A Practical Introduction to Authoring for Computer-Assisted Instruction. Part 5: PHILVAS

Interactive videodisc technology is likely to have a significant impact upon many aspects of education and training. However, before this medium can be effectively utilized considerable attention must be given to overcoming the present problems associated with courseware authoring. Solutions to these problems are to be found in the provision of suitable courseware development aids. In particular, there is a requirement for a powerful and easy-to-use author language. This paper describes the approach used by the PHILVAS authoring system.     

RELATIONSHIPS BETWEEN PSYCHOLOGICAL WELLBEING OF THAI COLLEGE STUDENTS,GOAL ORIENTATIONS,AND GENDER

This paper examined the direct and interaction effects of students’ learning and performance‐avoidance goal orientations on their psychological wellbeing and a moderating role of students’ gender in these relationships. Using 564 self‐reports of freshman college students in a Thai university, we found students’ psychological wellbeing to be positively related to their learning goal orientation and negatively related to their performance‐avoidance goal orientation. Additionally, the negative relationship between students’ performance‐avoidance goal orientation and psychological wellbeing was stronger for men than women. Lastly, differences in students’ psychological wellbeing between men and women became more pronounced with increases in learning goal orientation for students with low levels of performance‐avoidance goal orientation, but not for students with high levels of performance‐avoidance goal orientation. These findings were obtained after controlling for students’ grade point average and academic program.     

The trials and tribulations of partnerships in refugee settlement services in Australia

The ascendency of neoliberal ideas in education and social policy in the 1980s and 1990s was succeeded in the new millennium by a ‘new’ social democratic commitment with emphases on community empowerment, building social capital and a ‘whole of government’ approach to partnering with civil society to meet community needs. In Australia, this approach has resulted in the development of partnerships between schools and community organisations formed as part of a targeted, holistic approach to service delivery to meet the settlement and educational needs of refugee youth. Drawing on interviews conducted with community workers and government officers involved in the school–community partnerships, we document how these partnerships are working ‘on the ground’ in Queensland schools. We analyse our findings against the international literature on changing notions of neoliberal governance, and discuss the implications of the shift to the ‘partnering state’ for schools and community organisations working with refugee young people.     

Relationship between perceptions of classroom climate and institutional goal structures and student motivation,engagement and intention to persist in college

Disengagement and a lack of motivation have been found to be the major reasons for student drop out from higher education. In order to broaden our understanding of institutional and personal factors associated with intention to complete a college degree, this investigation examined the relationship between students’ perceptions of classroom climate and institutional goal structures and their motivational orientation, engagement and intention to persist in college. Data was collected from first-year students (N = 1778) enrolled in an institution of higher education near Bangkok, Thailand. The results indicate that perceptions of classroom climate and institutional goal structures have significant associations with students’ motivational orientations and levels of engagement and contribute to intention to persist in college.     

A biologically active constituent of withania somnifera (ashwagandha) with antistress activity

In Ayurvedic medicine,Withania somnifera (Ashwagandha) is well known for its anti-stress activity. A passive rat experimental model, where the animals are subjected to multiple stress of cold, hypoxia, restraint (C-H-R) has been developed to evaluate adaptogenic properties of various fractions of W. somnifera root extracts. We have carried out extraction of roots of W. somnifera with water and further isolated one of the active constituents called compound X and also tested its anti-stress activity in C-H-R model. The effect of administration of W. somnifera water suspension (360 mg/Kg bw) and compound X (20mg/Kg bw) on the fall and recovery of colonic temperature was noted. There was an increase of ≈38% and ≈54% in the time taken to attain T_rec 23°C by rats given a single dose of fresh aqueous suspension and biologically active constituent (Compound X) respectively, where as decrease in the recovery time to attain T_rec 37°C is ≈13% and ≈33% respectively, as compared to control group. It is clear that rats treated with the fresh aqueous suspension and compound X ofWithania somnifera, could withstand the multiple stress of C-H-R better than control group.     

Effect of ageing on some free radical scavengers and the metabolic consequences in rats

Activities of antioxidant enzymes involved oxygen free radical metabolism in the liver and lung were investigated in 2,4, and 30 months old Wistar albino rats. The levels of SOD, GSH-Px, GSH and protein-SH were decreased whereas MDA increased, in the liver as well as the lung of the old rats (30 months old) compared to the young rats (2 and 4 months old). The data suggests that the failure of the free radical protective mechanism may be one of the important contributors to the process of ageing.     

Probing transient protein-mediated DNA linkages using nanoconfinement

We present an analytic technique for probing protein-catalyzed transient DNA loops that is based on nanofluidic channels. In these nanochannels, DNA is forced in a linear configuration that makes loops appear as folds whose size can easily be quantified. Using this technique, we study the interaction between T4 DNA ligase and DNA. We find that T4 DNA ligase binding changes the physical characteristics of the DNA polymer, in particular persistence length and effective width. We find that the rate of DNA fold unrolling is significantly reduced when T4 DNA ligase and ATP are applied to bare DNA. Together with evidence of T4 DNA ligase bridging two different segments of DNA based on AFM imaging, we thus conclude that ligase can transiently stabilize folded DNA configurations by coordinating genetically distant DNA stretches.