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51.
Research in Science Education - Despite the fact that the majority of museum visitors are often very young children, much research in museums focuses on pre-teen learners (ages 8–12). Our...  相似文献   
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High‐quality early childhood education has been shown to improve school outcomes in several developing and developed nations. The history of policy around pre‐school education in Costa Rica is described as background to presenting cross‐sectional data on the emergent literacy skills of low‐income Costa Rican children in kindergarten, 1st and 2nd grade from six schools (n?=?335). These data suggest that Costa Rican children show rather limited emergent literacy knowledge at the end of kindergarten. In addition, instruction in nine kindergarten classrooms is described and evaluated in order to provide vignettes of educational practice. The need for developmentally appropriate practice around emergent literacy skills and articulation with 1st grade is discussed and appropriate professional development is called for.  相似文献   
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Women are clearly underrepresented in institutions of science and higher education. This article focuses on an analysis of the social, economic, and political determinants of the presence of women in academe and their scientific careers, in Poland, in the 1990s portrayed in an historical perspective.  相似文献   
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The goal of this longitudinal study was to explore whether early measures of attention and inattention would be predictive of later attentiveness and whether there was any evidence of stable individual differences in attentiveness. Both full-term and preterm children were observed at 1, 2, and 3.5 years in free play and in more structured situations. For the group as a whole, and for full-terms separately, quantitative measures of inattention at 2 years were predictive of comparable measures at 3.5 years. For preterms separately, quantitative measures of inattention at 1 year were predictive of both behavior and the mothers' rating on the Conners Hyperactivity subscale at 3.5 years. Global, qualitative ratings of attentiveness at 1 and 2 years were predictive of mothers' ratings on the Conners at 3.5 years for the group as a whole and for full-terms separately. For full-terms only, the global ratings of attentiveness at 1 and 2 years were also predictive of 3.5-year quantitative measures of behavior. These data provide an encouraging base for further investigation of early individual differences in attentiveness and of possible early precursors of later attention deficits.  相似文献   
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The coincidence-anticipation timing (CAT) task assesses one facet of cognitive and motor performance and is used to understand the human visuo-motor system involved in intercepting the moving object. To assess the test–retest reliability and the concurrent validity in the Bridge Games package (Bridge) developed to assess the CAT task, the scores of 224 healthy subjects (M = 52.2, SD = 19.5 years old) were measured using the Bridge and the ‘gold standard’ Bassin Anticipation Timer (Bassin). A mean block of absolute, constant, and variable errors was calculated. Reliability and validity were expressed using intraclass correlation coefficients (ICC2,k), standard error of measurement, minimal detectable change, and Pearson’s correlation. Reliability was good to excellent for all blocks (.73 ≤ ICC ≤ .88), and the validity was good to excellent when compared using Pearson’s correlation coefficient, suggesting that the two tests may have similar properties. Bridge is an alternative to existing clinical tests for the CAT task.  相似文献   
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The effects of training on FNDC5/irisin and its association with fitness and metabolic marker improvements induced by training have been poorly investigated in humans. Thus, the present study assessed the effects of combined training (CT) on FNDC5/irisin levels, metabolic markers and fitness adaptations in obese men. Middle-age obese men (age 49.13?±?5.75, body mass index (BMI) 30.86?±?1.63) were randomly distributed in the CT group (n?=?12) and control group (CG n?=?10). The CT consisted of strength followed by aerobic training, 3 times/week, for 24 weeks. Body composition, physical fitness, plasma FNDC5/irisin, biochemical markers and metabolic scores/index were evaluated. CT maintained FNDC5/irisin levels (µg/mL) (pre: 4.15?±?0.32, post: 4.21?±?0.32; p?=?.96) and improved body composition, metabolic and physical fitness markers. In the CG, decreased FNDC5/irisin (µg/mL) (pre: 4.36?±?0.23, post: 3.57?±?0.94; p?=?.01) and reduced strength (supine exercise/kg) (pre: 71?±?14.7, post: 60.1?±?14.05; p?<?.01) were observed, along with a trend to increase HOMA-IR (pre: 2.63?±?1.11, post: 3.14?±?1.27; p?=?.07) and other indicators of metabolic deterioration. An inverse correlation was found between the change (Δ%) in levels of FNDC5/irisin and Δ% glucose, Δ% total cholesterol, Δ% triglycerides and Δ% waist circumference, in addition to a positive relation with Δ% muscle strength. In conclusion, CT maintained FNDC5/irisin levels and provided metabolic and fitness benefits. The correlation between FNDC5/irisin changes and metabolic parameters, as well as the FNDC5/irisin reduction associated with fitness and metabolic worsening in the CG, suggests a relationship between FNDC5/irisin and a healthy metabolic status in humans.  相似文献   
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In this project, we worked in partnership with school teachers who are frequent users of experimental kits available for loan to schools using the historical-investigative approach. The original kits bring a traditional approach to experimentation, without the presence of the history of science. We developed and implemented new guides to the kits, without changing their materials and instruments. Design-based research supports the development methodology; the school science topics covered in this paper are Joseph Black’s studies on latent and specific heat. Although some of the challenges faced in the implementation of historical-investigative approach are known and well-documented, the present article addresses teachers’ perspectives and some of the problems they faced in the implementation process, most of them related to school and teacher working conditions. Even though this is a case study with a small number of schools and teachers, it is possible to say that there is a huge gap to overcome before the historical-investigative approach can be implemented in large scale.

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IntroductionThe study aimed to investigate the prevalence and titres of anti-SARS-CoV-2 antibodies in children treated at the Children’s Hospital Zagreb in the first and the second wave of the COVID-19 pandemic. Statistical significance of difference at two time points was done to determine how restrictive epidemiological measures and exposure of children to COVID-19 infection affect this prevalence in different age groups.Materials and methodsAt the first time point (13th to 29th May 2020), 240 samples and in second time point (24th October to 23rd November 2020), 308 serum samples were tested for anti-SARS-CoV-2 antibodies by enzyme-linked immunosorbent assay (ELISA) and electrochemiluminescence immunoassay (ECLIA). Confirmation of results and titre determination was done using virus micro-neutralization test. Subjects were divided according to gender, age and epidemiological history.ResultsSeroprevalence of anti-SARS-CoV-2 antibodies differs significantly in two time points (P = 0.010). In first time point 2.9% of seropositive children were determined and in second time point 8.4%. Statistically significant difference (P = 0.007) of seroprevalence between two time points was found only in a group of children aged 11-19 years. At the first time point, all seropositive children were asymptomatic with titre < 8. At the second time point, 69.2% seropositive children were asymptomatic with titre ≥ 8.ConclusionsThe prevalence of anti-SARS-CoV-2 antibodies was significantly lower at the first time point than at the second time point. Values of virus micro-neutralization test showed that low titre in asymptomatic children was not protective at the first time point but in second time point all seropositive children had protective titre of anti-SARS-CoV-2 antibodies.  相似文献   
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