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41.
The present study was undertaken to determine the significance of sex hormone binding globulin, the major and specific binding protein for testosterone and estradiol, in breast cancer. Among breast cancer patients, lower serum levels of Sex hormone binding globulin and higher levels of testosterone were observed. Sex hormone binding globulin showed an inverse relationship with testosterone and total cholesterol, and a direct relation with HDL-cholesterol. By the western blot analyses, Sex hormone binding globulin was detected in all biological samples that we examined. In the breast tumor tissue sections, immuno-staining for Sex hormone binding globulin was confined in cell cytoplasm and 29% cases were positive, which showed no association with the investigated prognostic markers of breast cancer such as ER and HER-2/neu over-expression. In this study, decreased circulating levels of Sex hormone binding globulin in breast cancer patients possibly indicate higher bioavailable estrogens.  相似文献   
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Editorial     
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Studies of pedagogical relationships offer insights into policies and practices which have the capacity to promote progressive change in educational practice for children in poverty. This paper focuses on relationships established in three differently‐located Australian primary schools: Greytown, a medium sized inner‐city school in New South Wales; Mungar, a large suburban school in Queensland; and Meiki, a small rural school in New South Wales. Each school is a designated disadvantaged school and funded accordingly through a federal Disadvantaged Schools Program, is located in a working class area, and is ethnically diverse. The schools’ pedagogical responses to children in poverty are contrasted and analysed in terms of their capacity to contribute to socially just outcomes from schooling.  相似文献   
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Significant adults who support and teach children are only too aware of the effects of adverse experiences on intellectual, social and personal development. Less easily predicted, however, is a small number of young people who, despite many negative experiences, seem to make a considerable success of their lives. In this paper, the intriguing notion of 'resilience' will be explored and some suggestions will be offered on how educational psychologists could use both the concept and the underpinning research to challenge current practice in childcare and education, and to generate strategies for carers and teachers that can enable them to enhance the resilience of vulnerable children and young people.  相似文献   
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This article discusses project work in university mathematics education. The practice perspective is obtained as students and teachers from Aalborg University share their experiences. A theoretical framework is introduced. It includes the following key-terms: Problem-centered studies, interdisciplinarity, participant-directed studies, and the exemplarity principle. The contrasting of this theoretical conception of project work with the practice shows that the original notion of project work has been modified as a consequence of its encounter with practice. The modification can be perceived as both a success and a failure. To discuss this, different perspectives on project work in mathematics are suggested.  相似文献   
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While many universities have taken steps to recognise teaching in academic promotions, debate continues on the teaching criteria to be used and their evaluation. This article analyses the 10 criteria that inform the evaluation of teaching and eventual promotion decisions at a South African university: rationale for teaching, teaching methods, postgraduate supervision, assessment, student evaluations, peer evaluations, ongoing study of higher education, developing courses, sharing teaching experiences and special recognition of teaching. The study investigated which criteria, if any, were significant in the overall evaluation of teaching and in academic promotion outcomes for different rank levels. The unexpected key finding was that each of the criteria demonstrated statistically significant correlations and differences with both teaching evaluations and promotion outcomes. While all 10 teaching criteria mattered in the evaluation of teaching and academic promotion outcomes, postgraduate supervision and sharing teaching experiences were especially important for those who were successful at the rank of full professor. A multidimensional approach that rigorously assesses multiple criteria in evaluating teaching at all rank levels, including the professoriate, contributes to its credence and currency in academic promotions. Analyses of actual assessments of teaching criteria and their relation to promotion outcomes can contribute to consensus on evaluating teaching.  相似文献   
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Abstract

This study proposes and verifies the concept of a technology disposition in teacher education, which is comprised of predisposition and competence. It examines the reliability and validity of a measure of the technology disposition of teacher education students, the Technology Disposition Scale for Teacher Education Students (TDS‐T). The TDS‐T is comprised of two subscales: technology predisposition and technology competence. In this study, the TDS‐T was completed by 656 teacher education students. Results showed the proposed disposition model of predisposition and competence had significant relationships with gender and class year. Male students had significantly higher overall technology disposition scores than did female students, but these differences were due to the male students' strong self‐concept, especially self‐confidence. Students technology competence level was significantly higher for seniors than for sophomores, and the overall technology disposition scores significantly increased from students' junior to senior years. The TDS‐T demonstrated content validity through factor analysis and convergent and discriminate validity through item analysis. The value for Cronbach's alpha was .93, indicating highly satisfactory reliability.  相似文献   
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