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61.
New necessary and sufficient conditions, which are also algorithmic in nature, are obtained for the decomposition of a multivariable reactance function or a multivariable positive real function into a sum of several single variable reactance functions or several single variable positive real functions, respectively. 相似文献
62.
A. Madhavi Reddy Y. N. Rao Yogendra Singh Alpana Saxena 《Indian journal of clinical biochemistry : IJCB》1995,10(2):66-71
Adenosine deaminase and protein tyrosine phosphatase activities in liver and peritoneal macrophages were estimated in control,
streptozotocin induced diabetes and insulin treated diabetic groups of Swiss albino mice. Both the enzyme levels were elevated
while glycogen content decreased in the liver of diabetic group of animals as compared to controls, while in insulin treated
group, they were comparable to control levels. In macrophages also, both adenosine deaminase which plays an important role
in their maturation and protein tyrosine phosphatase enzyme involved in their activation were high in diabetic group, whereas
in insulin treated diabetic group, the values were comparable to control levels. *** DIRECT SUPPORT *** A00FN011 00003 相似文献
63.
K. Sudhakar M. Sujatha S. Ramesh Babu P. Padmavathi P. P. Reddy 《Indian journal of clinical biochemistry : IJCB》2004,19(1):21-23
Calcium plays an important role in the pathophysiology of essential hypertension. Serum calcium levels were measured in 117
subjects with essential hypertension and 77 first-degree relatives. The results showed that serum calcium levels were significantly
(p<0.01) decreased in both males and females with essential hypertension and their first-degree relatives when compared with
the normotensive controls. This is the first study in Indian population. 相似文献
64.
S. Ramesh Babu M. D. Sadhnani M. Swarna P. Padmavathi P. P. Reddy 《Indian journal of clinical biochemistry : IJCB》2004,19(1):45-49
Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often
associated with altered serum gonadotropins and testosterone. FSH, LH and testosterone levels were estimated in 96 infertile
men of whom 35 were azoospermic, 35 were oligozoospermic, 11 were with varicocele and 15 were with histopathological abnormalities
like hypospermatogenesis, spermatid arrest and sertoli-cell only syndrome. Results showed statistically significant (p<0.05),
increase in the mean FSH and LH levels in all the infertile males studied when compared with the fertile controls (n=35).
However, there is no significant difference in the mean levels of testosterone between the infertile and fertile men. 相似文献
65.
B. C. Harinath Satish Kumar M. V. R. Reddy 《Indian journal of clinical biochemistry : IJCB》1997,12(1):8-12
In vitro released antigens by living parasites or bacteria underin vitro maintenance or short term culture showing specific humoral immune response have been explored in development of immunodiagnostics for infectious diseases such as filariasis and tuberculosis in our laboratory. ELISA usingB. malayi mf ES antigen has been explored for detecting IgG antibody by Indirect ELISA and antigen by Inhibition ELISA and in immunomonitoring of carriers as well as clinical filarial cases. A ten year follow up of mf carriers with DEC therapy showed disapperance of antigen and antibody followed by reappearance in few cases in an endemic area. None of the cases followed developed clinical symptoms suggesting the need for long term monitoring and treatment of microfilaraemic carriers. Further immunomonitoring was found to be useful in confirming filaria aetiology in the absence of microfilaremia and determining appropriate period of treatment of acute, early clinical and occult filarial infections for clinical relief and cure.Indirect Stick Penicillinase ELISA system using Mtb EST-6 antigen for detecting tuberculous IgG antibody and a Sandwich Penicillinase ELISA system using affinity purified antibody for detecting circulating antigen were explored in tuberculosis. A combination of both the assay systems with a sensitivity of 70% and specificity of 98% was found to be promising in the precise diagnosis of pulmonary tuberculosis. Further antigen detection was found to be useful in bone and joint tuberculosis. 相似文献
66.
A. Alikhan U. M. Padigel B. V. Rama Rao B. Advani M. V. R. Reddy P. Chaturvedi B. C. Harinath 《Indian journal of clinical biochemistry : IJCB》1994,9(1):31-34
The study was conducted in filarial endemic area for various clinical presentations and diagnosis of occult filariasis. A total of 157 cases of various clinical presentations namely tropical pulmonary eosinophilia, monoarthritis, polyarthritis, glomerulonephropathy, tenosynovitis, inguinal lymphadenopathy, generalised lymphadenopathy, retroperitonial lymphadenopathy, endomyocardial fibrosis and acute conjunctivitis were screened for filarial antigen and antibody by enzyme linked immunosorbent assay (ELISA). Out of 157 cases, 107 cases were positive for antigen or antibody, suggesting the role of filarial infection in these clinical presentations. All the 107 cases were treated with diethylcarbamazine citrate (DEC) and some of the patients who were followed showed relief in signs and symptoms. Hence assay of filarial antigen and/or antibody may be useful for diagnosing occult filarial syndromes for better management and further appropriate treatment. 相似文献
67.
Swati Banerjee E Raji Nair Satish Kumar M. V. R. Reddy Bhaskar C. Harinath 《Indian journal of clinical biochemistry : IJCB》2001,16(2):203-206
Analysis of tubercular antibody, circulating free and immune complexed antigen (CIC-Ag) was done in confimed pulmonary tuberculosis
sera by ELISA, using ES-31 antigen and affinity purified anti ES-31 antibody. Twenty three of 25 (92%) tuberculosis sera were
positive for IgG antibody to ES-31 antigen. Using anti ES-31 antibody, free tubercular antigen could be detected in 20 of
25 (80%) cases whereas circulating immune complexed antigen (CIC-Ag) in 18 of 25 (72%) cases by sandwich ELISA. Of the two
sera showing absence of antibody, one showed presence of free and CIC-Ag whereas the other showed the presence of free antigen.
Thus antigen assay may be used as an adjunct tool for confirmation of pulmonary tuberculosis. 相似文献
68.
L. Hema Bindu P. Usha Rani P. P. Reddy 《Indian journal of clinical biochemistry : IJCB》2007,22(2):32-35
Calcineurin, a Ca2+—Calmodulin dependent protein phosphatase, is important for Ca2+ mediated signal transduction. The main objective of this study was to examine the potential role of calcineurin in idiopathic
mental handicap. Calcineurin levels were estimated in 20 children in the age group of 5–16 years with idiopathic mental handicap
attending the Special. Education Centre for the Mentally Handicapped in Hyderabad. The results of the present study showed
decreased activity of serum calcineurin in children with idiopathic mental handicap compared to those of normal subjects in
the same age group. The observations thus suggest impaired calcineurin activity in children with mental handicap. Calcineurin
that is involved in biosynthesis and release of neurotransmitters at the synaptic terminal brain is affected thereby causing
brain damage and leading to mental handicap. Impaired calcineurin activity was already indicated in many human diseases such
as Down's syndrome, Alzheimers, Brain ischemia, cardiac hypertrophy etc. It is therefore necessary to check the calcineurin
levels in children with mental handicap to understand the role of calcineurin in the causation of Mental handicap. 相似文献
69.
Mahajan RS Veerpathran A Dakshinamoorthy G Sharma RD Goswami K Reddy MV 《Indian journal of clinical biochemistry : IJCB》2010,25(4):362-366
WHO-Tropical Disease Research scheme highlighted the need for development of new anti-filarial drugs. Certain antibiotics
have recently been found effective against Wolbachia, co-existing symbiotically with filarial parasites. Inflammatory response
entails oxidative mechanism to educe direct anti-microbial effect. In the present study microfilariae were maintained in vitro
in medium supplemented with varying concentrations of tetracycline, doxycycline (20–100 μg/ml) or ciprofloxacin (50–250 μg/ml)
separately to find out any involvement of oxidative mechanism in the anti-filarial effect of these antibiotics. Loss of motility
of the microfilariae was measured after 48 h and correlated with the levels of MDA, nitric oxide and protein-carbonylation.
Significant loss of microfilarial motility was recorded with increasing concentration of tetracycline and doxycycline but
with ciprofloxacin the effect was not marked. Agents with high antifilarial activity revealed significant association with
oxidative parameters in a dose dependent manner. The result suggests that oxidative effect might be exploited to design novel
antifilarial drug candidate. 相似文献
70.
V. U. Reddy 《Resonance》1998,3(10):79-88
Fast Fourier transform (FFT) is an efficient algorithm for computing the discrete Fourier transform. The discovery of the
FFT algorithm paved the way for widespread use of digital methods of spectrum estimation which influenced the research in
almost every field of engineering and science. In this article, we will first introduce the continuous-time Fourier transform
(CFT), discretetime Fourier transform and discrete Fourier transform (DFT) and then present an example to illustrate the relation
between CFT and DFT. In particular, we bring out the fact that the DFT is a tool to estimate the samples of the CFT at uniformly
spaced frequencies. Next, we introduce the FFT algorithm giving certain key steps in its development. 相似文献