论网络时代信息资源的开放存取

信息技术推动社会发展,网络的广泛应用带动了信息存储和传播方式的变更。网络环境下,为推动资源的免费利用,国外开展了开放存取运动,这是传统出版方式和信息获取方式的变革,促进了科研工作的大力发展。在开放存取中,资源形式多种多样,资源的利用非常便利,交流十分便捷,作者提交论文选择性付费,读者利用资源完全免费。     

Effect of Lecithin on <Emphasis Type="SmallCaps">d</Emphasis>-Galactosamine Induced Hepatotoxicity Through Mitochondrial Pathway Involving Bcl-2 and Bax

Twenty four Wistar strain albino rats were used for the investigations. Lecithin 50 and 100 mg/kg b wt was administered for 1 week by oral route. Liver damage was induced by intra peritoneal administration of 400 mg/kg b wt d-galactosamine on the last day. At the end of the study animals were sacrificed and liver enzyme levels, histopathology, mitochondrial integrity, expression of p53, Bax and Bcl-2 mRNA levels were studied. Increases in the liver enzyme levels by d-GalN were significantly inhibited by pretreatment with lecithin. Histopathological observation further confirmed the hepatoprotective effect of lecithin. In addition, the disruption of mitochondrial membrane, up regulation of Bax and down regulation of Bcl-2 mRNA levels in the liver of d-GalN intoxicated rats were effectively prevented by pretreatment with lecithin. The results of the present study validate our conviction that d-GalN causes hepatic damage via mitochondrial pathway involving Bax and Bcl-2.     

"985工程"高校信息公开的效果分析 ——基于高校门户网站数据

自《高等学校信息公开办法》(以下简称《办法》)颁布以来,高校成为信息公开的义务主体,但据统计结果来看,高校信息公开与教育部所要求的政策标准还存在差距,政策效果不明显。文章结合高校门户网站所公开信息的相关内容及数据,利用调查研究法和链接分析法,对《办法》实施以来的政策效果进行定性和定量结合分析,并借鉴国外的政策经验来探索我国的解决之道。     

基于模糊综合评价法的学生入党评价

学生入党是成长过程中的重要事情之一,但如何对学生进行综合评价也是件辛苦的事,本文利用模糊数学的综合评价法,给出了学生入党的模糊综合评价模型。     

一个基于WEB的博客网站系统设计

随着计算机网络技术的不断发展,BLOG(博客)作为WEB的一个典型应用,为用户在网络平台上提供了一种简单有效的在线交流途径。故本文对一个博客系统进行了总体设计和详细设计,并实现了系统前台网站部分的代码。     

Preliminary studies on the hypoglycaemic effect ofAbroma augusta in alloxan diabetic rats

The hypoglycemic effect of the aqueous extract ofAbroma augusta (Family: Steculiceae) was studied in normal as well as alloxan diabetic rats. Treatement of diabetic rats with 4 ml (4gm dry weight) of agueous extract ofA. augusta for 16 weeks resulted in gradual but significant fall in fasting blood glucose and improvement in glucose tolerance. Serum total and LDL cholesterol and triacylglycerol which increased in diabetic rats showed improvement. These results show that the water extract ofA. augusta has both hypoglycemic and hypocholesterolemic effects.     

Serum anti — TPO levels in benign and malignant breast tumors

Breast cancer is a hormone dependent neoplasm. Conflicting results regarding the clinical correlation between breast cancer and thyroid diseases have been reported. The objective of this study was to determine the association of anti — TPO levels in patients having complaints of a lump in breast. Serum samples and Fine needle aspiration cytology (FNAC) samples were collected from 31 female patients with a lump in breast between the age group of 20–75 years. 31 age matched normal healthy controls were also examined for the same parameters. Serum samples were analyzed for its anti — TPO levels. FNAC reports confirmed patients as having duct cell carcinoma. They had raised serum anti — TPO levels compared to controls. FNAC results of others (n=26) were reported as fibroadenoma whose anti — TPO levels were less than the controls.     

陶渊明诗文平淡自然之风构成因素探析

陶渊明的诗文风格以“平淡自然”为主,其平淡而不枯淡,其中充满了丰润的生机。这种平淡之风,是很多因素共同形成的,题材的选取、语言的朴质自然、意境的浑然天成等皆为陶渊明诗歌平淡之风形成的主要原因。     

Lipoprotein (A): Better assessor of coronary heart disease risk in south Indian population

In an attempt to search for risk factors which can explain the increasing prevalence of coronary heart disease (CHD) in Indian population, we conducted a case-control study to assess the association of Lipoprotein (a)(Lp(a)) with CHD. One hundred and fifty one consecutive patients with clinical and angiographic evidence of CHD and forty-nine healthy controls were drawn for the study. Triglycerides, very low density cholesterol (VLDL-C), total cholesterol (total-C)/high density cholesterol (HDL-C) ratio, low density cholesterol (LDL-C)/HDL cholesterol ratio and Lp(a) were found to be higher in patients than controls. In female sex and in those with family history of CHD, higher total and LDL cholesterol levels were observed to be associated with higher Lp(a) levels. Lp(a) levels were also found to be higher in triple vessel disease than other vessel disease patients. Significant difference in Lp(a) levels were observed between normal coronaries vs. single and triple vessel disease(P<0.05) and also between single vs. double and triple vessel disease (P<0.01).Lp(a) levels correlated positively with vessel severity(P<0.005). Lp(a) levels >25 mg/dl were associated with coronary heart disease (Odds ratio 1.98 P<0.05 95% CI 0.007–1.18). Our findings suggest a cut-off level of 25mg/dl for determination of risk of CHD. Studies from different areas involving larger sample size are needed to confirm the findings of the present study.     

健美专项课教学对大学生身心群影响的实践研究

本文以广东嘉应学院健美选修班学生为研究对象,通过一年的健美专项课教学和训练,对授课前后学生身体形态、机能、素质、心理和社会适应能力等各项指标进行比较分析和研究。结果表明：健美专项课教学不仅能快速有效地改善大学生身体形态、机能和素质,而且对大学生的心理素质、社会适应能力、审美能力等诸多方面具有良好的促进作用。