to
the crisis, its consequences and possible mitigation strategies. 相似文献
77.
78.
Alannah K. A. McKay David B. Pyne Peter Peeling Avish P. Sharma Megan L.R. Ross Louise M. Burke 《Journal of sports sciences》2019,37(5):553-559
Carbohydrate (CHO) availability could alter mucosal immune responses to exercise. This study compared the effect of three dietary approaches to CHO availability on resting and post-exercise s-IgA levels. Elite race walkers (n = 26) adhered to a high CHO diet (HCHO), periodised CHO availability (PCHO) or a low CHO/high fat diet (LCHF) for 3 weeks while completing an intensified training program. HCHO and PCHO groups consumed 8.0–8.5 g.kg?1 CHO daily, with timing of ingestion manipulated to alter CHO availability around key training sessions. The LCHF diet comprised 80% fat and restricted CHO to < 50 g.day?1. A race walk test protocol (19 km females, 25 km males) was completed at baseline, after adaptation, and following CHO restoration. On each occasion, saliva samples were obtained pre- and post-exercise to quantify s-IgA levels. Resting s-IgA secretion rate substantially increased ~ two-fold post-intervention in all groups (HCHO: 2.2 ± 2.2, PCHO: 2.8 ± 3.2, LCHF: 1.6 ± 1.6; fold-change± 95% confidence limits), however, no substantial differences between dietary treatments were evident. Post-exercise, substantial 20–130% increases in s-IgA concentration and 43–64% reductions in flow rate occurred in all dietary treatments, with trivial differences evident between groups. It appears that high volume training overrides any effect of manipulating CHO availability on mucosal immunity in elite athletes. 相似文献
79.
Vanita Sharma 《Cultural and Social History》2013,10(4):411-428
ABSTRACTThis article explores the creation and transmission of second generation memories concerning the 1947 Partition of British India. The research is based on oral interviews with Punjabi families who migrated because of Partition and now live in Lahore and Delhi. It explores how Partition memories have been transmitted across generations within these families, and also examines similarities and differences between how the second generation interviewees from Delhi and Lahore remember Partition. It demonstrates that the second generation have not passively accepted everything that the first generation, or the state, has told them about Partition. The second generation's memories are also shaped by their age, nationality, religion and class, and the nature of contemporary politics. 相似文献
80.
Cystic fibrosis is a common autosomal recessive disorder usually found in population of white Caucasian descent. Now it is
well documented the presence of CF disease in India with the advancement of laboratory testing. As once it was thought non
existence of this disease in our population. Most of the phenotype of CF disease was in accordance of western population.
Genetic analysis of CFTR gene in Indian CF patients revealed that most common mutation was delta F508 mutation. However, it
was less than Caucasian population. CFTR mutations are also a causative factor in the pathogenesis of male infertility due
to obstructive azoospermia. There are two most common mutation viz. IVS8-T5 and delta F508 which are responsible for congenital
absence of vas deferens in male infertility patients. Elevated levels of sweat chloride at two occasions along with the presence
of two mutations in CFTR gene was gold standard method for diagnosis of CF disease. It is noteworthy here that due to magnitude
of Indian population, the total CF disease load would be more than many European countries. Clinical data demonstrate the
prevalence of both classical and genetic form of CF in India. 相似文献